Hypocholesterolemic effect of protein isolated from quinoa (Chenopodium quinoa willd.) seeds

Food Science and Technology Research

Volumn 11, Issue 2, 2005, Pages 161-167

  Takao, Tetsuya ^a   Watanabe, Nakamichi ^a   Yuhara, Kana ^a   Itoh, Syoko ^a   Suda, Saori ^a   Tsuruoka, Yukari ^a   Nakatsugawa, Kenichi ^a   Konishi, Yotaro ^b  

^a SHOWA WOMEN'S UNIVERSITY   (Japan)

^b Osaka City University   (Japan)

Author keywords

Cholesterol; Hypocholesterolemic effect; Protein; Quinoa

Indexed keywords

CHENOPODIUM QUINOA;

EID: 34250687274     PISSN: 13446606     EISSN: None     Source Type: Journal    
DOI: 10.3136/fstr.11.161     Document Type: Article

References (38)

1. Anderson, J.W., Deakins, D.A. and Bridges, R.S. (1990). "Dietary Fiber" Plenum Press, New York, 339-363.
2. Anderson, J.W., Jones, A.E. and Riddel-Mason, S. (1994). Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol-fed rats. J. Nutr, 124, 78-83.
3. Aluko, R.E. and Monu, E. (2003). Functional and bioactive properties of quinoa seed protein hydrolysates. J. Food Sci., 68, 1254-1258.
4. Armando, R.T., Frenanda, M., Cristino, C., Rogelio, HP., Carlos, A. A., Jose, P.C., Ricardo, C.R. and Nimbe, T. (2002). A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipid and renal fibrogenic cytokines in rats with chronic nephrotic syndrome. J Nutr., 132, 2562-2569.
5. Bell, S., Goldman, V.M., Bistrian, B.R., Arnold, A.H., Ostroff, G.O. and Forse, R.A., (1999). Effect of beta-glucan from oats and yeast on serum lipids. Clit. Rev. Food Sci. Nutr., 39, 189-202.
6. Chaturvedi, A., Sarojinim G. and Devi, N.L. (1993). Hypocholesterolemic effect of amaranth seeds (Amaranthus esculantus). Plant Foods Hum Nutr. 44, 63-70.
7. Chauhan, G.S., Eskin, N.A.M. and Mills, P.A. (1999). Effect of saponin extraction on the nutritional quality of quinoa (Chenopodium quinoa Willd.) proteins. J Food Sci. Technol., 2, 123-126.
8. Chomczynski, P. and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
9. Coulter, L. and Lorenz, K. (1990). Quinoa: Composition, Nutritional value, food applications. Lebensm.-Wiss, u.-Technol. 23, 203-207.
10. Fleming, J.E. and Galwey, I. (1995). "Cereals and pseudocereals," Chapman ad Hall, London, 3-83.
11. Eneroth, P., Hellstrom, K. and Sjovall, J. (1968). Method for quantitative determination of bile acids in human feces. Bile acids and steroids 195. Acta Chem Scand., 22, 1729-1744.
12. Gee, J.M., Price, K.R., Ridout, C.L., Wortley, G.M., Hurrell, R.F. and Johnson, I.T. (1993). Saponins of Quinoa (Chenopodium quinoa): Effect of processing on ther abundance in quinoa products and their biological effects on intestinal mucosal tissue. J Sci. Food Agric., 63, 201-209.
13. Hwa, J.J., Zollman, S., Warden, C.H., Taylor, B.A., Edwards, P.A., Fogelman, A.M.and Lusis, A.J. (1992). Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res., 33, 711-725.
14. Huff, M.W., Hamilton, R.M.G. and Carrol, K.K. (1977). Plasma cholesterol levels in rabbits fed low fat, cholesterol-free, semi-purified diets: effects of dietary proteins, protein hydrolysates and amino acid mixtures. Atherosclerosis, 28, 187-195.
15. Kayashita, J., Shimaoka, I. and Nakajyoh, M. (1995). Hypocholestrolemic effect of buckwheat protein extract in rats fed cholesterol enriched diets. Nutr. Res., 15, 691-698.
16. Kayashita, J., Shimaoka, I., Nakajoh, M., Yamazaki, M. and Kato, N. (1997). Consumption of buckwheat protein lowers serum cholesterol and raises fecal neutral sterols in cholesterol-fed rats because of its lower digestibility. J. Nutr., 127, 1395-1400.
17. Konishi, Y., Arai, N., Umeda, J., Gunji, N., Saeki, S., Takao, T., Minoguchi, R. and Kensho, G. (2000). Cholesterol lowering effect of the methanol insoluble materials from the quinoa seed pericarp. In "Hydrocolloids Part 2," ed. by Nishinari, K., Elsevier Science, B.V., 417-422.
