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Volumn 20, Issue 1-4, 2007, Pages 143-156

Homologous desensitisation of the mouse leukotriene B 4 receptor involves protein kinase C-mediated phosphorylation of serine 127

Author keywords

BLT1; Desensitisation; GPCR; PKC; Xenopus laevis

Indexed keywords

ARACHIDONIC ACID DERIVATIVE; CALCIUM; CHLORIDE; COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE D4; PROSTAGLANDIN E2; PROTEIN KINASE C; SERINE;

EID: 34250743047     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000104162     Document Type: Article
Times cited : (4)

References (49)
  • 2
    • 0034618068 scopus 로고    scopus 로고
    • A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders
    • Yokomizo T, Kato K, Terawaki K, Izumi T, Shimizu T: A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. J Exp Med 2000;192:421-432.
    • (2000) J Exp Med , vol.192 , pp. 421-432
    • Yokomizo, T.1    Kato, K.2    Terawaki, K.3    Izumi, T.4    Shimizu, T.5
  • 4
    • 4544296118 scopus 로고    scopus 로고
    • T-cell trafficking in asthma: Lipid mediators grease the way
    • Luster AD, Tager AM: T-cell trafficking in asthma: lipid mediators grease the way. Nat Rev Immunol 2004;4:711-724.
    • (2004) Nat Rev Immunol , vol.4 , pp. 711-724
    • Luster, A.D.1    Tager, A.M.2
  • 5
    • 33646473075 scopus 로고    scopus 로고
    • Differential induction of BLT receptor expression on human endothelial cells by lipopolysaccharide, cytokines, and leukotriene B4
    • Qiu H, Johansson AS, Sjostrom M, Wan M, Schroder O, Palmblad J, Haeggstrom JZ: Differential induction of BLT receptor expression on human endothelial cells by lipopolysaccharide, cytokines, and leukotriene B4. Proc Natl Acad Sci U S A 2006;103:6913-6918.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6913-6918
    • Qiu, H.1    Johansson, A.S.2    Sjostrom, M.3    Wan, M.4    Schroder, O.5    Palmblad, J.6    Haeggstrom, J.Z.7
  • 6
    • 0021826463 scopus 로고
    • Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes
    • Goldman DW, Chang F-H, Gifford LA, Goetzl EJ, Bourne HR: Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes. J Exp Med 1985;162:145-156.
    • (1985) J Exp Med , vol.162 , pp. 145-156
    • Goldman, D.W.1    Chang, F.-H.2    Gifford, L.A.3    Goetzl, E.J.4    Bourne, H.R.5
  • 8
    • 0027951038 scopus 로고
    • Signal transduction mechanisms for leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils
    • Palmblad J, Lerner R, Larsson SH: Signal transduction mechanisms for leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils. J Immunol 1994;152:262-269.
    • (1994) J Immunol , vol.152 , pp. 262-269
    • Palmblad, J.1    Lerner, R.2    Larsson, S.H.3
  • 9
    • 0032042756 scopus 로고    scopus 로고
    • G protein-coupled receptor adaptation mechanisms
    • Ferguson SS, Caron MG: G protein-coupled receptor adaptation mechanisms. Semin Cell Dev Biol 1998;9:119-127.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 119-127
    • Ferguson, S.S.1    Caron, M.G.2
  • 10
    • 0030296744 scopus 로고    scopus 로고
    • G protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications
    • Chuang TT, Iacovelli L, Sallese M, De BA: G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications. Trends Pharmacol Sci 1996;17:416-421.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 416-421
    • Chuang, T.T.1    Iacovelli, L.2    Sallese, M.3    De, B.A.4
  • 11
    • 0344585389 scopus 로고    scopus 로고
    • Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6
    • Kavelaars A, Vroon A, Raatgever RP, Fong AM, Premont RT, Patel DD, Lefkowitz RJ, Heijnen CJ: Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. J Immunol 2003;171:6128-6134.
