Cost savings by reagent reduction in flow cytometry-based CD4+ T cell counts: An approach to improve accessibility for HIV management

Asian Pacific Journal of Allergy and Immunology

Volumn 25, Issue 1, 2007, Pages 83-89

  Buranapraditkun, Supranee ^a   Nookhai, Somboon ^b   Ubolyam, Sasiwimol ^b   Sirivichayakul, Sunee ^a   Phanuphak, Praphan ^a,b   Ruxrungtham, Kiat ^a,b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b THAI RED CROSS AIDS RESEARCH CENTRE   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD48 ANTIGEN; MONOCLONAL ANTIBODY; REAGENT;

ANTIBODY DETECTION; ARTICLE; BLOOD SAMPLING; CD4 CD8 RATIO; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CORRELATION COEFFICIENT; COST CONTROL; DIAGNOSTIC ACCURACY; FLOW CYTOMETRY; HEALTH CARE ACCESS; HEALTH CARE AVAILABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; PATIENT MONITORING; RELIABILITY; SENSITIVITY AND SPECIFICITY; THAILAND;

CD4 LYMPHOCYTE COUNT; COST SAVINGS; FLOW CYTOMETRY; HIV INFECTIONS; HUMANS; SENSITIVITY AND SPECIFICITY; THAILAND;

EID: 34250864525     PISSN: 0125877X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Zinkernagel RM. Immunosuppression by a noncytolytic virus via T cell mediated immunopathology. Implication for AIDS. Adv Exp Med Biol 1995; 374: 165-71.
2. Pinching AJ. Factors affecting the natural history of human immunodeficiency virus infection. Immunodefic Rev 1988; 1: 23-38.
3. Leonard R, Zagury D, Desportes I, Bernard J, Zagury JF, Gallo RC. Cytopathic effect of human immunodeficiency virus in T4 cells is linked to the last stage of virus infection. Proc Natl Acad Sci USA 1988; 85: 3570-4.
4. Harris JR, Kitchen AD, Harrison JF, Tovey G. Viral release from HIV-I-induced syncytia of CD4+ C8166 cells. J Med Virol 1989; 28: 81-9.
5. 3: a cost-effectiveness analysis. J Acquir Immune Defic Syndr 1991; 4: 521-31.
6. 6/l. AIDS 2001; 15: 1509-15.
7. Jordan WC. Absolute CD4 count as a predictor for Mycobacterium avium infection in AIDS patients. J Natl Med Assoc 1991; 83: 943.
8. Falco SN, Soler JB. Prevention and treatment of opportunistic infections. Allergol Immunopathol (Madr) 1998; 26: 144-50.
9. Cohn SE, Kammann E, Williams P, Currier JS, Chesney MA. Association of adherence to Mycobacterium avium complex prophylaxis and antiretroviral therapy with clinical outcomes in Acquired Immunodeficiency Syndrome. Clin Infect Dis 2002; 34: 1129-36.
10. Back DJ, Khoo SH, Gibbons SE, Barry MG, Merry C. Therapeutic drug monitoring of antiretrovirals in human immunodeficiency virus infection. Ther Drug Monit 2000; 22: 122-6.
11. Glencross DK, Scott LE. CD4 cell monitoring for HIV/AIDS: old options; new insights. SADJ 2001; 56: 602-5.
12. Coulaud JP. Quality of life and HIV seropositivity: a dynamic reflection on "the beach". Rev Infirm 1995; 37-40.
13. Lyall EG, Blott M, Ruiter A, et al. Guidelines for the management of HIV infection in pregnant women and the prevention of mother-to-child transmission. HIV Med 2001; 2: 314-34.
14. Whitley RJ, Jacobson MA, Friedberg DN, et al. Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. Arch Intern Med 1998; 158: 957-69.
15. Guidelines for using antiretroviral agents among HIV-infected adults and adolescents. Recommendations of the Panel on Clinical Practices for Treatment of HIV. MMWR Morb Mortal Wkly Rep 2002; 51: 1-55.
16. Ekpini RA, Nkengasong JN, Sibailly T, et al. Changes in plasma HIV-1-RNA viral load and CD4 cell counts, and lack of zidovudine resistance among pregnant women receiving short-course zidovudine. AIDS 2002; 16: 625-30.
17. Sterling TR, Chaisson RE, Moore RD. HIV-1 RNA, CD4 T-lymphocytes, and clinical response to highly active antiretroviral therapy. AIDS 2001; 15: 2251-7.
18. Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: a meta-analysis. HIV Surrogate Marker Collaborative Group. AIDS Res Hum Retroviruses 2000; 16: 1123-33.
19. Bene MC, Kolopp Sarda MN, El Kaissouni J, et al. Automated cell count in flow cytometry: a valuable tool to assess CD4 absolute levels in peripheral blood. Am J Clin Pathol 1998; 110: 321-6.
20. Revised guidelines for the performance of CD4+ T-cell determinations in persons with human immunodeficiency virus (HIV) infections. Centers for Disease Control and Prevention. MMWR Recomm Rep 1991; 43: 1-21.
21. Moss MW, Carella AV, Provost V, Quinn TC. Comparison of absolute CD4+ lymphocyte counts determined by enzyme immunoassay (TRAx CD4 test kit) and flow cytometry. Clin Diagn Lab Immunol 1996; 3: 371-3.
22. Lyamuya EF, Kagoma C, Mbena EC, et al. Evaluation of the FACScount, TRAx CD4 and Dynabeads methods for CD4 lymphocyte determination. J Immunol Methods 1996; 195: 103-12.
23. Johnson D, Hirschkom D, Busch MP. Evaluation of four alternative methodologies for determination of absolute CD4+ lymphocyte counts. The National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 10: 522-30.
24. Pattanapanyasat K, Lerdwana S, Shain H, et al. Low-cost CD4 enumeration in HIV-infected patients in Thailand. Asian Pac J Allergy Immunol 2003; 21: 105-13.