Expression of the Thomsen-Friedenreich (TF) tumor antigen in human abort placentas

Anticancer Research

Volumn 25, Issue 3 A, 2005, Pages 1675-1678

  Richter, Dagmar Ulrike ^a   Jeschke, U ^b   Bergemann, C ^a   Makovitzky, J ^a   Luthen F ^a   Karsten, U ^c   Briese, V ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Abort placenta; Thomsen Friedenreich; Tumor antigen

Indexed keywords

CYTOKERATIN 7; EPITOPE; GALACTOSE; GALACTOSE BETA 1,3 N ACETYLGALACTOSE; MUCIN 1; THOMSEN FRIEDENREICH ANTIGEN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ABORTION; ANTIGEN EXPRESSION; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DECIDUA; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LASER MICROSCOPY; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY; SYNCYTIOTROPHOBLAST; SYNCYTIUM; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

ABORTION, INDUCED; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; PLACENTA;

EID: 21244499373     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. Springer GF: T and Tn, general carcinoma autoantigens. Science 224: 1198-1206, 1984.
2. Cao Y, Stosiek P, Springer GF and Karsten U: Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study. Histochem Cell Biol 106: 197-207, 1996.
3. Barr N, Taylor CR, Young T and Springer GF: Are pancarcinoma T and Tn differentiation antigens? Cancer 64: 834-841, 1989.
4. Richter DU, Jeschke U, Makovitzky J, Goletz S, Karsten U, Briese V and Friese K: Expression of the Thomsen-Friedenreich (TF) antigen in the human placenta. Anticancer Res 20: 5129-5133, 2000.
5. Jeschke U, Richter DU, Hammer A, Briese V, Friese K and Karsten U: Expression of the Thomsen-Friedenreich antigen and of its putative carrier protein mucin 1 in the human placenta and in trophoblast cells in vitro. Histochem Cell Biol 117: 219-226, 2002.
6. Karsten U, Butschak G, Cao YI, Goletz S and Hanisch FG: A new monoclonal antibody (A78-G/A7) to the Thomsen-Friedenreich pan-tumor antigen. Hybridoma 14: 37-44, 1995.
7. Jeschke U, Richter DU, Walzel H, Bergemann C, Mylonas I, Sharma S, Keil C, Briese V and Friese K: Stimulation of hCG and inhibition of hPL in isolated human trophoblast cells in vitro by glycodelin A. Arch Gynecol Obstet 268: 162-167, 2003.
8. Cao Y, Schlag PM and Karsten U: Immunodetection of epithelial mucins (Muc1, Muc3) and mucin-associated glycotopes (TF, Tn and sialosyl-Tn) in benign and malignant lesions of colon epithelium: apolar localization corresponds to the malignant transformation. Virchows Arch 431: 159-166, 1997.
9. Cao Y, Karsten U, Otto G and Bannasch P: Expression of Muc1, Thomsen-Friedenreich antigen, Tn, sialosyl-Tn and α2,6linked sialic acid in hepatocellular carcinomas and preneoplastic hepatocellular lesions. Virchows Arch 434: 503-509, 1999.
10. Cao Y, Blohm D, Ghadimi M, Stosiek P, Xing PX and Karsten U: Mucins (Muc1 and Muc3) of gastrointestinal and breast epithelia reveal different and heterogeneous tumor-associated aberrations in glycosylation. J Histochem Cytochem 45: 1547-1557, 1997.
11. Hammer A, Blaschitz A, Daxböck C, Walcher W and Döhr G: Fas and Fas-Ligand are expressed in the uteroplacental unit of first-trimester pregnancy. Am J Reprod Immunol 41: 41-51, 1999.