-
2
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V., and Greenamyre J.T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3 (2000) 1301-1306
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
3
-
-
0034007822
-
Pathoanatomy of Parkinson's disease
-
Braak H., and Braak E. Pathoanatomy of Parkinson's disease. J Neurol 247 Suppl 2 (2000) II3-II10
-
(2000)
J Neurol
, vol.247
, Issue.SUPPL. 2
-
-
Braak, H.1
Braak, E.2
-
4
-
-
0037227378
-
Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices
-
Bywood P.T., and Johnson S.M. Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices. Exp Neurol 179 (2003) 47-59
-
(2003)
Exp Neurol
, vol.179
, pp. 47-59
-
-
Bywood, P.T.1
Johnson, S.M.2
-
5
-
-
0025945089
-
Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain
-
Chan P., DeLanney L.E., Irwin I., Langston J.W., and Di Monte D. Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. J Neurochem 57 (1991) 348-351
-
(1991)
J Neurochem
, vol.57
, pp. 348-351
-
-
Chan, P.1
DeLanney, L.E.2
Irwin, I.3
Langston, J.W.4
Di Monte, D.5
-
6
-
-
0033389550
-
Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide
-
Cosi C., and Marien M. Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide. Ann N Y Acad Sci 890 (1999) 227-239
-
(1999)
Ann N Y Acad Sci
, vol.890
, pp. 227-239
-
-
Cosi, C.1
Marien, M.2
-
7
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W., and Przedborski S. Parkinson's disease: mechanisms and models. Neuron 39 (2003) 889-909
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
8
-
-
3542993306
-
Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration
-
Drolet R.E., Behrouz B., Lookingland K.J., and Goudreau J.L. Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration. Neurotoxicology 25 (2004) 761-769
-
(2004)
Neurotoxicology
, vol.25
, pp. 761-769
-
-
Drolet, R.E.1
Behrouz, B.2
Lookingland, K.J.3
Goudreau, J.L.4
-
9
-
-
0025954066
-
-
Fearnley JM, Lees AJ Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114 (Pt 5):2283-2301.
-
-
-
-
11
-
-
0024434128
-
Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization
-
German D.C., Manaye K., Smith W.K., Woodward D.J., and Saper C.B. Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Ann Neurol 26 (1989) 507-514
-
(1989)
Ann Neurol
, vol.26
, pp. 507-514
-
-
German, D.C.1
Manaye, K.2
Smith, W.K.3
Woodward, D.J.4
Saper, C.B.5
-
12
-
-
0026712160
-
Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells
-
German D.C., Manaye K.F., Sonsalla P.K., and Brooks B.A. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Ann N Y Acad Sci 648 (1992) 42-62
-
(1992)
Ann N Y Acad Sci
, vol.648
, pp. 42-62
-
-
German, D.C.1
Manaye, K.F.2
Sonsalla, P.K.3
Brooks, B.A.4
-
13
-
-
11844262742
-
Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism
-
Greene J.G., Dingledine R., and Greenamyre J.T. Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiol Dis 18 (2005) 19-31
-
(2005)
Neurobiol Dis
, vol.18
, pp. 19-31
-
-
Greene, J.G.1
Dingledine, R.2
Greenamyre, J.T.3
-
14
-
-
84985280160
-
The efficiency of systematic sampling in stereology and its prediction
-
Gundersen H.J., and Jensen E.B. The efficiency of systematic sampling in stereology and its prediction. J Microsc 147 Pt 3 (1987) 229-263
-
(1987)
J Microsc
, vol.147
, Issue.PART 3
, pp. 229-263
-
-
Gundersen, H.J.1
Jensen, E.B.2
-
15
-
-
0026637866
-
Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease?
