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Volumn 42, Issue 3, 2007, Pages 447-454

Ocular drug delivery: Molecules, cells, and genes

Author keywords

Cells; Gene therapy; Molecules; Ocular diseases

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; DNA; POLYPEPTIDE; VIRUS VECTOR;

EID: 34250685723     PISSN: 00084182     EISSN: 17153360     Source Type: Journal    
DOI: 10.3129/I07-049     Document Type: Conference Paper
Times cited : (17)

References (56)
  • 2
    • 33646925637 scopus 로고    scopus 로고
    • Fluocinlone Acetonide Uveitis Study Group. Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: Thirty-four-week results of a multicenter randomized clinical study
    • Jaffe GJ, Martin D, Callanan D, Pearson PA, Levy B, Comstock T. Fluocinlone Acetonide Uveitis Study Group. Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study. Ophthalmology 2006;113:1020-7.
    • (2006) Ophthalmology , vol.113 , pp. 1020-1027
    • Jaffe, G.J.1    Martin, D.2    Callanan, D.3    Pearson, P.A.4    Levy, B.5    Comstock, T.6
  • 3
    • 0142139213 scopus 로고    scopus 로고
    • Scleral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis
    • Sakurai E, Nozaki M, Okabe K, Kunou N, Kimura H, Ogura Y. Scleral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis. Invest Ophthalmol Vis Sci 2003;44:4845-52.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4845-4852
    • Sakurai, E.1    Nozaki, M.2    Okabe, K.3    Kunou, N.4    Kimura, H.5    Ogura, Y.6
  • 4
    • 33745655043 scopus 로고    scopus 로고
    • A novel bioerodible deep scleral lamellar cyclosporine implant for uveitis
    • Gilger BC, Salmon JH, Wilkie DA, et al. A novel bioerodible deep scleral lamellar cyclosporine implant for uveitis. Invest Ophthalmol Vis Sci 2006;47:2596-605.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2596-2605
    • Gilger, B.C.1    Salmon, J.H.2    Wilkie, D.A.3
  • 5
    • 24944512662 scopus 로고    scopus 로고
    • In vitro sustained human transscleral drug delivery of fluorescein-labeled dexamethasone and methotrexate with fibrin sealant
    • Cruysberg LP, Nuijts RM, Gilbert JA, Geroski DH, Hendrikse F, Edelhauser HF. In vitro sustained human transscleral drug delivery of fluorescein-labeled dexamethasone and methotrexate with fibrin sealant. Curr Eye Res 2005;30:653-60.
    • (2005) Curr Eye Res , vol.30 , pp. 653-660
    • Cruysberg, L.P.1    Nuijts, R.M.2    Gilbert, J.A.3    Geroski, D.H.4    Hendrikse, F.5    Edelhauser, H.F.6
  • 6
    • 33750861299 scopus 로고    scopus 로고
    • Retinal repair by transplantation of photoreceptor precursors
    • MacLaren RE, Pearson RA, MacNeil A, et al. Retinal repair by transplantation of photoreceptor precursors. Nature 2006; 444:203-7.
    • (2006) Nature , vol.444 , pp. 203-207
    • MacLaren, R.E.1    Pearson, R.A.2    MacNeil, A.3
  • 7
    • 33644872951 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants
    • Sieving PA, Caruso RC, Tao W, et al. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc Natl Acad Sci U S A 2006;103:3896-901.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 3896-3901
    • Sieving, P.A.1    Caruso, R.C.2    Tao, W.3
  • 8
    • 0032432210 scopus 로고    scopus 로고
    • Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina
    • Takahashi M, Palmer TD, Takahashi J, Gage FH. Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina. Mol Cell Neurosci 1998;12: 340-8.
