An alternative strategy for inhibiting multidrug-resistant mutants of the dimeric HIV-1 protease by targeting the subunit interface

Biochemical Society Transactions

Volumn 35, Issue 3, 2007, Pages 551-554

  Bannwarth, L ^a   Reboud Ravaux, M ^a  

^a INSTITUT JACQUES MONOD   (France)

Author keywords

AIDS; Dimerization inhibitor; HIV 1 protease; Lipopeptide; Molecular hairpin; Protein protein interaction

Indexed keywords

AMPRENAVIR; DIMER; GUANIDINE DERIVATIVE; HOMODIMER; LIPOPEPTIDE; MONOMER; NELFINAVIR; PEPTIDE DERIVATIVE; PROTEIN SUBUNIT; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; VIRUS PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; BETA SHEET; CONFERENCE PAPER; DIMERIZATION; DRUG INHIBITION; DRUG TARGETING; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MULTIDRUG RESISTANCE; MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

BINDING SITES; DIMERIZATION; DRUG RESISTANCE, MULTIPLE, VIRAL; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34250829125     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0350551     Document Type: Conference Paper

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