    • (2003) J Immunol , vol.171 , pp. 6128-6134
    • Kavelaars, A.1    Vroon, A.2    Raatgever, R.P.3    Fong, A.M.4    Premont, R.T.5    Patel, D.D.6    Lefkowitz, R.J.7    Heijnen, C.J.8
  • 12
    • 4944255131 scopus 로고    scopus 로고
    • Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestins
    • Chen Z, Gaudreau R, Le GC, Rola-Pleszczynski M, Stankova J: Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestins. Mol Pharmacol 2004;66:377-386.
    • (2004) Mol Pharmacol , vol.66 , pp. 377-386
    • Chen, Z.1    Gaudreau, R.2    Le, G.C.3    Rola-Pleszczynski, M.4    Stankova, J.5
  • 13
    • 0037200061 scopus 로고    scopus 로고
    • Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization
    • Gaudreau R, Le GC, Venne MH, Stankova J, Rola-Pleszczynski M: Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization. J Biol Chem 2002;277:31567-31576.
    • (2002) J Biol Chem , vol.277 , pp. 31567-31576
    • Gaudreau, R.1    Le, G.C.2    Venne, M.H.3    Stankova, J.4    Rola-Pleszczynski, M.5
  • 14
    • 14244262888 scopus 로고    scopus 로고
    • Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors
    • Jala VR, Shao WH, Haribabu B: Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors. J Biol Chem 2005;280:4880-4887.
    • (2005) J Biol Chem , vol.280 , pp. 4880-4887
    • Jala, V.R.1    Shao, W.H.2    Haribabu, B.3
  • 15
    • 0035895825 scopus 로고    scopus 로고
    • Identification of a murine cysteinyl leukotriene receptor by expression in Xenopus laevis oocytes
    • Mollerup J, Jorgensen ST, Hougaard C, Hoffmann EK: Identification of a murine cysteinyl leukotriene receptor by expression in Xenopus laevis oocytes. Biochim Biophys Acta 2001;1517:455-459.
    • (2001) Biochim Biophys Acta , vol.1517 , pp. 455-459
    • Mollerup, J.1    Jorgensen, S.T.2    Hougaard, C.3    Hoffmann, E.K.4
  • 16
    • 1642361825 scopus 로고    scopus 로고
    • Co-expression of mCysLT1 receptors and IK channels in Xenopus laevis oocytes elicits LTD4-stimulated IK current, independent of an increase in [Ca2+]i
    • Wulff T, Hougaard C, Klaerke DA, Hoffmann EK: Co-expression of mCysLT1 receptors and IK channels in Xenopus laevis oocytes elicits LTD4-stimulated IK current, independent of an increase in [Ca2+]i. Biochim Biophys Acta 2004;1660:75-79.
    • (2004) Biochim Biophys Acta , vol.1660 , pp. 75-79
    • Wulff, T.1    Hougaard, C.2    Klaerke, D.A.3    Hoffmann, E.K.4
  • 17
    • 0024333253 scopus 로고
    • Determination of ionic permeability coefficients of the plasma membrane of Xenopus laevis oocytes under voltage clamp
    • Costa PF, Emilio MG, Fernandes PL, Ferreira HG, Ferreira KG: Determination of ionic permeability coefficients of the plasma membrane of Xenopus laevis oocytes under voltage clamp. J Physiol Lond 1989;413:199-211.
    • (1989) J Physiol Lond , vol.413 , pp. 199-211
    • Costa, P.F.1    Emilio, M.G.2    Fernandes, P.L.3    Ferreira, H.G.4    Ferreira, K.G.5
  • 18
    • 0024288390 scopus 로고    scopus 로고
    • Snyder PM, Krause K-H, Welsh MJ: Inositol triphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influxin Xenopus laevis oocytes. J Biol Chem 1988;263:11048-11051.
    • Snyder PM, Krause K-H, Welsh MJ: Inositol triphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influxin Xenopus laevis oocytes. J Biol Chem 1988;263:11048-11051.
  • 19
    • 0021646375 scopus 로고
    • Chloride current induced by injection of calcium into Xenopus oocytes
    • Miledi R, Parker I: Chloride current induced by injection of calcium into Xenopus oocytes. J Physiol 1984;357:173-183.
