T-cadherin enhances cell-matrix adhesiveness by regulating β1 integrin trafficking in cutaneous squamous carcinoma cells

Genes to Cells

Volumn 12, Issue 6, 2007, Pages 787-796

  Mukoyama, Yohei ^a,b   Utani, Atsushi ^a   Matsui, Seiya ^a,b   Zhou, Shuxia ^c   Miyachi, Yoshiki ^a   Matsuyoshi, Norihisa ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Maruho Co   (Japan)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CADHERIN; CHOLERA TOXIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; T CADHERIN; TETRACYCLINE; UNCLASSIFIED DRUG;

ARTICLE; CAVEOLA; CELL ADHESION; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTERNALIZATION; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

ANTIGENS, CD29; CADHERINS; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL LINE; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; KERATINOCYTES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SKIN NEOPLASMS;

CYTOMEGALOVIRUS;

EID: 34250741377     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2007.01092.x     Document Type: Article

References (34)

1. Anderson, R.G. (1998) The caveolae membrane system. Annu. Rev. Biochem. 67, 199-225.
2. Bill, H.M., Knudsen, B., Moores, S.L., Muthuswamy, S.K., Rao, V.R., Brugge, J.S. & Miranti, C.K. (2004) Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells. Mol. Cell. Biol. 24, 8586-8599.
3. Biscardi, J.S., Maa, M.C., Tice, D.A., Cox, M.E., Leu, T.H. & Parsons, S.J. (1999) c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J. Biol. Chem. 274, 8335-8343.
4. Brown, D.A. & London, E. (2000) Structure and function of sphingolipid and cholesterol-rich membrane rafts. J. Biol. Chem. 275, 17221-17224.
5. Carter, W.G., Wayner, E.A., Bouchard, T.S. & Kaur, P. (1990) The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epidermal cells. J. Cell Biol. 110, 1387-1404.
6. Kasahara, K. & Sanai, Y. (2000) Functional roles of glycosphingolipids in signal transduction via lipid rafts. Glycoconj. J. 17, 153-162.
7. Kondo, S. & Aso, K. (1981) Establishment of a cell line of human skin squamous cell carcinoma in vitro. Br. J. Dermatol. 105, 125-132.
8. Lu, Z., Ghosh, S., Wang, Z. & Hunter, T. (2003) Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion. Cancer Cell 4, 499-515.
9. Marjomaki, V., Pietiainen, V., Matilainen, H., Upla, P., Ivaska, J., Nissinen, L., Reunanen, H., Huttunen, P., Hyypia, T. & Heino, J. (2002) Internalization of echovirus 1 in caveolae. J. Virol. 76, 1856-1865.
10. Maxfield, F.R. (2002) Plasma membrane microdomains. Curr. Opin. Cell Biol. 14, 483-487.
11. Mineo, C., Gill, G.N. & Anderson, R.G. (1999) Regulated migration of epidermal growth factor receptor from caveolae. J. Biol. Chem. 274, 30636-30643.
12. Montesano, R., Roth, J., Robert, A. & Orci, L. (1982) Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature 296, 651-653.
13. Mukoyama, Y., Zhou, S., Miyachi, Y. & Matsuyoshi, N. (2005) T-cadherin negatively regulates the proliferation of cutaneous squamous carcinoma cells. J. Invest. Dermatol. 124, 833-838.
14. Nabi, I.R. & Le, P.U. (2003) Caveolae/raft-dependent endocytosis. J. Cell Biol. 161, 673-677.
15. Nagafuchi, A. & Takeichi, M. (1988) Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7, 3679-3684.
16. Parton, R.G., Joggerst, B. & Simons, K. (1994) Regulated internalization of caveolae. J. Cell Biol. 127, 1199-1215.
17. Peltonen, J., Larjava, H., Jaakkola, S., Gralnick, H., Akiyama, S. K., Yamada, S. S., Yamada, K. M. & Uitto, J. (1989) Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas. J. Clin. Invest. 84, 1916-1923.
18. Philippova, M.P., Bochkov, V.N., Stambolsky, D.V., Tkachuk, V.A. & Resink, T.J. (1998) T-cadherin and signal-transducing molecules co-localize in caveolin-rich membrane domains of vascular smooth muscle cells. FEBS Lett. 429, 207-210.
19. Ranscht, B. & Dours-Zimmermann, M.T. (1991) T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region. Neuron 7, 391-402.
20. Sharma, D.K., Brown, J.C., Cheng, Z., Holicky, E.L., Marks, D.L. & Pagano, R.E. (2005) The glycosphingolipid, lactosylceramide, regulates β1-integrin clustering and endocytosis. Cancer Res. 65, 8233-8241.
21. Shimoyama, Y., Hirohashi, S., Hirano, S., Noguchi, M., Shimosato, Y., Takeichi, M. & Abe, O. (1989) Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res. 49 2128-2133.
22. Shirk, A.J. & Kuver, R. (2005) Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cells. BMC Gastroenterol. 5, 12.
23. Shogomori, H. & Futerman, A. H. (2001) Cholera toxin is found in detergent-insoluble rafts/domains at the cell surface of hippocampal neurons but is internalized via a raft-independent mechanism. J. Biol. Chem. 276, 9182-9188.
24. Simons, K. & Toomre, D. (2000) Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1, 31-39.
25. Smart, E.J., Ying, Y.S., Mineo, C. & Anderson, R.G. (1995) A detergent-free method for purifying caveolae membrane from tissue culture cells. Proc. Natl. Acad. Sci. USA 92, 10104-10108.
26. Stappert, J. & Kemler, R. (1994) A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Adhes. Commun. 2, 319-327.
27. Takeuchi, T., Liang, S.B., Matsuyoshi, N., Zhou, S., Miyachi, Y., Sonobe, H. & Ohtsuki, Y. (2002) Loss of T-cadherin (CDH13, H-cadherin) expression in cutaneous squamous cell carcinoma. Lab. Invest. 82, 1023-1029.
28. Torgersen, M.L., Skretting, G., van Deurs, B. & Sandvig, K. (2001) Internalization of cholera toxin by different endocytic mechanisms. J. Cell Sci. 114, 3737-3747.
29. Upla, P., Marjomaki, P.V., Kankaanpaa, P., Ivaska, J., Hyypia, T., Van Der Goot, F.G. & Heino, J. (2004) Clustering induces a lateral redistribution of α2β1 integrin from membrane rafts to caveolae and subsequent protein kinase C-dependent internalization. Mol. Biol. Cell 15, 625-636.
30. Utani, A., Nomizu, M., Matsuura, H., Kato, K., Kobayashi, T., Takeda, U., Aota, S., Nielsen, P.K. & Shinkai, H. (2001) A unique sequence of the laminin α3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4. J. Biol. Chem. 276, 28779-28788.
31. Watt, F.M. (2002) Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J. 21, 3919-3926.
32. Wolf, A.A., Jobling, M.G., Wimer-Mackin, S., Ferguson-Maltzman, M., Madara, J.L., Holmes, R.K. & Lencer, W.I. (1998) Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia. J. Cell Biol. 141, 917-927.
33. Yap, A.S., Niessen, C.M. & Gumbiner, B.M. (1998) The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J. Cell Biol. 141, 779-789.
34. Zhou, S., Matsuyoshi, N., Liang, S. B., Takeuchi, T., Ohtsuki, Y. & Miyachi, Y. (2002) Expression of T-cadherin in basal keratinocytes of skin. J. Invest. Dermatol. 118, 1080-1084.