The autophagic pathway: A cell survival strategy against the bacterial pore-forming toxin Vibrio cholerae cytolysin

Autophagy

Volumn 3, Issue 4, 2007, Pages 363-365

  Saka, Héctor A ^a   Gutiérrez, Maximiliano G ^b   Bocco, José Luis ^a   Colombo, María I ^b  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Autophagy; Cell survival; Multivesicular bodies; Pore forming toxin; Vibrio cholerae cytolysin

Indexed keywords

CHOLERA TOXIN; CYTOLYSIN; EXOTOXIN;

ARTICLE; AUTOPHAGY; BACTERIAL VIRULENCE; CELL PROTECTION; CELL SURVIVAL; CELL VACUOLE; CHANNEL GATING; CYTOLYSIS; DEGRADATION; LYSOSOME; NONHUMAN; PROTEIN SECRETION; VIBRIO CHOLERAE;

BACTERIA (MICROORGANISMS); VIBRIO CHOLERAE;

EID: 34250820407     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.4159     Document Type: Article

References (30)

1. Faruque SM, Albert MJ, Mekalanos JJ. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev 1998; 62:1301-14.
2. Sack DA, Sack RB, Nair GB, Siddique AK. Cholera. Lancet 2004; 363:223-33.
3. Karaolis DK, Johnson JA, Bailey CC, Boedeker EC, Kaper JB, Reeves PR. A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains. Proc Natl Acad Sci USA 1998; 95:3134-9.
4. Honda T, Finkelstein RA. Purification and characterization of a hemolysin produced by Vibrio cholerae biotype El Tor: Another toxic substance produced by cholera vibrios. Infect Immun 1979; 26:1020-7.
5. Heidelberg JF, Eisen JA, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Umayam L, Gill SR, Nelson KE, Read TD, Tettelin H, Richardson D, Ermolaeva MD, Vamathevan J, Bass S, Qin H, Dragoi I, Sellers P, McDonald L, Utterback T, Fleishmann RD, Nierman WC, White O, Salzberg SL, Smith HO, Colwell RR, Mekalanos JJ, Venter JC, Fraser CM. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 2000; 406:477-83.
6. Ichinose Y, Yamamoto K, Nakasone N, Tanabe MJ, Takeda T, Miwatani T, Iwanaga M. Enterotoxicity of El Tor-like hemolysin of non-O1 Vibrio cholerae. Infect Immun 1987; 55:1090-3.
7. Figueroa-Arredondo P, Heuser JE, Akopyants NS, Morisaki JH, Giono-Cerezo S, Enriquez-Rincon F, Berg DE. Cell vacuolation caused by Vibrio cholerae hemolysin. Infect Immun 2001; 69:1613-24.
8. Fullner KJ, Boucher JC, Hanes MA, Haines IIIrd GK, Meehan BM, Walchle C, Sansonetti PJ, Mekalanos JJ. The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model. J Exp Med 2002; 195:1455-62.
9. Pichel M, Rivas M, Chinen I, Martin F, Ibarra C, Binsztein N. Genetic diversity of Vibrio cholerae O1 in Argentina and emergence of a new variant. J Clin Microbiol 2003; 41:124-34.
10. Shintani T, Klionsky DJ. Autophagy in health and disease: A double-edged sword. Science 2004; 306:990-5.
11. Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290:1717-21.
12. Mizushima N, Yamamoto A, Hatano M, Kobayashi Y, Kabeya Y, Suzuki K, Tokuhisa T, Ohsumi Y, Yoshimori T. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol 2001; 152:657-68.
13. Kirkegaard K, Taylor MP, Jackson WT. Cellular autophagy: Surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol 2004; 2:301-14.
14. Levine B. Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense. Cell 2005; 120:159-62.
15. Levine B, Klionsky DJ. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6:463-77.
16. Marino G, Lopez-Otin C. Autophagy: Molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci 2004; 61:1439-54.
17. Mizushima N, Ohsumi Y, Yoshimori T. Autophagosome formation in mammalian cells. Cell Struct Funct 2002; 27:421-9.
18. Gutierrez MG, Vazquez CL, Munafo DB, Zoppino FC, Beron W, Rabinovitch M, Colombo MI. Autophagy induction favours the generation and maturation of the Coxiella-replicative vacuoles. Cell Microbiol 2005; 7:981-93.
19. Gutierrez MG, Saka HA, Chinen I, Zoppino FC, Yoshimori T, Bocco JL, Colombo MI. Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc Natl Acad Sci USA 2007; 104:1829-34.
20. Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Aurophagy 2005; 1:84-91.
21. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720-8.
22. Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J Cell Biol 1992; 119:301-11.
23. Uttenweiler A, Schwarz H, Mayer A. Microautophagic vacuole invagination requires calmodulin in a Ca2+-independent function. J Biol Chem 2005; 280:33289-97.
24. Gruenberg J, Stenmark H. The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol 2004; 5:317-23.
25. Katzmann DJ, Odorizzi G, Emr SD. Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol 2002; 3:893-905.
26. Futter CE, Pearse A, Hewlett LJ, Hopkins CR. Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J Cell Biol 1996; 132:1011-23.
27. Kunz JB, Schwarz H, Mayer A. Determination of four sequential stages during microautophagy in vitro. J Biol Chem 2004; 279:9987-96.
28. Uttenweiler A, Schwarz H, Neumann H, Mayer A. The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 2007; 18:166-75.
29. Pantano S, Montecucco C. A molecular model of the Vibrio cholerae cytolysin transmembrane pore. Toxicon 2006; 47:35-40.
30. Moschioni M, Tombola F, de Bernard M, Coelho A, Zitzer A, Zoratti M, Montecucco C. The Vibrio cholerae haemolysin anion channel is required for cell vacuolation and death. Cell Microbiol 2002; 4:397-409.