    • (1998) Mol Cell Neurosci , vol.12 , pp. 340-348
    • Takahashi, M.1    Palmer, T.D.2    Takahashi, J.3    Gage, F.H.4
  • 9
    • 33745707125 scopus 로고    scopus 로고
    • Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells
    • Banin E, Obolensky A, Idelson M, et al. Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells. Stem Cells 2006;24:246-57.
    • (2006) Stem Cells , vol.24 , pp. 246-257
    • Banin, E.1    Obolensky, A.2    Idelson, M.3
  • 10
    • 33646559497 scopus 로고    scopus 로고
    • Intraocular injection of folate antagonist methotrexate induces neuronal differentiation of embryonic stem cells transplanted in the adult mouse retina
    • Hara A, Niwa M, Kumada M, et al. Intraocular injection of folate antagonist methotrexate induces neuronal differentiation of embryonic stem cells transplanted in the adult mouse retina. Brain Res 2006;1085:33-42.
    • (2006) Brain Res , vol.1085 , pp. 33-42
    • Hara, A.1    Niwa, M.2    Kumada, M.3
  • 11
    • 0344851505 scopus 로고    scopus 로고
    • Enhanced induction of RPE lineage markers in pluripotent neural stem cells engrafted into the adult rat sub-retinal space
    • Enzmann V, Howard RM, Yamauchi Y, Whittemore SR, Kaplan HJ. Enhanced induction of RPE lineage markers in pluripotent neural stem cells engrafted into the adult rat sub-retinal space. Invest Ophthalmol Vis Sci 2003;44:5417-22.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 5417-5422
    • Enzmann, V.1    Howard, R.M.2    Yamauchi, Y.3    Whittemore, S.R.4    Kaplan, H.J.5
  • 12
    • 33746059820 scopus 로고    scopus 로고
    • Application of encapsulated cell technology for retinal degenerative diseases
    • Tao W. Application of encapsulated cell technology for retinal degenerative diseases. Expert Opin Biol Ther 2006;6:717-26.
    • (2006) Expert Opin Biol Ther , vol.6 , pp. 717-726
    • Tao, W.1
  • 13
    • 11044239127 scopus 로고    scopus 로고
    • Retinal stem cells and regeneration
    • Moshiri A, Close J, Reh TA. Retinal stem cells and regeneration. Int J Dev Biol 2004;48:1003-14.
    • (2004) Int J Dev Biol , vol.48 , pp. 1003-1014
    • Moshiri, A.1    Close, J.2    Reh, T.A.3
  • 14
    • 10944237890 scopus 로고    scopus 로고
    • Neural regeneration in the chick retina
    • Fischer AJ. Neural regeneration in the chick retina. Prog Retina Eye Res 2005;24:161-82.
    • (2005) Prog Retina Eye Res , vol.24 , pp. 161-182
    • Fischer, A.J.1
  • 15
    • 0028132916 scopus 로고
    • Retinoic acid promotes differentiation of photoreceptors in vitro
    • Kelley MV, Turner JK, Reh TA. Retinoic acid promotes differentiation of photoreceptors in vitro. Development 1994; 120:2091-102.
    • (1994) Development , vol.120 , pp. 2091-2102
    • Kelley, M.V.1    Turner, J.K.2    Reh, T.A.3
  • 16
    • 0019289952 scopus 로고
    • Cellular metaplasia or transdifferentiation as a model for retinal cell differentiation
    • Okada TS. Cellular metaplasia or transdifferentiation as a model for retinal cell differentiation. Curr Top Dev Biol 1980;16:349-80.
    • (1980) Curr Top Dev Biol , vol.16 , pp. 349-380
    • Okada, T.S.1
  • 17
    • 27644496187 scopus 로고    scopus 로고
    • Delivery of neurotrophic factors and therapeutic proteins for retinal diseases
    • Thanos C, Emerich D. Delivery of neurotrophic factors and therapeutic proteins for retinal diseases. Expert Opin Bio Ther 2005;5:1443-52.
