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AAPS Journal
Volumn 9, Issue 2, 2007, Pages
Partial derivative - Based sensitivity analysis of models describing target-mediated drug disposition
Author keywords

Equilibrium dissociation constant; Nonlinear pharmacokinetics; Quasiequilibrium models; Receptor internalization
Indexed keywords

LEUKEMIA INHIBITORY FACTOR;
EID: 34250772444     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/aapsj0902020     Document Type: Article
Times cited : (29)
References (14)
  • 1
    • 0027998106 scopus 로고
    • Pharmacologic target-mediated drug disposition
    • Levy G . Pharmacologic target-mediated drug disposition. Clin Pharmacol Ther. 1994; 56: 248-252.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 248-252
    • Levy, G.1
  • 2
    • 0035730322 scopus 로고    scopus 로고
    • General pharmacokinetic model for drugs exhibiting target-mediated drug disposition
    • Mager DE, Jusko WJ. General pharmacokinetic model for drugs exhibiting target-mediated drug disposition. J Pharmacokinet Pharmacodyn. 2001; 28: 507-532.
    • (2001) J Pharmacokinet Pharmacodyn , vol.28 , pp. 507-532
    • Mager, D.E.1    Jusko, W.J.2
  • 3
    • 33646901012 scopus 로고    scopus 로고
    • Target-mediated drug disposition and dynamics
    • Mager DE. Target-mediated drug disposition and dynamics. Biochem Pharmacol. 2006; 72: 1-10.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1-10
    • Mager, D.E.1
  • 4
    • 25144510899 scopus 로고    scopus 로고
    • Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition
    • Mager D, Krzyzanski W. Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition. Pharm Res. 2005; 22: 1589-1596.
    • (2005) Pharm Res , vol.22 , pp. 1589-1596
    • Mager, D.1    Krzyzanski, W.2
  • 6
    • 0028944480 scopus 로고
    • Effect of parameter variability on physiologically-based pharmacokinetic model predicted drug concentrations
    • Varkonyi P, Bruckner JV, Gallo JM. Effect of parameter variability on physiologically-based pharmacokinetic model predicted drug concentrations. J Pharm Sci. 1995; 84: 381-384.
    • (1995) J Pharm Sci , vol.84 , pp. 381-384
    • Varkonyi, P.1    Bruckner, J.V.2    Gallo, J.M.3
  • 7
    • 0028501607 scopus 로고
    • A review of techniques for parameter sensitivity analysis of environmental models
    • Hamby DM. A review of techniques for parameter sensitivity analysis of environmental models. Environ Monit Assess. 1994; 32: 135-154.
    • (1994) Environ Monit Assess , vol.32 , pp. 135-154
    • Hamby, D.M.1
  • 8
    • 0033840260 scopus 로고    scopus 로고
    • Sensitivity analysis of pharmacokinetic parameters in onecompartment models
    • Wu G. Sensitivity analysis of pharmacokinetic parameters in onecompartment models. Pharmacol Res. 2000; 41: 445-453.
    • (2000) Pharmacol Res , vol.41 , pp. 445-453
    • Wu, G.1
  • 9
    • 0033292350 scopus 로고    scopus 로고
    • Sensitivity analysis of pharmacokinetic and pharmacodynamic systems, I: A structural approach to sensitivity analysis of physiologically based pharmacokinetic models
    • Nestorov IA. Sensitivity analysis of pharmacokinetic and pharmacodynamic systems, I: a structural approach to sensitivity analysis of physiologically based pharmacokinetic models. J Pharmacokinet Biopharm. 1999; 27: 577-596.
    • (1999) J Pharmacokinet Biopharm , vol.27 , pp. 577-596
    • Nestorov, I.A.1
  • 10
    • 0031412578 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling of a homologous series of barbiturates in the rat: A sensitivity analysis
    • Nestorov IA, Aarons LJ, Rowland M. Physiologically based pharmacokinetic modeling of a homologous series of barbiturates in the rat: a sensitivity analysis. J Pharmacokinet Biopharm. 1997; 25: 413-447.
    • (1997) J Pharmacokinet Biopharm , vol.25 , pp. 413-447
    • Nestorov, I.A.1    Aarons, L.J.2    Rowland, M.3
  • 11
    • 0026004357 scopus 로고
    • Sensitivity analysis for physiologically based pharmacokinetic models
    • Hetrick DM, Jarabek AM, Travis CC. Sensitivity analysis for physiologically based pharmacokinetic models. J Pharmacokinet Biopharm. 1991; 19: 1-20.
    • (1991) J Pharmacokinet Biopharm , vol.19 , pp. 1-20
    • Hetrick, D.M.1    Jarabek, A.M.2    Travis, C.C.3
  • 12
    • 0008762412 scopus 로고
    • A new generalized nonlinear pharmacokinetic model and its implications
    • Wagner JG, ed, Hamilton, IL: Drug Intelligence Publications;
    • Wagner JG. A new generalized nonlinear pharmacokinetic model and its implications. In: Wagner JG, ed. Biopharmaceutics and Relevant Pharmacokinetics. Hamilton, IL: Drug Intelligence Publications; 1971:302-317.
    • (1971) Biopharmaceutics and Relevant Pharmacokinetics , pp. 302-317
    • Wagner, J.G.1
  • 13
    • 0028836085 scopus 로고
    • A comparison of sensitivity analysis techniques
    • Hamby DM. A comparison of sensitivity analysis techniques. Health Phys. 1995; 68: 195-204.
    • (1995) Health Phys , vol.68 , pp. 195-204
    • Hamby, D.M.1
  • 14
    • 0033079533 scopus 로고    scopus 로고
    • A quantitative model-independent method for global sensitivity analysis of model output
    • Saltelli A, Tarantola S, Chan KPS. A quantitative model-independent method for global sensitivity analysis of model output. Technometrics. 1999; 41: 39-56.
    • (1999) Technometrics , vol.41 , pp. 39-56
    • Saltelli, A.1    Tarantola, S.2    Chan, K.P.S.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.