Synthesis of 2-substituted-5-halo-2,3-dihydro-4(H)-pyrimidin-4-ones and their derivatization utilizing the sonogashira coupling reaction in the enantioselective synthesis of α-substituted β-amino acids

Journal of Organic Chemistry

Volumn 72, Issue 13, 2007, Pages 4822-4825

  Díaz Sánchez, Blanca R ^a   Iglesias Arteaga, Martín A ^a,b   Melgar Fernández, Roberto ^a   Juaristi, Eusebio ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; DERIVATIVES; ENANTIOSELECTIVITY; HYDROGENATION; HYDROLYSIS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

DECARBOXYLATION; SONOGASHIRA COUPLING REACTION; TERMINAL ALKYNES;

AMINO ACIDS;

1 BENZOY1 2 ISOPROPY1 5 A1KYNYL 2,3 DIHYDRO 4(H) PYRIMIDIN 4 ONE DERIVATIVE; 2,3 DIHYDRO 4(H) PYRIMIDIN-4-ONE DERIVATIVE; 4 PYRIMIDINONE DERIVATIVE; 6 CARBOXYPERHYDROPYRIMIDIN 4 ONE DERIVATIVE; ALKYNE DERIVATIVE; BETA AMINO ACID; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; BROMINATION; CHIRALITY; DECARBOXYLATION; DERIVATIZATION; ENANTIOSELECTIVITY; HALOGENATION; HYDROGENATION; HYDROLYSIS; IODINATION; ONE POT SYNTHESIS; SONOGASHIRA REACTION; SUBSTITUTION REACTION;

EID: 34250817420     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0705115     Document Type: Article

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