Pet study of the [11C]raclopride binding in the striatum of the awake cat: Effects of anaesthetics and role of cerebral blood flow

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 30, Issue 1, 2003, Pages 141-148

  Hassoun, Wadad ^a   Le Cavorsin, Marion ^b   Ginovart, Nathalie ^a   Zimmer, Luc ^a   Gualda, Veronique ^a   Bonnefoi, Frederic ^a   Leviel, Vincent ^b  

^a CERMEP IMAGERIE DU VIVANT   (France)

^b Laboratoire de Physiologie Int&EACUTE grative Cellulaire et Mol&EACUTE culaire Villeurbanne   (France)

Author keywords

Anaesthesia; Animal; D2 receptors; Positron emission tomography

Indexed keywords

ANESTHETIC AGENT; CARBON 11; HALOTHANE; KETAMINE; OXYGEN 15; RACLOPRIDE; RADIOLIGAND; WT1 PROTEIN; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; CAT; CEREBELLUM; CORPUS STRIATUM; DRUG BINDING; DRUG EFFECT; EVALUATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; WAKEFULNESS; ANIMAL; BRAIN CIRCULATION; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; MALE; METABOLISM; PHYSIOLOGY; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; VASCULARIZATION;

ANESTHETICS; ANIMALS; CATS; CEREBELLUM; CEREBROVASCULAR CIRCULATION; CORPUS STRIATUM; HALOTHANE; KETAMINE; MALE; RACLOPRIDE; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, EMISSION-COMPUTED; WAKEFULNESS;

EID: 0037531690     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-002-0904-4     Document Type: Article

References (48)