-
Hirsch E.C. Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease?. Ann Neurol 32 Suppl (1992) S88-S93
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL
-
-
Hirsch, E.C.1
-
16
-
-
0030614644
-
Neuronal vulnerability in Parkinson's disease
-
Hirsch E.C., Faucheux B., Damier P., Mouatt-Prigent A., and Agid Y. Neuronal vulnerability in Parkinson's disease. J Neural Transm Suppl 50 (1997) 79-88
-
(1997)
J Neural Transm Suppl
, vol.50
, pp. 79-88
-
-
Hirsch, E.C.1
Faucheux, B.2
Damier, P.3
Mouatt-Prigent, A.4
Agid, Y.5
-
17
-
-
0029090834
-
1-Methyl-4-phenyl-pyridinium (MPP+) uptake does not explain the differential toxicity of MPP+ in the nigrostriatal and mesolimbic dopaminergic pathways
-
Hung H.C., Tao P.L., and Lee E.H. 1-Methyl-4-phenyl-pyridinium (MPP+) uptake does not explain the differential toxicity of MPP+ in the nigrostriatal and mesolimbic dopaminergic pathways. Neurosci Lett 196 (1995) 93-96
-
(1995)
Neurosci Lett
, vol.196
, pp. 93-96
-
-
Hung, H.C.1
Tao, P.L.2
Lee, E.H.3
-
18
-
-
0017928838
-
The hypothalamus in Parkinson disease
-
Langston J.W., and Forno L.S. The hypothalamus in Parkinson disease. Ann Neurol 3 (1978) 129-133
-
(1978)
Ann Neurol
, vol.3
, pp. 129-133
-
-
Langston, J.W.1
Forno, L.S.2
-
19
-
-
0025213396
-
Effects of probenecid on striatal dopamine depletion in acute and long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice
-
Lau Y.S., Trobough K.L., Crampton J.M., and Wilson J.A. Effects of probenecid on striatal dopamine depletion in acute and long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Gen Pharmacol 21 (1990) 181-187
-
(1990)
Gen Pharmacol
, vol.21
, pp. 181-187
-
-
Lau, Y.S.1
Trobough, K.L.2
Crampton, J.M.3
Wilson, J.A.4
-
20
-
-
0032826958
-
Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice
-
Le W., Conneely O.M., Zou L., He Y., Saucedo-Cardenas O., Jankovic J., Mosier D.R., and Appel S.H. Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Exp Neurol 159 (1999) 451-458
-
(1999)
Exp Neurol
, vol.159
, pp. 451-458
-
-
Le, W.1
Conneely, O.M.2
Zou, L.3
He, Y.4
Saucedo-Cardenas, O.5
Jankovic, J.6
Mosier, D.R.7
Appel, S.H.8
-
21
-
-
0025021782
-
3,4-Dihydroxyphenylacetic acid concentrations in the intermediate lobe and neural lobe of the posterior pituitary gland as an index of tuberohypophysial dopaminergic neuronal activity
-
Lindley S.E., Gunnet J.W., Lookingland K.J., and Moore K.E. 3,4-Dihydroxyphenylacetic acid concentrations in the intermediate lobe and neural lobe of the posterior pituitary gland as an index of tuberohypophysial dopaminergic neuronal activity. Brain Res 506 (1990) 133-138
-
(1990)
Brain Res
, vol.506
, pp. 133-138
-
-
Lindley, S.E.1
Gunnet, J.W.2
Lookingland, K.J.3
Moore, K.E.4
-
22
-
-
0026713852
-
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
-
Liu Y., Peter D., Roghani A., Schuldiner S., Prive G.G., Eisenberg D., Brecha N., and Edwards R.H. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell 70 (1992) 539-551
-
(1992)
Cell
, vol.70
, pp. 539-551
-
-
Liu, Y.1
Peter, D.2
Roghani, A.3
Schuldiner, S.4
Prive, G.G.5
Eisenberg, D.6
Brecha, N.7
Edwards, R.H.8
-
23
-
-
33751254332
-
Functional neuroanatomy of hypothalamic dopaminergic neuroendocrine systems
-
Dunnett S.B., et al. (Ed), Elsevier, Amsterdam
-
Lookingland K.J., and Moore K.E. Functional neuroanatomy of hypothalamic dopaminergic neuroendocrine systems. In: Dunnett S.B., et al. (Ed). Handbook of chemical neuroanatomy Vol. 21 (2005), Elsevier, Amsterdam 433-521
-
(2005)
Handbook of chemical neuroanatomy