    • (1984) J Physiol , vol.357 , pp. 173-183
    • Miledi, R.1    Parker, I.2
  • 20
    • 0022270897 scopus 로고
    • Role of calcium mobilization in mediation of acetylcholine-evoked chloride currents in Xenopus laevis oocytes
    • Dascal N, Gillo B, Lass Y: Role of calcium mobilization in mediation of acetylcholine-evoked chloride currents in Xenopus laevis oocytes. J Physiol 1985;366:299-313.
    • (1985) J Physiol , vol.366 , pp. 299-313
    • Dascal, N.1    Gillo, B.2    Lass, Y.3
  • 21
    • 0027305397 scopus 로고
    • Receptor-evoked Cl- current in Xenopus oocytes is mediated through a beta-type phospholipase C. Cloning of a new form of the enzyme
    • Ma HW, Blitzer RD, Healy EC, Premont RT, Landau EM, Iyengar R: Receptor-evoked Cl- current in Xenopus oocytes is mediated through a beta-type phospholipase C. Cloning of a new form of the enzyme. J Biol Chem 1993;268:19915-19918.
    • (1993) J Biol Chem , vol.268 , pp. 19915-19918
    • Ma, H.W.1    Blitzer, R.D.2    Healy, E.C.3    Premont, R.T.4    Landau, E.M.5    Iyengar, R.6
  • 23
    • 0033567416 scopus 로고    scopus 로고
    • cDNA cloning and characterization of guinea-pig leukotriene B4 receptor
    • Masuda K, Yokomizo T, Izumi T, Shimizu T: cDNA cloning and characterization of guinea-pig leukotriene B4 receptor. Biochem J 1999;342 ( Pt 1):79-85.
    • (1999) Biochem J , vol.342 , Issue.PART 1 , pp. 79-85
    • Masuda, K.1    Yokomizo, T.2    Izumi, T.3    Shimizu, T.4
  • 25
    • 0025226512 scopus 로고
    • Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents
    • Falcone RC, Aharony D: Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents. Pharm Exp Ther 1990;255:565-571.
    • (1990) Pharm Exp Ther , vol.255 , pp. 565-571
    • Falcone, R.C.1    Aharony, D.2
  • 26
    • 28444431957 scopus 로고    scopus 로고
    • Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
    • Back M, Bu DX, Branstrom R, Sheikine Y, Yan ZQ, Hansson GK: Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Proc Natl Acad Sci U S A 2005;102:17501-17506.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17501-17506
    • Back, M.1    Bu, D.X.2    Branstrom, R.3    Sheikine, Y.4    Yan, Z.Q.5    Hansson, G.K.6
  • 28
    • 0025347251 scopus 로고
    • Inactivation of calcium-activated chloride conductance in Xenopus oocytes: Roles of calcium and protein kinase C
    • Boton R, Singer D, Dascal N: Inactivation of calcium-activated chloride conductance in Xenopus oocytes: roles of calcium and protein kinase C. Pflugers Arch 1990;416:1-6.
    • (1990) Pflugers Arch , vol.416 , pp. 1-6
    • Boton, R.1    Singer, D.2    Dascal, N.3
  • 29
    • 0023096547 scopus 로고
    • Quantitation of protein kinase C by immunoblot-expression in different cell lines and response to phorbol esters
    • Stabel S, Rodriguez-Pena A, Young S, Rozengurt E, Parker PJ: Quantitation of protein kinase C by immunoblot-expression in different cell lines and response to phorbol esters. J Cell Physiol 1987;130:111-117.
    • (1987) J Cell Physiol , vol.130 , pp. 111-117
    • Stabel, S.1    Rodriguez-Pena, A.2    Young, S.3    Rozengurt, E.4    Parker, P.J.5
  • 30
    • 25444468323 scopus 로고    scopus 로고
    • Leukotriene B4 receptor and the function of its helix 8
    • Okuno T, Yokomizo T, Hori T, Miyano M, Shimizu T: Leukotriene B4 receptor and the function of its helix 8. J Biol Chem 2005;280:32049-32052.
