Expression of the carbohydrate tumour marker SLeX, SLeA (CA19-9), LeY and Thomsen-Friedenreich (TF) antigen on normal squamous epithelial tissue of the penis and vagina

Anticancer Research

Volumn 27, Issue 4 A, 2007, Pages 1981-1988

  Wiest, Irmi ^a   Schulze, Sandra ^a   Kuhn, Christina ^a   Seliger, Christian ^b   Hausmann, Roland ^b   Betz, Peter ^b   Mayr, Doris ^a   Friese, Klaus ^a   Jeschke, Udo ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Carbohydrate tumour marker; LeY; SLeA (CA19 9); SLeX; Thomsen Friedenreich (TF) antigen

Indexed keywords

BLOOD GROUP ANTIGEN; CA 19-9 ANTIGEN; CARBOHYDRATE ANTIGEN; LEWIS Y ANTIGEN; SIALYL LEWIS A ANTIGEN; SIALYL LEWIS X ANTIGEN; THOMSEN FRIEDENREICH ANTIGEN; TUMOR ANTIGEN; TUMOR MARKER; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PENIS GLANS; PRIORITY JOURNAL; SCORING SYSTEM; SQUAMOUS EPITHELIUM; VAGINA EPITHELIUM;

ANTIGENS, NEOPLASM; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CA-19-9 ANTIGEN; EPITHELIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LEWIS BLOOD-GROUP SYSTEM; MALE; OLIGOSACCHARIDES; PENIS; TUMOR MARKERS, BIOLOGICAL; VAGINA;

EID: 34250745632     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (38)