18. Koziol, M. J. (1992). Chemical composition and nutritional evaluation of quinoa (Chenopodiumu quinoa Willd.). J. Food Comp. Anal., 5, 35-68.
19. Nagaoka, S., Miwa, K., Eto, M., Kuzuya, Y. and Hori, G. (1999). Soy protein peptic hydrolysate with bound phospholipids decreases micellar solubility and cholesterol absorption in rats and Caco-2 cells. J. Nutr., 129, 1725-1730.
20. Nagata, Y. and Tanaka, K. (1981). Sugano, M., Serum and liver cholesterol levels of rats and mice fed soy-bean protein or casein. J. Nutr. Sci. Vitaminol., 27, 586-593.
21. Matsuo, M. (2000). Plasma cholesterol reduction by defatted soy ontjom (fermented with Neurospora intermedia) in rats fed a cholesterol-free diet. J Nutr Sci. Vitamino., 46, 30-33.
22. Nishizawa, N. and Fudamoto, Y. (1995). The elevation of plasma concentration of high-density lipoprotein cholesterol in mice fed with protein from proso millet. Biosci Biotechnol Biochem., 59, 333-335.
23. Nishizawa, N., Shimanuki, S., Fujihashi, H., Watanabe, H., Fudamoto, Y. and Nagasawa, T. (1996). Proso millet protein elevates plasma level of high-density lipoprotein: a new food function of proso millet. Biomed Environ Sci., 9, 209-212.
24. Ogawa, H., Watanabe, K., Mitsunaga, T. and Meguro, T. (2001). Effect of quinoa on blood pressure and lipid metabolism in diet-induced hyperlipidemic spontaneously hypertensive rats (SHR). J. Jpn. Soc. Nutr, Food Sci., 54, 221-227.
25. Ranhotra, G.R., Gelroth, J.A., Glaser, B.K., Lorenz, K.J. and Johnson, D.L. (1993). Composition and protein nutritional quality of quinoa. Cereal Chem., 70, 303-305.
26. Rodriguez, V.M., Portillo, M.P., Pico, C., Macarulla, M.T. and Palou, A. (2002). Olive oil feeding up-regulates uncoupling protein genes in rat brown adipose tissue and skeletal muscle. Am. J. Clin. Nutr., 75, 213-220.
27. Ruales, J. and Nair, B. (1992). Nutritional quality of protein in quinoa (Chenopodium quinoa, Willd) seeds. Plant Foods Human Nutr., 42, 1-11.
28. Ruales, J. and Nair, B.M. (1993). Content of fat, vitamins and minerals in quinoa (Chenopodium quinoa, Willd) seeds. Food Chem., 48, 131-136.
29. Segura-Nieto, M., Shewry, R.P. and Paredes-Lopez, O. (1999). Globulins of the pseudocereals: Amaranth, Quinoa, and Buckwheat. Seed proteins, ed. by Shewry. R.P. and Casey R., Kluwer Acdemic Publishers, 453-475.
30. Rudling, M. (1992). Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo. J Lipid Res., 33, 493-501.
31. Shin, D.H., Heo, H.J., Lee, Y.J. and Kim, H.K. (2004). Amaranth squalene reduces serum and liver lipid levels in rats fed a cholesterol diet. Br J Biomed Sci., 61, 11-14.
32. Sugano, M. (1987) Nutiritional studies on the regulation of cholesterol metabolism. J. Jpn. Soc. Nutr. Food Sci., 40, 93-102.
33. Sugano, M., Goto, S., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T. and Kimoto, M. (1990). Cholesterol-lowering activity of various undigested fraction of soy bean protein in rats. J. Nutr., 20, 977-985.
34. Terpstra, A.H., van Tintelen, G. and West, C.E. (1982). The hypo-cholesterolemic effect of dietary soy protein in rats. J. Nutr., 112, 810-817.
35. Truswell, A.S. (1995). Dietary fibre and blood lipids. Curr. Opin. Lipidol., 6, 14-19.
36. Weber, J.E. (1978). The Inca's ancient answer to food storage, Nature, 272, 48.
37. Woldemichael, G.M. and Wink, M. (2001). Identification and biological activities of triterpenoid saponins from Chenopodium quinoa. J Agric. Food Chem. 49, 2327-2332.
38. Yamaguchi, Y., Kitagawa, S., Imaizumi, N., Kunitomo, M. and Fujiwara, M. (1993). Enhancement of aortic cholesterol deposition by dietary linoleic acid in cholesterol-fed mice: An animal model for primary screening of antiatheroslerotic agents. J. pharmacol toxicol method, 30, 169-175.