    • (2005) Expert Opin Bio Ther , vol.5 , pp. 1443-1452
    • Thanos, C.1    Emerich, D.2
  • 18
    • 33644975974 scopus 로고    scopus 로고
    • D-TAT transporter as an ocular peptide delivery system
    • Schorderet DF, Manzi V, Canola K, et al. D-TAT transporter as an ocular peptide delivery system. Clin Exp Ophthalmol 2005;3:628-35.
    • (2005) Clin Exp Ophthalmol , vol.3 , pp. 628-635
    • Schorderet, D.F.1    Manzi, V.2    Canola, K.3
  • 19
    • 32644432029 scopus 로고    scopus 로고
    • Clinical relevance of the neurotrophins and their receptors
    • Allen SJ, Dawbarn D. Clinical relevance of the neurotrophins and their receptors. Clin Sci (Lond) 2006;110:175-91.
    • (2006) Clin Sci (Lond) , vol.110 , pp. 175-191
    • Allen, S.J.1    Dawbarn, D.2
  • 20
    • 0035075348 scopus 로고    scopus 로고
    • BDNF enhances retinal ganglion cell survival in cats with optic nerve damage
    • Chen H, Weber AJ. BDNF enhances retinal ganglion cell survival in cats with optic nerve damage. Invest Ophthalmol Vis Sci 2001;42:966-74.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 966-974
    • Chen, H.1    Weber, A.J.2
  • 21
    • 26244460046 scopus 로고    scopus 로고
    • Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
    • Delyfer MN, Simonutti M, Neveux N, Leveillard T, Sahel JA. Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? Mol Vis 2005;11:677-87.
    • (2005) Mol Vis , vol.11 , pp. 677-687
    • Delyfer, M.N.1    Simonutti, M.2    Neveux, N.3    Leveillard, T.4    Sahel, J.A.5
  • 22
    • 0027504633 scopus 로고
    • Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts
    • Jiang LQ, Jorquera M, Streilein JW. Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. Invest Ophthalmol Vis Sci 1993;34:3347-54.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 3347-3354
    • Jiang, L.Q.1    Jorquera, M.2    Streilein, J.W.3
  • 23
    • 0141430092 scopus 로고    scopus 로고
    • Gene therapy with brain-derived neurotrophic factor as a protection: Retinal ganglion cells in a rat glaucoma model
    • Martin KR, Quigley HA, Zack DJ, et al. Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci 2003;44:4357-65.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4357-4365
    • Martin, K.R.1    Quigley, H.A.2    Zack, D.J.3
  • 24
    • 16244388563 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo
    • Pernet V, Hauswirth WW, Di Polo A. Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo. J Neurochem 2005;93:72-83.
    • (2005) J Neurochem , vol.93 , pp. 72-83
    • Pernet, V.1    Hauswirth, W.W.2    Di Polo, A.3
  • 25
    • 23844451245 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma
    • Zhou Y, Pernet V, Hauswirth WW, Di Polo A. Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma. Mol Ther 2005;12:402-12.
    • (2005) Mol Ther , vol.12 , pp. 402-412
    • Zhou, Y.1    Pernet, V.2    Hauswirth, W.W.3    Di Polo, A.4
  • 26
    • 2442654323 scopus 로고    scopus 로고
    • Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration
    • Bhutto IA, Kim SY, McLeod DS, et al. Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci 2004;45:1544-52.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1544-1552
    • Bhutto, I.A.1    Kim, S.Y.2    McLeod, D.S.3
  • 27
    • 0035404544 scopus 로고    scopus 로고
    • Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin
    • Mori K, Ando A, Gehlbach P, et al. Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin. Am J Pathol 2001;159:313-20.
    • (2001) Am J Pathol , vol.159 , pp. 313-320
    • Mori, K.1    Ando, A.2    Gehlbach, P.3
  • 28
    • 0038661164 scopus 로고    scopus 로고
    • Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment
    • Takahashi K, Saishin Y, Saishin Y, et al. Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment. FASEB J 2003;17:896-98.
