Adrenergic receptor genotype but not perioperative bisoprolol therapy may determine cardiovascular outcome in at-risk patients undergoing surgery with spinal block: The Swiss Beta Blocker in Spinal Anesthesia (BBSA) study: A double-blinded, placebo-controlled, multicenter trial with 1-year follow-up

Anesthesiology

Volumn 107, Issue 1, 2007, Pages 33-44

  Zaugg, Michael ^a,g   Bestmann, Lukas ^b   Wacker, Johannes ^a   Lucchinetti, Eliana ^a   Boltres, Anita ^a   Schulz, Christian ^a   Hersberger, Martin ^b   Kälin, Gabriela ^b   Furrer, Lukas ^d   Hofer, Christoph ^d   Blumenthal, Stephan ^e   Müller, Annabelle ^c   Zollinger, Andreas ^d   Spahn, Donat R ^f   Borgeat, Alain ^e  

^a Institute of Anesthesiology   (Switzerland)

^b Institute of Clinical Chemistry

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d TRIEMLI HOSPITAL   (Switzerland)

^e ORTHOPEDIC UNIVERSITY HOSPITAL BALGRIST   (Switzerland)

^f LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^g UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR; ARGININE; BISOPROLOL; GLYCINE; PLACEBO;

ADULT; AGED; ARTICLE; BRADYCARDIA; BRONCHOSPASM; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIRIUM; DOUBLE BLIND PROCEDURE; DRUG SAFETY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART DEATH; HEART INFARCTION; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; PSYCHOSIS; RANDOMIZED CONTROLLED TRIAL; SPINAL ANESTHESIA; STROKE; TREATMENT DURATION; TREATMENT OUTCOME;

ADRENERGIC BETA-ANTAGONISTS; ANESTHESIA, SPINAL; BISOPROLOL; CARDIOMYOPATHY, DILATED; CARDIOVASCULAR DISEASES; CORONARY DISEASE; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY, AMBULATORY; FOLLOW-UP STUDIES; GENOTYPE; INTRAOPERATIVE COMPLICATIONS; MYOCARDIAL INFARCTION; POSTOPERATIVE COMPLICATIONS; PROPORTIONAL HAZARDS MODELS; RECEPTORS, ADRENERGIC; RESPIRATORY FUNCTION TESTS; RISK; SWITZERLAND; TREATMENT OUTCOME;

EID: 34250861243     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/01.anes.0000267530.62344.a4     Document Type: Article

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