Facile synthetic route to enantiopure unsymmetric cis-2,5-disubstituted pyrrolidines

Chirality

Volumn 19, Issue 7, 2007, Pages 581-588

  Wang, Ping An ^a   Xu, Zheng Shuang ^b   Chen, Chun Feng ^b   Gao, Xu Guang ^b   Sun, Xiao Li ^a   Zhang, Sheng Yong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Chiral auxiliary; cis 2,5 disubstituted pyrrolidine; Enantiopure; Grignard reaction; Hydrogenolysis; X ray crystallographic analysis

Indexed keywords

ADIPIC ACID DERIVATIVE; ALPHA METHYLBENZYLAMINE; DIETHYL 2,5 DIBROMOADIPATE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; COLUMN CHROMATOGRAPHY; DIASTEREOISOMER; ENANTIOMER; GRIGNARD REACTION; PRIORITY JOURNAL; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRROLIDINES; STEREOISOMERISM;

EID: 34250832066     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20424     Document Type: Article

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