, vol.21
, pp. 433-521
-
-
Lookingland, K.J.1
Moore, K.E.2
-
24
-
-
0034624017
-
The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity
-
Lotharius J., and O'Malley K.L. The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity. J Biol Chem 275 (2000) 38581-38588
-
(2000)
J Biol Chem
, vol.275
, pp. 38581-38588
-
-
Lotharius, J.1
O'Malley, K.L.2
-
26
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders
-
Masliah E., Rockenstein E., Veinbergs I., Mallory M., Hashimoto M., Takeda A., Sagara Y., Sisk A., and Mucke L. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 287 (2000) 1265-1269
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
27
-
-
0022197486
-
Mesolimbic dopaminergic neurons are not spared by MPTP neurotoxicity in mice
-
Melamed E., Rosenthal J., Globus M., Cohen O., Frucht Y., and Uzzan A. Mesolimbic dopaminergic neurons are not spared by MPTP neurotoxicity in mice. Eur J Pharmacol 114 (1985) 97-100
-
(1985)
Eur J Pharmacol
, vol.114
, pp. 97-100
-
-
Melamed, E.1
Rosenthal, J.2
Globus, M.3
Cohen, O.4
Frucht, Y.5
Uzzan, A.6
-
28
-
-
0023935132
-
Effects of systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to mice on tyrosine hydroxylase, L-3,4-dihydroxyphenylalanine decarboxylase, dopamine beta-hydroxylase, and monoamine oxidase activities in the striatum and hypothalamus
-
Mogi M., Harada M., Kojima K., Kiuchi K., and Nagatsu T. Effects of systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to mice on tyrosine hydroxylase, L-3,4-dihydroxyphenylalanine decarboxylase, dopamine beta-hydroxylase, and monoamine oxidase activities in the striatum and hypothalamus. J Neurochem 50 (1988) 1053-1056
-
(1988)
J Neurochem
, vol.50
, pp. 1053-1056
-
-
Mogi, M.1
Harada, M.2
Kojima, K.3
Kiuchi, K.4
Nagatsu, T.5
-
29
-
-
0015697938
-
Isolated removal of hypothalamic or other brain nuclei of the rat
-
Palkovits M. Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res 59 (1973) 449-450
-
(1973)
Brain Res
, vol.59
, pp. 449-450
-
-
Palkovits, M.1
-
30
-
-
0035960066
-
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment
-
Petroske E., Meredith G.E., Callen S., Totterdell S., and Lau Y.S. Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience 106 (2001) 589-601
-
(2001)
Neuroscience
, vol.106
, pp. 589-601
-
-
Petroske, E.1
Meredith, G.E.2
Callen, S.3
Totterdell, S.4
Lau, Y.S.5
-
31
-
-
0023442357
-
Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells
-
Reinhard Jr. J.F., Diliberto Jr. E.J., Viveros O.H., and Daniels A.J. Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells. Proc Natl Acad Sci U S A 84 (1987) 8160-8164
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 8160-8164
-
-
Reinhard Jr., J.F.1
Diliberto Jr., E.J.2
Viveros, O.H.3
Daniels, A.J.4
-
32
-
-
0033840581
-
MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
-
Saporito M.S., Thomas B.A., and Scott R.W. MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. J Neurochem 75 (2000) 1200-1208
-
(2000)
J Neurochem
, vol.75
, pp. 1200-1208
-
-
Saporito, M.S.1
Thomas, B.A.2
Scott, R.W.3
-
33
-
-
0030846282
-
Towards more readily comprehensible procedures in disector stereology
-
Schmitz C. Towards more readily comprehensible procedures in disector stereology. J Neurocytol 26 (1997) 707-710
-
(1997)
J Neurocytol
, vol.26
, pp. 707-710
-
-
Schmitz, C.1
-
34
-
-
0033789892
-
Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
-
Schmitz C., and Hof P.R. Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J Chem Neuroanat 20 (2000) 93-114
