메뉴 건너뛰기




Volumn 18, Issue 7, 2007, Pages 773-779

Estrogen-dependent regulation of Eg5 in breast cancer cells

Author keywords

Breast cancer; Cell cycle; Eg5; Estrogen receptor; Kinesin

Indexed keywords

ANTIESTROGEN; DEFEROXAMINE; EG5 PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; KINESIN; MONASTROL; PACLITAXEL; PHORBOL 13 ACETATE 12 MYRISTATE; RIBONUCLEASE; TAMOXIFEN; TRITYL DERIVATIVE; TRITYLCYSTEINE; UNCLASSIFIED DRUG;

EID: 34250889281     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e3280a02f2b     Document Type: Article
Times cited : (6)

References (26)
  • 1
    • 0029417238 scopus 로고
    • cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 1995; 83:1159-1169.
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1    Lane, H.A.2    d'Hérin, P.3    Harper, M.4    Kress, M.5    Nigg, E.A.6
  • 2
  • 4
    • 22244459880 scopus 로고    scopus 로고
    • Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
    • Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, et al. Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 2005; 8:49-59.
    • (2005) Cancer Cell , vol.8 , pp. 49-59
    • Tao, W.1    South, V.J.2    Zhang, Y.3    Davide, J.P.4    Farrell, L.5    Kohl, N.E.6
  • 5
    • 15744404844 scopus 로고    scopus 로고
    • Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and sensitive cancer cells
    • Marcus AI, Peters U, Thomas SL, Garrett S, Zelnak A, Kapoor TM, et al. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and sensitive cancer cells. J Biol Chem 2005; 280:11569-11577.
    • (2005) J Biol Chem , vol.280 , pp. 11569-11577
    • Marcus, A.I.1    Peters, U.2    Thomas, S.L.3    Garrett, S.4    Zelnak, A.5    Kapoor, T.M.6
  • 6
    • 33745867225 scopus 로고    scopus 로고
    • Skoufias DA, DeBonis S, Saoudi Y, Lebeau L, Crevel I, Wade RH, et al. S-trityl-L-cysteine is a reversible, tight-binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem 2006; 281:17559-17569.
    • Skoufias DA, DeBonis S, Saoudi Y, Lebeau L, Crevel I, Wade RH, et al. S-trityl-L-cysteine is a reversible, tight-binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem 2006; 281:17559-17569.
  • 8
    • 33645023929 scopus 로고    scopus 로고
    • Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line
    • Davis DA, Sarkar SH, Hussain M, Li Y, Sarkar FH. Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line. BMC Cancer 2006; 6:22.
    • (2006) BMC Cancer , vol.6 , pp. 22
    • Davis, D.A.1    Sarkar, S.H.2    Hussain, M.3    Li, Y.4    Sarkar, F.H.5
  • 9
    • 33745810892 scopus 로고    scopus 로고
    • Inhibition of the mitotic kinesin Eg5 up-regulates HSP70 through the phophatidylinositol-3- kinase/Akt pathway in multiple myeloma cells
    • Liu M, Aneja R, Liu C, Sun L, Gao J, Wang H, et al. Inhibition of the mitotic kinesin Eg5 up-regulates HSP70 through the phophatidylinositol-3- kinase/Akt pathway in multiple myeloma cells. J Biol Chem 2006; 281:18090-18097.
    • (2006) J Biol Chem , vol.281 , pp. 18090-18097
    • Liu, M.1    Aneja, R.2    Liu, C.3    Sun, L.4    Gao, J.5    Wang, H.6
  • 10
    • 33748295692 scopus 로고    scopus 로고
    • Fulvestrant: Pharmacologic profile versus existing endocrine agents for the treatment of breast cancer
    • Buzdar AU, Robertson JFR. Fulvestrant: pharmacologic profile versus existing endocrine agents for the treatment of breast cancer. Ann Pharmacother 2006; 40:1572-1583.
    • (2006) Ann Pharmacother , vol.40 , pp. 1572-1583
    • Buzdar, A.U.1    Robertson, J.F.R.2
  • 11
    • 1842684035 scopus 로고    scopus 로고
    • Fulvestrant: An oestrogen receptor antagonist with a novel mechanism of action
    • Osborne CK, Wakeling A, Nicholson RI. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer 2004; 90 (Suppl):S2-S6.
    • (2004) Br J Cancer , vol.90 , Issue.SUPPL.
    • Osborne, C.K.1    Wakeling, A.2    Nicholson, R.I.3
  • 13
    • 0030927929 scopus 로고    scopus 로고
    • Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution
    • Planas-Silva MD, Weinberg RA. Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution. Mol Cell Biol 1997; 17:4059-4069.
    • (1997) Mol Cell Biol , vol.17 , pp. 4059-4069
    • Planas-Silva, M.D.1    Weinberg, R.A.2
  • 14
    • 31044447246 scopus 로고    scopus 로고
    • Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer
    • Planas-Silva MD, Bruggeman RD, Grenko RT, Smith JS. Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. Biochem Biophys Res Commun 2006; 341:73-81.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 73-81