    • (2005) J Biol Chem , vol.280 , pp. 32049-32052
    • Okuno, T.1    Yokomizo, T.2    Hori, T.3    Miyano, M.4    Shimizu, T.5
  • 31
    • 0029745744 scopus 로고    scopus 로고
    • Activation of different Cl currents in Xenopus oocytes by Ca liberated from stores and by capacitative Ca influx
    • Hartzell HC: Activation of different Cl currents in Xenopus oocytes by Ca liberated from stores and by capacitative Ca influx. J Gen Physiol 1996;108:157-175.
    • (1996) J Gen Physiol , vol.108 , pp. 157-175
    • Hartzell, H.C.1
  • 32
    • 0024496741 scopus 로고
    • Two calcium-activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187
    • Boton R, Dascal N, Gillo B, Lass Y: Two calcium-activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187. J Physiol Lond 1989;408:511-534.
    • (1989) J Physiol Lond , vol.408 , pp. 511-534
    • Boton, R.1    Dascal, N.2    Gillo, B.3    Lass, Y.4
  • 33
    • 0032894279 scopus 로고    scopus 로고
    • Dynamics of calcium regulation of chloride currents in Xenopus oocytes
    • Kuruma A, Hartzell HC: Dynamics of calcium regulation of chloride currents in Xenopus oocytes. Am J Physiol 1999;276:C161-C175.
    • (1999) Am J Physiol , vol.276
    • Kuruma, A.1    Hartzell, H.C.2
  • 34
    • 0029962929 scopus 로고    scopus 로고
    • Characterization of the pharmacological profile of the potent LTB4 antagonist CP-105,696 on murine LTB4 receptors in vitro
    • Showell HJ, Breslow R, Conklyn MJ, Hingorani GP, Koch K: Characterization of the pharmacological profile of the potent LTB4 antagonist CP-105,696 on murine LTB4 receptors in vitro. Br J Pharmacol 1996;117:1127-1132.
    • (1996) Br J Pharmacol , vol.117 , pp. 1127-1132
    • Showell, H.J.1    Breslow, R.2    Conklyn, M.J.3    Hingorani, G.P.4    Koch, K.5
  • 35
    • 0026581534 scopus 로고
    • A rapid microtiter plate method for the detection of lysozyme release from human neutrophils
    • Moreira-Ludewig R, Healy CT: A rapid microtiter plate method for the detection of lysozyme release from human neutrophils. J Pharmacol Toxicol Methods 1992;27:95-100.
    • (1992) J Pharmacol Toxicol Methods , vol.27 , pp. 95-100
    • Moreira-Ludewig, R.1    Healy, C.T.2
  • 37
    • 0024811613 scopus 로고
    • Influence of standard and novel LTB4 analogs on human neutrophil chemotaxis measured by the multiwell cap assay
    • Psychoyos S, Uziel FS, Bhagwat S, Morrissey MM: Influence of standard and novel LTB4 analogs on human neutrophil chemotaxis measured by the multiwell cap assay. J Immunol Methods 1989;124:189-196.
    • (1989) J Immunol Methods , vol.124 , pp. 189-196
    • Psychoyos, S.1    Uziel, F.S.2    Bhagwat, S.3    Morrissey, M.M.4
  • 38
    • 0024473556 scopus 로고
    • Comparison of LTB4- and C5a-stimulated chemotaxis of isolated human neutrophils: Difference revealed by cell migration in thick filters using the multiwell cap procedure
    • Psychoyos S, Uziel FS: Comparison of LTB4- and C5a-stimulated chemotaxis of isolated human neutrophils: difference revealed by cell migration in thick filters using the multiwell cap procedure. Agents Actions 1989;27:380-384.