-
(2000)
J Chem Neuroanat
, vol.20
, pp. 93-114
-
-
Schmitz, C.1
Hof, P.R.2
-
35
-
-
11844300345
-
Design-based stereology in neuroscience
-
Schmitz C., and Hof P.R. Design-based stereology in neuroscience. Neuroscience 130 (2005) 813-831
-
(2005)
Neuroscience
, vol.130
, pp. 813-831
-
-
Schmitz, C.1
Hof, P.R.2
-
36
-
-
0036268069
-
Method for culturing postnatal substantia nigra as an in vitro model of experimental Parkinson's disease
-
Smeyne M., and Smeyne R.J. Method for culturing postnatal substantia nigra as an in vitro model of experimental Parkinson's disease. Brain Res Brain Res Protoc 9 (2002) 105-111
-
(2002)
Brain Res Brain Res Protoc
, vol.9
, pp. 105-111
-
-
Smeyne, M.1
Smeyne, R.J.2
-
37
-
-
0025118725
-
Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease
-
Sundstrom E., Fredriksson A., and Archer T. Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease. Brain Res 528 (1990) 181-188
-
(1990)
Brain Res
, vol.528
, pp. 181-188
-
-
Sundstrom, E.1
Fredriksson, A.2
Archer, T.3
-
38
-
-
0023148043
-
Studies on the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in C57BL/6 mice. Comparison with three other strains of mice
-
Sundstrom E., Stromberg I., Tsutsumi T., Olson L., and Jonsson G. Studies on the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in C57BL/6 mice. Comparison with three other strains of mice. Brain Res 405 (1987) 26-38
-
(1987)
Brain Res
, vol.405
, pp. 26-38
-
-
Sundstrom, E.1
Stromberg, I.2
Tsutsumi, T.3
Olson, L.4
Jonsson, G.5
-
39
-
-
0023133778
-
Inhibition of type A monoamine oxidase by 1-methyl-4-phenylpyridine
-
Takamidoh H., Naoi M., and Nagatsu T. Inhibition of type A monoamine oxidase by 1-methyl-4-phenylpyridine. Neurosci Lett 73 (1987) 293-297
-
(1987)
Neurosci Lett
, vol.73
, pp. 293-297
-
-
Takamidoh, H.1
Naoi, M.2
Nagatsu, T.3
-
40
-
-
0038641723
-
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
-
Teismann P., Tieu K., Choi D.K., Wu D.C., Naini A., Hunot S., Vila M., Jackson-Lewis V., and Przedborski S. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc Natl Acad Sci U S A 100 (2003) 5473-5478
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5473-5478
-
-
Teismann, P.1
Tieu, K.2
Choi, D.K.3
Wu, D.C.4
Naini, A.5
Hunot, S.6
Vila, M.7
Jackson-Lewis, V.8
Przedborski, S.9
-
41
-
-
0031979752
-
Hypothesis: the role of dopaminergic transporters in selective vulnerability of cells in Parkinson's disease
-
Uhl G.R. Hypothesis: the role of dopaminergic transporters in selective vulnerability of cells in Parkinson's disease. Ann Neurol 43 (1998) 555-560
-
(1998)
Ann Neurol
, vol.43
, pp. 555-560
-
-
Uhl, G.R.1
-
42
-
-
0026339976
-
Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
-
West M.J., Slomianka L., and Gundersen H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231 (1991) 482-497
-
(1991)
Anat Rec
, vol.231
, pp. 482-497
-
-
West, M.J.1
Slomianka, L.2
Gundersen, H.J.3
-
43
-
-
0023131195
-
Histochemical, biochemical and behavioural consequences of MPTP treatment in C-57 black mice
-
Willis G.L., and Donnan G.A. Histochemical, biochemical and behavioural consequences of MPTP treatment in C-57 black mice. Brain Res 402 (1987) 269-274
-
(1987)
Brain Res
, vol.402
, pp. 269-274
-
-
Willis, G.L.1
Donnan, G.A.2
-
44
-
-
0027304263
-
Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Zang L.Y., and Misra H.P. Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Biol Chem 268 (1993) 16504-16512
-
(1993)
J Biol Chem
, vol.268
, pp. 16504-16512
-
-
Zang, L.Y.1
Misra, H.P.2
|