    • Planas-Silva, M.D.1    Bruggeman, R.D.2    Grenko, R.T.3    Smith, J.S.4
  • 15
    • 0033516659 scopus 로고    scopus 로고
    • Kaiser A, Brembeck FH, Nicke B, Wiedenmann B, Riecken E-O, Rosewicz S. All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5. J Biol Chem 1999; 274:18925-18931.
    • Kaiser A, Brembeck FH, Nicke B, Wiedenmann B, Riecken E-O, Rosewicz S. All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5. J Biol Chem 1999; 274:18925-18931.
  • 16
    • 25844515780 scopus 로고    scopus 로고
    • Downstream targets of growth factor and oestrogen signalling and endocrine resistance: The potential roles of c-Myc, cyclin D1 and cyclin E
    • Butt AJ, McNeil CM, Musgrove EA, Sutherland RL. Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E. Endocr Relat Cancer 2005; 12:S47-S59.
    • (2005) Endocr Relat Cancer , vol.12
    • Butt, A.J.1    McNeil, C.M.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 17
    • 0034623995 scopus 로고    scopus 로고
    • A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence
    • Carroll JS, Prall OWJ, Musgrove EA, Sutherland RL. A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence. J Biol Chem 2000; 275:38221-38229.
    • (2000) J Biol Chem , vol.275 , pp. 38221-38229
    • Carroll, J.S.1    Prall, O.W.J.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 18
    • 0034605123 scopus 로고    scopus 로고
    • Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5
    • Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J Cell Biol 2000; 150:975-988.
    • (2000) J Cell Biol , vol.150 , pp. 975-988
    • Kapoor, T.M.1    Mayer, T.U.2    Coughlin, M.L.3    Mitchison, T.J.4
  • 20
    • 0035171325 scopus 로고    scopus 로고
    • Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells
    • Pahl PMB, Horwitz MA, Horwitz KB, Horwitz LD. Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells. Breast Cancer Res Treat 2001; 69:69-79.
    • (2001) Breast Cancer Res Treat , vol.69 , pp. 69-79
    • Pahl, P.M.B.1    Horwitz, M.A.2    Horwitz, K.B.3    Horwitz, L.D.4
  • 21
    • 0023122820 scopus 로고
    • Influence of 12-O-tetradecnoylphorbol-13-acetate on proliferation and maturation of human breast carcinoma cells (MCF-7): Relationship to cell cycle events
    • Valette A, Gas N, Jozan S, Roubinet F, Dupont MA, Bayard F. Influence of 12-O-tetradecnoylphorbol-13-acetate on proliferation and maturation of human breast carcinoma cells (MCF-7): relationship to cell cycle events. Cancer Res 1987; 47:1615-1620.
    • (1987) Cancer Res , vol.47 , pp. 1615-1620
    • Valette, A.1    Gas, N.2    Jozan, S.3    Roubinet, F.4    Dupont, M.A.5    Bayard, F.6
  • 23
    • 0025866163 scopus 로고
    • Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells
    • Doucas V, Spyrou G, Yaniv M. Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells. EMBO J 1991; 10:2237-2245.
    • (1991) EMBO J , vol.10 , pp. 2237-2245
    • Doucas, V.1    Spyrou, G.2    Yaniv, M.3
  • 24
    • 0024381743 scopus 로고
    • Modulation of estrogen receptor and epidermal growth factor receptor mRNAs by phorbol ester in MCF 7 breast cancer cells
    • Lee CSL, Koga M, Sutherland RL. Modulation of estrogen receptor and epidermal growth factor receptor mRNAs by phorbol ester in MCF 7 breast cancer cells. Bioch Biophys Res Commun 1989; 162:415-421.
    • (1989) Bioch Biophys Res Commun , vol.162 , pp. 415-421
    • Lee, C.S.L.1    Koga, M.2    Sutherland, R.L.3
  • 25
    • 0028810248 scopus 로고
    • Effects of 12-O-tetradecanoylphorbol-13-acetate on estrogen receptor activity in MCF-7 cells
    • Martin MB, Garcia-Morales P, Stoica A, Solomon HB, Pierce M, Katz D, et al. Effects of 12-O-tetradecanoylphorbol-13-acetate on estrogen receptor activity in MCF-7 cells. J Biol Chem 1995; 270:25244- 25251.
    • (1995) J Biol Chem , vol.270 , pp. 25244-25251
    • Martin, M.B.1    Garcia-Morales, P.2    Stoica, A.3    Solomon, H.B.4    Pierce, M.5    Katz, D.6
  • 26
    • 33644517511 scopus 로고    scopus 로고
    • Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development
    • Koller E, Propp S, Zhang H, Zhao C, Xiao X, Chang M, et al. Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development. Cancer Res 2006; 66:2059-2066.
    • (2006) Cancer Res , vol.66 , pp. 2059-2066
    • Koller, E.1    Propp, S.2    Zhang, H.3    Zhao, C.4    Xiao, X.5    Chang, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.