Levofloxacin implants with predefined microstructure fabricated by three-dimensional printing technique

International Journal of Pharmaceutics

Volumn 339, Issue 1-2, 2007, Pages 33-38

  Huang, Weidong ^a   Zheng, Qixin ^b   Sun, Wangqiang ^a   Xu, Huibi ^a   Yang, Xiangliang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Conventional compression mold; Drug implant; Drug release in vitro; Levofloxacin (LVFX); Three dimensional (3D) printing

Indexed keywords

ACETONE; ALCOHOL; LEVOFLOXACIN; POLYLACTIC ACID;

ABSORPTION SPECTROPHOTOMETRY; ARTICLE; DRUG IMPLANT; DRUG STRUCTURE; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MORPHOLOGY; PARAMETER; PRIORITY JOURNAL; PULSATILE DRUG RELEASE; SCANNING ELECTRON MICROSCOPY; STEADY STATE; STRUCTURE ANALYSIS; TECHNIQUE; THREE DIMENSIONAL IMAGING;

DRUG IMPLANTS; MICROSCOPY, ELECTRON, SCANNING; OFLOXACIN; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 34250836847     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.02.021     Document Type: Article

References (22)

1. Achim G. Bioerodible implants with programmable drug release. J. Control Release 44 (1997) 271-281
2. Alekha K.D., and Greggrey C.C. Therapeutic applications of implantable drug delivery systems. J. Pharmacol. Toxicol. Methods 40 (1998) 1-12
3. Castro C., Sanchez E., Delgado A., Soriano I., Nunez P., Baro M., Perea, and Evora C. Ciprofloxacin implants for bone infection in vitro-in vivo characterization. J. Control Release 93 (2003) 341-354
4. Chein Y.W. Novel Drug Delivery Systems. second ed. (1992), Marcel Dekker Inc., New York, NY pp. 445-460
5. Cima, L.G., Cima, M.J., 1996. Preparation of medical devices by solid free-form fabrication methods. U.S. patent 5,490,962, 13, February.
6. Gabriel T.M., David G., and Scott J. Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures. Biomaterials 23 (2002) 1283-1293
7. Huang W.D., Sun W.Q., Zheng Q.X., Guo X.D., Yu D.G., Liu W., Xu H.B., and Yang X.L. Design and fabrication of drug delivery devices with complex architectures based on three-dimensional printing technique. J. Wuhan Univ. Technol.-Mater. Sci. Edit. 20 (2005) 80-82
8. Jill K.S., Susan L.R., Robert P., Scott C.B., Donald C.M., Matt C., Linda G.G., Lee K.L., and Anthony R. A three-dimensional osteochondral composite scaffold forarticular cartilage repair. Biomaterials 23 (2002) 4739-4751
9. Katsta W.E., Palazzolo R.D., Rowe C.W., Giritlioglu B., and Teung P. Oral dosage forms fabricated by three dimensional printing. J. Control Release 66 (2000) 1-9
10. Kim S.S., Utsunomiya H., Koski J.A., Wu B.M., Cima M.J., Sohn J., Mukai K., Griffith L.G., and Vacanti J.P. Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scoffold with intrinsic network of channels. Ann. Surg. 228 (1998) 8-13
11. Lam C.X.F., Mo X.M., Teoh S.H., and Hutmacher D.W. Scoffold development using 3D printing with a starch-based polymer. Mater. Sci. Eng. C 20 (2002) 49-56
12. Leong K.F., Cheah C.M., and Chua C.K. Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. Biomaterials 24 (2003) 2363-2378
13. Monkhouse, D., Yoo, J., Sherwood, J., Cima, M.J., Bornancini, E., 2003. Dosage forms exhibiting multi-phastic release kinetics and methods of manufacture thereof. U.S. patent 6,514,518 B2, 4 February.
14. Park A., Wu B., and Griffith L.G. Integration of surface modification and 3D fabrication techniques to prepare patterned poly (L-lactide) sbustrate allowing regionally selective cell adhesion. J. Biamater. Sci.-Polym. E 9 (1998) 89-110
15. Rowe C.W., Katsta W.E., Polazzolo R.D., Giritlioglu B., Teung P., and Cima M.J. Multimechanism oral dosage forms fabricated by three dimensional printing. J. Control Release 66 (2000) 11-17
16. Sachols E., Reis N., Ainsley C., Derby B., and Czernuszka J.T. Novel collagen scaffolds with prefined internal morphology made by solid freeform fabrication. Biomaterials 24 (2003) 1487-1497
17. Sarah L.T., and Tejal A.D. Microfabricated drug delivery systems: from particles to pores. Adv. Drug Deliv. Rev. 55 (2003) 315-328
18. Soriano I., and Evora C. Formulation of calcium phosphates/poly (d,l-lactide) blends containing gentamicin for bone implantation. J. Control Release 68 (2000) 121-234
19. Wu B.M., Borland S.W., Giordano R.A., Cima L.G., Sachs E.M., and Cima M.J. Solid free-form fabrication of drug delivery devicess. J. Control. Release 40 (1996) 77-87
20. Zeltinger J., Sheerwood J.K., Graham D.M., Mueller R., and Griffith L.G. Effects of pore size and void fraction on celluar adhesion, proliferation, and matrix deposition. Tisse Eng. 7 (2001) 557-572
21. Zheng Q.X., Guo X.D., and Du J.Y. Biodegradation of absorbable HA/dl-PLA composites in different environment. J. Wuhan Univ. Technol.-Mater. Sci. Edit. 17 (2002) 24-29
22. Zhou T.H., Lewis H., Foster R.E., and Schwendeman S.P. Development of a multiple-drug delivery implant for intraocular management of proliferative vitreoretinopathy. J. Control Release 55 (1998) 281-295