1. Uchimura K, Kadomatsu K, El-Fasakhany FM, Singer MS, Izawa M, Kannagi R, Takeda N, Rosen SD and Muramatsu T: N-acetylglucosamine 6-O sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. J Biol Chem 279: 35001-35008, 2004.
2. Kannagi R: Regulatory roles of carbohydrate ligands for selectins in the homing of lymphocytes. Curr Opin Struct Biol 12: 599-608, 2002.
3. Foxall C, Watson SR, Dowbenko D, Fennie C, Lasky LA, Kiso M, Hasegawa A, Asa D and Brandley BK: The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide. J Cell Biol 117: 895-902, 1992.
4. Paavonen T and Renkonen R: Selective expression of sialyl-Lewis x and Lewis a epitopes, putative ligands for L-selectin, on peripheral lymph-node high endothelial venules. Am J Pathol 141: 1259-1264, 1992.
5. Monzavi-Karbassi B, Whitehead TL, Jousheghany F, Artaud C, Hennings L, Shaaf S, Slaughter A, Korourian S, Kelly T, Blaszczyk-Thurin M and Kieber-Emmons T: Deficiency in surface expression of E-selectin ligand promotes lung colonization in a mouse model of breast cancer. Int J Cancer 117: 398-408, 2005.
6. Kannagi R, Izawa M, Koike T, Miyazaki K and Kimura N: Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis. Cancer Sci 95: 377-384, 2004.
7. Kannagi R: Molecular mechanism for cancer-associated induction of sialyl Lewis X and sialyl Lewis A expression - the Warburg effect revisited. Glycoconj J 20: 353-364, 2004.
8. Jeschke U, Mylonas I, Richter DU, Streu A, Muller H, Briese V and Friese K: Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro. Gynecol Obstet Invest 58: 207-211, 2004.
9. Jeschke U, Gundel G, Muller H, Richter DU, Streu A, Briese V, Mylonas I, Friese K and Unverzagt C: N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro. J Perinat Med 32: 248-253, 2004.
10. Lowe JB: Selectin ligands, leukocyte trafficking, and fucosyltransferase genes. Kidney Int 51: 1418-1426, 1997.
11. Kuijpers TW: Terminal glycosyltransferase activity: a selective role in cell adhesion. Blood 81: 873-882, 1993.
12. Shur BD: Embryonal carcinoma cell adhesion: the role of surface galactosyltransferase and its 90K lactosaminoglycan substrate. Dev Biol 99: 360-372, 1983.
13. Wakabayashi M, Shiro T, Seki T, Nakagawa T, Itoh T, Imamura M, Shiozaki Y, Inoue K and Okamura A: Lewis Y antigen expression in hepatocellular carcinoma. An immunohistochemical study. Cancer 75: 2827-2835, 1995.
14. Springer GF: T and Tn, general carcinoma autoantigens. Science 224: 1198-1206, 1984.
15. Cao Y, Stosiek P, Springer GF and Karsten U: Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study. Histochem Cell Biol 106: 197-207, 1996.
16. Barr N, Taylor CR, Young T and Springer GF: Are pancarcinoma T and Tn differentiation antigens? Cancer 64: 834-841, 1989.
17. van Rooijen JJ, Jeschke U, Kamerling JP and Vliegenthart JF: Expression of N-linked sialyl Le(x) determinants and O-glycans in the carbohydrate moiety of human amniotic fluid transferrin during pregnancy. Glycobiology 8: 1053-1064, 1998.
18. Streu A, Jeschke U, Richter DU, Muller H, Briese V and Friese K: Human amniotic fluid transferrin stimulates progesterone production by human trophoblast cells in vitro. Zentralbl Gynakol 122: 407-412, 2000.
19. Oehninger S, Patankar M, Seppala M and Clark GF: Involvement of selectin-like carbohydrate binding specificity in human gamete interaction. Andrologia 30: 269-274, 1998.
20. Jeschke U, Mylonas I, Shabani N, Kunert-Keil C, Schindlbeck C, Gerber B and Friese K: Expression of sialyl Lewis X, sialyl Lewis A, E-cadherin and cathepsin-D in human breast cancer: immunohistochemical analysis in mammary carcinoma in situ, invasive carcinomas and their lymph node metastasis. Anticancer Res 25: 1615-1622, 2005.
21. Mylonas I, Makovitzky J, Vogel M, Shabani N, Jeschke U and Friese K: Expression of inhibin/activin subunits, sialyl-Lewis A (CA 19-9, sLea) and sialyl-Lewis X (sLex) carbohydrate antigens in a hydatidiform mole with persistent polymorphic trophoblastic hyperplasia. Anticancer Res 25: 1725-1730, 2005.
22. Mylonas I, Makovitzky J, Richter DU, Jeschke U, Briese V and Friese K: Expression of the inhibin-alpha subunit in normal, hyperplastic and malignant endometrial tissue: an immunohistochemical analysis. Gynecol Oncol 93: 92-97, 2004.
23. Munro JM, Lo SK, Corless C, Robertson MJ, Lee NC, Barnhill RL, Weinberg DS and Bevilacqua MP: Expression of sialyl-Lewis X, an E-selectin ligand, in inflammation, immune processes, and lymphoid tissues. Am J Pathol 141: 1397-1408, 1992.
24. Imai Y, Lasky LA and Rosen SD: Further characterization of the interaction between L-selectin and its endothelial ligands. Glycobiology 2: 373-381, 1992.
25. Green PJ, Tamatani T, Watanabe T, Miyasaka M, Hasegawa A, Kiso M, Yuen CT, Stoll MS and Feizi T: High affinity binding of the leucocyte adhesion molecule L-selectin to 3′-sulphated-Le(a) and -Le(x) oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides. Biochem Biophys Res Commun 188: 244-251, 1992.
26. Erbe DV, Wolitzky BA, Presta LG, Norton CR, Ramos RJ, Burns DK, Rumberger JM, Rao BN, Foxall C, Brandley BK et al: Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion. J Cell Biol 119: 215-227, 1992.
27. Phillips ML, Nudelman E, Gaeta FC, Perez M, Singhal AK, Hakomori S and Paulson JC: ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. Science 250: 1130-1132, 1990.
28. Hayashi M, Tanaka M, Itoh M and Miyauchi H: A Convenient and efficient synthesis of SLeX analogs. J Org Chem 61: 2938-2945, 1996.
29. Stahn R, Schafer H, Kernchen F and Schreiber J: Multivalent sialyl Lewis x ligands of definite structures as inhibitors of E-selectin mediated cell adhesion. Glycobiology 8: 311-319, 1998.
30. Stahn R, Goletz S, Wilmanowski R, Wang X, Briese V, Friese K and Jeschke U: Human chorionic gonadotropin (hCG) as inhibitior of E-selectin-mediated cell adhesion. Anticancer Res 25: 1811-1816, 2005.
31. Holgersson J, Breimer ME and Samuelsson BE: Basic biochemistry of cell surface carbohydrates and aspects of the tissue distribution of histo-blood group ABH and related glycosphingolipids. APMIS Suppl 27: 18-27, 1992.
32. Henry S, Oriol R and Samuelsson B: Lewis histo-blood group system and associated secretory phenotypes. Vox Sang 69: 166-182, 1995.
33. Springer GF, Desai PR, Murthy MS and Scanlon EF: Human carcinoma-associated precursor antigens of the NM blood group system. J Surg Oncol 11: 95-106, 1979.
34. Jeschke U, Richter DU, Reimer T, Bergemann C, Briese V, Karsten U, Mylonas I, Kupka MS, Wiest I and Friese K: Glycodelin A and differentiation of first trimester trophoblast cells in vitro. Arch Gynecol Obstet 272: 151-159, 2005.
35. Jeschke U, Reimer T, Bergemann C and Wiest I, Schulze S, Friese K and Walzel H: Binding of galectin-1 (gal-1) on trophoblast cells and inhibition of hormone production of trophoblast tumor cells in vitro by gal-1. Histochem Cell Biol 121: 501-508, 2004.
36. Jeschke U, Richter DU, Hammer A, Briese V, Friese K and Karsten U: Expression of the Thomsen-Friedenreich antigen and of its putative carrier protein mucin 1 in the human placenta and in trophoblast cells in vitro. Histochem Cell Biol 117: 219-226, 2002.
37. Richter DU, Jeschke U, Makovitzky J, Goletz S, Karsten U, Briese V and Friese K: Expression of the Thomsen-Friedenreich (TF) antigen in the human placenta. Anticancer Res 20: 5129-5133, 2000.
38. Richter DU, Jeschke U, Bergemann C, Makovitzky J, Luthen F, Karsten U and Briese V: Expression of the Thomsen-Friedenreich (TF) tumor antigen in human abort placentas. Anticancer Res 25: 1675-1678, 2005.