Controlled delivery of ganciclovir to the retina with drug-loaded poly(D,L-lactide-co-glycolide) (PLGA) microspheres dispersed in PLGA-PEG-PLGA gel: A novel intravitreal delivery system for the treatment of cytomegalovirus retinitis

Journal of Ocular Pharmacology and Therapeutics

Volumn 23, Issue 3, 2007, Pages 264-274

  Duvvuri, Sridhar ^a   Janoria, Kumar G ^b   Pal, Dhananjay ^b   Mitra, Ashim K ^b  

^a WYETH RESEARCH   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; MACROGOL; MICROSPHERE; POLYGLACTIN; POLYMER; RESOMER; SOLVENT;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DISPERSION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG MIXTURE; DRUG RELEASE; ENCAPSULATION; EVAPORATION; GEL; MALE; MICRODIALYSIS; MOLECULAR WEIGHT; NONHUMAN; RETINITIS; STEADY STATE;

ANIMALS; ANTIVIRAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CYTOMEGALOVIRUS RETINITIS; DELAYED-ACTION PREPARATIONS; GANCICLOVIR; GELS; HALF-LIFE; LACTIC ACID; MALE; MICRODIALYSIS; MICROSPHERES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS; RABBITS; RETINA; TEMPERATURE; TISSUE DISTRIBUTION; VITREOUS BODY;

EID: 34250802004     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2006.132     Document Type: Article

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