    • (2003) FASEB J , vol.17 , pp. 896-898
    • Takahashi, K.1    Saishin, Y.2    Saishin, Y.3
  • 29
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
    • Kendall R.L., Wang G., Thomas K.A. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 1996;226:324-28.
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 30
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall R.L., Thomas K.A. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci U S A 1993;90:10705-9.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 31
    • 85047699046 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1
    • Bainbridge JW, Mistry A, De Alwis M, et al. Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther 2002;9:320-6.
    • (2002) Gene Ther , vol.9 , pp. 320-326
    • Bainbridge, J.W.1    Mistry, A.2    De Alwis, M.3
  • 32
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan RC. The basic science of gene therapy. Science 1993; 260:926-32.
    • (1993) Science , vol.260 , pp. 926-932
    • Mulligan, R.C.1
  • 34
    • 0035459495 scopus 로고    scopus 로고
    • Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo
    • Borras T, Gabelt BT, Klintworth GK, Peterson JC, Kaufman PL. Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo. J Gene Med 2001;3:437-49.
    • (2001) J Gene Med , vol.3 , pp. 437-449
    • Borras, T.1    Gabelt, B.T.2    Klintworth, G.K.3    Peterson, J.C.4    Kaufman, P.L.5
  • 35
    • 4344674793 scopus 로고    scopus 로고
    • Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo
    • Loewen N, Fautsch MP, Teo WL, Bahler CK, Johnson DH, Poeschla EM. Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo. Invest Ophthalmol Vis Sci 2004;45:3091-8.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3091-3098
    • Loewen, N.1    Fautsch, M.P.2    Teo, W.L.3    Bahler, C.K.4    Johnson, D.H.5    Poeschla, E.M.6
  • 36
    • 34250640834 scopus 로고    scopus 로고
    • Gene therapy for glaucoma: Anterior and posterior segment targets, delivery systems, constraints
    • Gramer E, Grehn F, eds, Berlin: Springer-Verlag;
    • Liu X, Brandt CR, Gabelt BT, Kaufman PL. Gene therapy for glaucoma: anterior and posterior segment targets, delivery systems, constraints. In: Gramer E, Grehn F, eds. Pathogenesis and Risk Factors of Glaucoma. Berlin: Springer-Verlag; 1999:93-100.
    • (1999) Pathogenesis and Risk Factors of Glaucoma , pp. 93-100
    • Liu, X.1    Brandt, C.R.2    Gabelt, B.T.3    Kaufman, P.L.4
  • 39
    • 0030161789 scopus 로고    scopus 로고
    • The ups and downs of adenovirus vectors
    • Ginsberg HS. The ups and downs of adenovirus vectors. Bull N Y Acad Med 1996;73:53-8.
    • (1996) Bull N Y Acad Med , vol.73 , pp. 53-58
    • Ginsberg, H.S.1
  • 40
    • 29244491953 scopus 로고    scopus 로고
    • The effect of C3 transgene expression on actin and cell adhesions in cultured HTM cells and on outflow facility in organ cultured monkey eyes
    • Liu X, Hu Y, Filla MS, Gabelt BT, Brandt CR, Peters DP, Kaufman PL. The effect of C3 transgene expression on actin and cell adhesions in cultured HTM cells and on outflow facility in organ cultured monkey eyes. Mol Vis 2005;11:1112-21.
    • (2005) Mol Vis , vol.11 , pp. 1112-1121
    • Liu, X.1    Hu, Y.2    Filla, M.S.3    Gabelt, B.T.4    Brandt, C.R.5    Peters, D.P.6    Kaufman, P.L.7
  • 42
    • 0034212887 scopus 로고    scopus 로고
    • Adeno-associated virus vectors: Activity and applications in the CNS
    • Peel AL, Klein RL. Adeno-associated virus vectors: activity and applications in the CNS. J Neurosci Methods 2000;98:95-104.
