Anesthesia increases in vivo N-([18F]fluoroethyl)piperidinyl benzilate binding to the muscarinic cholinergic receptor

Nuclear Medicine and Biology

Volumn 34, Issue 5, 2007, Pages 479-482

  Kilbourn, Michael R ^a   Ma, Bing ^a   Butch, Elizabeth R ^a   Quesada, Carole ^a   Sherman, Phillip S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Anesthesia; Emission computed; Isoflurane; Phenserine; Tomography

Indexed keywords

CHOLINESTERASE INHIBITOR; ISOFLURANE; MUSCARINIC RECEPTOR; N FLUOROETHYLPIPERIDINYLBENZILATE F 18; PENTOBARBITAL; PHENSERINE; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; BRAIN CORTEX; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORPUS STRIATUM; DISTRIBUTION VOLUME; DRUG EFFECT; DRUG RECEPTOR BINDING; EXPERIMENTAL RAT; HIPPOCAMPUS; IN VIVO STUDY; LIGAND BINDING; MALE; NONHUMAN; RAT; STATISTICAL SIGNIFICANCE;

ANESTHETICS, INHALATION; ANIMALS; BENZILATES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORINE RADIOISOTOPES; HYPNOTICS AND SEDATIVES; ISOFLURANE; MALE; METABOLIC CLEARANCE RATE; PENTOBARBITAL; PIPERIDINES; PROTEIN BINDING; RADIOPHARMACEUTICALS; RATS; TISSUE DISTRIBUTION;

EID: 34250786313     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2007.04.008     Document Type: Article

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