1. 11C]raclopride displacement and PET. Neurology 1996; 46:1430-1436.
2. Laruelle M, Iyer RN, Al-Tikriti MS, Zea-Ponce Y, Malisson R, Zoghbi SS, Baldwin RM, Kung HF, Charney DS, Hoffer PB, Innis RB. Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates. Synapse 1997; 25:1-14.
3. Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM. Evidence for striatal dopamine release during a video game. Nature 1998; 393:266-268.
4. 11C]raclopride binding to D2-dopamine receptors in the monkey brain. Synapse 1997; 25:321-325.
5. 11C]raclopride: optimization and signal-to-noise considerations. J Nucl Med 2000; 41:522-530.
6. Fisher RE, Morris ED, Alpert NM, Fischman AJ. In vivo imaging of neuromodulatory synaptic transmission using PET: a review of relevant neurophysiology. Hum Brain Mapping 1995; 3:24-34.
7. Laruelle M. Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J Cereb Blood Flow Metab 2000; 20:423-451.
8. Friston KJ, Malizia AL, Wilson S, Cunningham VJ, Jones T, Nutt DJ. Analysis of dynamic radioligand displacement or "activation" studies. J Cereb Blood Flow Metab 1997; 17:80-93.
9. Dewey SL, Smith GS, Logan J, Alexoff D, Ding YS, King P, Pappas N, Brodie JD, Ashby CR Jr. Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis. J Neurosci 1995; 15:821-829.
10. 11C]raclopride binding with no alterations in static dopamine concentrations in the striatal extracellular fluid in the monkey brain: multi-parametric PET studies combined with microdialysis analysis. Synapse 2000; 37:95-103.
11. 18F-MPPF in the rat hippocampus: Kinetic β measurements combined with microdialysis. J. of Neurochemistry 2002; 80:278-286.
12. 11C-raclopride is altered by drugs that modify synaptic dopamine levels. Synapse 1993; 13:350-356.
13. Hartvig P, Torstenson R, Tedroff J, Watanabe Y, Fasth KJ, Bjurling P Langstrom B. Amphetamine effects on dopamine release and synthesis rate studied in the rhesus monkey brain by positron emission tomography. J Neural Transm 1997; 104:329-339.
14. 11C]raclopride binding in anesthetized cats. Neuropsychopharmacology 2002; 27: 72-84.
15. Zetterstrom T, Sharp T, Ungerstedt U. Further evaluation of the mechanism by which amphetamine reduces striatal dopamine metabolism: a brain dialysis study. Eur J Pharmacol 1986; 132:1-9.
16. Fink-Jensen A, Ingwersen SH, Nielsen PG, Hansen L, Nielsen EB Hansen AJ. Halothane anesthesia enhances the effect of dopamine uptake inhibition on interstitial levels of striatal dopamine. Naunyn-Schmiedebergs Arch Pharmacol 1994; 350: 239-244.
17. 11C]raclopride. J Nucl Med 2002; 43:227-233.
18. Wreggett KA, Seeman P. Agonist high and low affinity states of the D2 dopamine receptor in calf brain. Partial conversion by guanine nucleotide. Mol Pharmacol 1984; 25:10-17.
19. Martin DC, Dennison RL, Introna RP, Aronstam RS. Influence of halothane on the interaction of serotonin1 and adenosinel receptors with G protein in rat brain membranes. Biochem Pharmacol 1991; 42:1313-1316.
20. Brix G, Zaers J, Adam LE, Bellemann ME, Ostertag H, Trojan H, Haberkorn U, Doll J, Oberdorfer F, Lorenz WJ. Performance evaluation of a whole-body PET scanner using the NEMA protocol. National Electrical Manufacturers Association. J Nucl Med 1997; 38:1614-1623.
21. Halldin C. Radioligands for dopamine receptor PET studies: benzamides and ligands for dopamine D-1 receptors. In: Baron JC, Comar D, Farde L, Martinot JL, Mazoyer B, eds. Brain dopaminergic systems: imaging with positron tomography. Dordrecht: Kluwer Academic; 1991:23-38.
22. 18F]MPPF, a fluoro analog of WAY-100635 for visualization of 5HT1A receptors. Synapse 2000; 35:192-200.
23. Goffart L, Pelisson D. Orienting gaze shifts during muscimol inactivation of caudal fastigial nucleus in the cat. I. Gaze dysmetria. J Neurophysiol 1998; 79:1942-1958.
24. Jasper HH, Ajmone-Marsan C. In: A stereotaxic atlas of the diencephalon of the cat. The National Research Council of Canada. Ottawa, Canada, 1954.
25. 11C]raclopride studies. J Cereb Blood Flow Metab 1996; 16:42-52.
26. Sakiyama Y, Sato A, Senda M, Ishiwata K, Toyama H, Schmidt RF. Positron emission tomography reveals changes in global and regional cerebral blood flow during noxious stimulation of normal and inflamed elbow joints in anesthetized cats. Exp Brain Res 1998; 118:439-446.
27. 18F]haloperidol from the chloro-precursor and its applications in PET imaging of a cat's brain. Appl Radiat Isot 1997; 48:1179-1185.
28. 11C]raclopride in man. Synapse 1995; 20:200-208.
29. 11C]raclopride PET. Synapse 1998; 28:66-70.
30. 11C-raclopride against anesthetics in rhesus monkey brain. J Neural Transm 1995; 100: 147-151.
31. 11C]Nmethylspiperone, in rats. Ann Nucl Med 1999; 13:161-167.
32. Paut O, Bissonnette B. Effect of halothane on the cerebral circulation in young children: a hysteresis phenomenon. Anaesthesia 2001; 56:360-365.
33. Brussel T, Fitch W, Brodner G, Arendt I, Van Aken H. Effects of halothane in low concentrations on cerebral blood flow, cerebral metabolism, and cerebrovascular autoregulation in the baboon. Anesth Analg 1991; 73:758-764.
34. Hansen TD, Warner DS, Todd MM, Vust LJ. Effects of nitrous oxide and volatile anaesthetics on cerebral blood flow. Br JAnaesth 1989; 63:290-295.
35. 2-reactivity during craniotomy for supratentorial cerebral tumours in halothane anaesthesia. A dose-response study. Acta Anaesthesiol Scand 1987; 31:454-457.
36. 2+ signaling and transmitter release in a neural cell line. Anesthesiology 1991; 74:309-319.
37. Salord F, Keita H, Lecharny JB, Henzel D, Desmonts JM, Mantz J. Halothane and isoflurane differentially affect the regulation of dopamine and gamma-aminobutyric acid release mediated by presynaptic acetylcholine receptors in the rat striatum. Anesthesiology 1997; 86:632-641.
38. Mantz J, Varlet C, Lecharny JB, Henzel D, Lenot P, Desmont JM. Effects of volatile anesthetics, thiopental, and ketamine on spontaneous and depolarization-evoked dopamine release from striatal synaptosomes in the rat. Anesthesiology 1994; 80:352-363.
39. Stahle L, Collin AK, Ungerstedt U. Effects of halothane anaesthesia on extracellular levels of dopamine, dihydroxyphenylacetic acid, homovanillic acid and 5-hydroxy indolacetic acid in rat striatum: a microdialysis study. Naunyn-Schmiedebergs Arch Pharmacol 1990; 342:136-140.
40. Tsukada H, Nishiyama S, Kakiuchi T, Ohba H, Sato K, Harada N, Nakanishi S. Isoflurane anesthesia enhances the inhibitory effects of cocaine and GBR12909 on dopamine transporter: PET studies in combination with microdialysis in the monkey brain. Brain Res 1999; 849:85-96.
41. el Maghrabi EA, Eckenhoff RG. Inhibition of dopamine transport in rat brain synaptosomes by volatile anesthetics. Anesthesiology 1993; 78:750-756.
42. Bacopoulos NG, Redmond DE, Roth RH. Serotonin and dopamine metabolites in brain regions and cerebrospinal fluid of a primate species: effects of ketamine and fluphenazine. J Neurochem 1979; 32:1215-1218.
43. Koshikawa N, Tomiyama K, Omiya K, Kobayashi M. Ketamine anesthesia has no effect on striatal dopamine metabolism in rats. Brain Res 1988; 444:394-396.
44. Mc Cowin TJ, Mueller RA, Breese GR. Effects of anesthetics and electrical stimulation on nigrostriatal dopaminergic neurons. J Pharm Exp Ther 1983; 224:489-493.
45. Mereu G, Fanni B, Gessa GL. General anesthetics prevent dopamine neuron stimulation by neuroleptics. In: Usdin E, Carlsson A, Dahlström A, Engel J, eds. Catecholamines. Part B. Neuropharmacology and central nervous system-theoretical aspects. New York: Alan Liss; 1984:353-358.
46. Breier A, Adler CM, Weisenfeld N, Su TP, Elman I, Picken L, Malhotra AK, Pickar D. Effects of NMDA antagonism on striatal dopamine release in healthy subjects: Application of a novel PET approach. Synapse 1998; 29:142-147.
47. Verma A, Moghaddam B. NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine. J Neurosci 1996; 16:373-379.
48. Laruelle M, Abi-Dargham A, van Dyck CH, Rosenblatt W, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Charney DS, Hoffer PB, Kung HF, Innis RB. SPECT imaging of striatal dopamine release after amphetamine challenge. J Nucl Med 1998; 36:1182-1190.