    • (1989) Agents Actions , vol.27 , pp. 380-384
    • Psychoyos, S.1    Uziel, F.S.2
  • 40
    • 0023820441 scopus 로고
    • Leukotriene B4-induced homologous desensitization of calcium mobilization and phosphoinositide metabolism in U-937 cells
    • Winkler JD, Sarau HM, Foley JJ, Mong S, Crooke ST: Leukotriene B4-induced homologous desensitization of calcium mobilization and phosphoinositide metabolism in U-937 cells. J Pharmacol Exp Ther 1988;246:204-210.
    • (1988) J Pharmacol Exp Ther , vol.246 , pp. 204-210
    • Winkler, J.D.1    Sarau, H.M.2    Foley, J.J.3    Mong, S.4    Crooke, S.T.5
  • 41
    • 0021893473 scopus 로고
    • Transduction by leukotriene B4 receptors of increases in cytosolic calcium in human polymorphonuclear leukocytes
    • Goldman DW, Gifford LA, Olson DM, Goetzl EJ: Transduction by leukotriene B4 receptors of increases in cytosolic calcium in human polymorphonuclear leukocytes. J Immunol 1985;135:525-530.
    • (1985) J Immunol , vol.135 , pp. 525-530
    • Goldman, D.W.1    Gifford, L.A.2    Olson, D.M.3    Goetzl, E.J.4
  • 42
    • 0025197287 scopus 로고
    • Effect of leukotriene B4 on enhancement of superoxide production evoked by formyl-methionyl-leucylphenylalanine in myeloid differentiated HL-60 cells: Possible involvement of intracellular calcium influx and high affinity receptor for leukotriene B4
    • Harada Y: Effect of leukotriene B4 on enhancement of superoxide production evoked by formyl-methionyl-leucylphenylalanine in myeloid differentiated HL-60 cells: possible involvement of intracellular calcium influx and high affinity receptor for leukotriene B4. Hiroshima J Med Sci 1990;39:89-94.
    • (1990) Hiroshima J Med Sci , vol.39 , pp. 89-94
    • Harada, Y.1
  • 43
    • 0022602258 scopus 로고
    • Development of receptors for leukotriene B4 on HL-60 cells induced to differentiate by 1 alpha,25-dihydroxyvitamin D3
    • Goldman DW, Olson DM, Payan DG, Gifford LA, Goetzl EJ: Development of receptors for leukotriene B4 on HL-60 cells induced to differentiate by 1 alpha,25-dihydroxyvitamin D3. J Immunol 1986;136:4631-4636.
    • (1986) J Immunol , vol.136 , pp. 4631-4636
    • Goldman, D.W.1    Olson, D.M.2    Payan, D.G.3    Gifford, L.A.4    Goetzl, E.J.5
  • 44
    • 0028126950 scopus 로고
    • Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes
    • Quick MW, Simon MI, Davidson N, Lester HA, Aragay AM: Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes. J Biol Chem 1994;269:30164-30172.
    • (1994) J Biol Chem , vol.269 , pp. 30164-30172
    • Quick, M.W.1    Simon, M.I.2    Davidson, N.3    Lester, H.A.4    Aragay, A.M.5
  • 46
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell LM, Lefkowitz RJ: The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci 2002;115:455-465.
    • (2002) J Cell Sci , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 47
    • 0027368179 scopus 로고
    • Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization
    • Ali H, Richardson RM, Tomhave ED, Didsbury JR, Snyderman R: Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization. J Biol Chem 1993;268:24247-24254.
    • (1993) J Biol Chem , vol.268 , pp. 24247-24254
    • Ali, H.1    Richardson, R.M.2    Tomhave, E.D.3    Didsbury, J.R.4    Snyderman, R.5
  • 49
    • 27844543454 scopus 로고    scopus 로고
    • The G protein-coupled receptors: Pharmacogenetics and disease
    • Thompson MD, Burnham WM, Cole DE: The G protein-coupled receptors: pharmacogenetics and disease. Crit Rev Clin Lab Sci 2005;42:311-392.
    • (2005) Crit Rev Clin Lab Sci , vol.42 , pp. 311-392
    • Thompson, M.D.1    Burnham, W.M.2    Cole, D.E.3


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