    • (2000) J Neurosci Methods , vol.98 , pp. 95-104
    • Peel, A.L.1    Klein, R.L.2
  • 44
    • 0032788451 scopus 로고    scopus 로고
    • Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve
    • Guy J, Qi X, Muzyczka N, Hauswirth WW. Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve. Arch Ophthalmol 1999;117: 929-37.
    • (1999) Arch Ophthalmol , vol.117 , pp. 929-937
    • Guy, J.1    Qi, X.2    Muzyczka, N.3    Hauswirth, W.W.4
  • 45
    • 33750591238 scopus 로고    scopus 로고
    • Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis
    • Jacobson SG, Boye SL, Aleman TS, et al. Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis. Hum Gene Ther 2006;17:845-58.
    • (2006) Hum Gene Ther , vol.17 , pp. 845-858
    • Jacobson, S.G.1    Boye, S.L.2    Aleman, T.S.3
  • 46
    • 0032826773 scopus 로고    scopus 로고
    • Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model
    • Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR. Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model. J Virol 1999;73:8549-58.
    • (1999) J Virol , vol.73 , pp. 8549-8558
    • Hernandez, Y.J.1    Wang, J.2    Kearns, W.G.3    Loiler, S.4    Poirier, A.5    Flotte, T.R.6
  • 47
    • 0035687286 scopus 로고    scopus 로고
    • Genetic modification of human trabecular meshwork with lentiviral vectors
    • Loewen N, Fautsch MP, Peretz M,et al. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther 2001;12:2109-19.
    • (2001) Hum Gene Ther , vol.12 , pp. 2109-2119
    • Loewen, N.1    Fautsch, M.P.2    Peretz, M.3
  • 48
    • 4644311388 scopus 로고    scopus 로고
    • Transient immunosuppression stops rejection of virus-transduced enhanced green fluorescent protein in rabbit retina
    • Doi K, Kong J, Hargitai J, Goff SP, Gouras P. Transient immunosuppression stops rejection of virus-transduced enhanced green fluorescent protein in rabbit retina. J Virol 2004;78:11327-33.
    • (2004) J Virol , vol.78 , pp. 11327-11333
    • Doi, K.1    Kong, J.2    Hargitai, J.3    Goff, S.P.4    Gouras, P.5
  • 49
    • 15244346957 scopus 로고    scopus 로고
    • Retrovirus restriction by TRIM5alpha variants from Old World and New World primates
    • Song B, Javanbakht H, Perron M, Park D, Stremlau M, Sodroski J. Retrovirus restriction by TRIM5alpha variants from Old World and New World primates. J Virol 2005; 79:3930-7.
    • (2005) J Virol , vol.79 , pp. 3930-3937
    • Song, B.1    Javanbakht, H.2    Perron, M.3    Park, D.4    Stremlau, M.5    Sodroski, J.6
  • 50
    • 29744442932 scopus 로고    scopus 로고
    • Restriction of feline immunodeficiency virus by Ref1, Lv1, and primate TRIM5alpha proteins
    • Saenz DT, Teo W, Olsen JC, Poeschla EM. Restriction of feline immunodeficiency virus by Ref1, Lv1, and primate TRIM5alpha proteins. J Virol 2005;79:15175-88.
    • (2005) J Virol , vol.79 , pp. 15175-15188
    • Saenz, D.T.1    Teo, W.2    Olsen, J.C.3    Poeschla, E.M.4
  • 51
    • 30344463007 scopus 로고    scopus 로고
    • Gene therapy for neurodegenerative and ocular disease using lentiviral vectors
    • Ralph GS, Binley K, Wong LF, Azzouz M, Mazarakis ND. Gene therapy for neurodegenerative and ocular disease using lentiviral vectors. Clin Sci (Lond) 2006;110:37-46.
    • (2006) Clin Sci (Lond) , vol.110 , pp. 37-46
    • Ralph, G.S.1    Binley, K.2    Wong, L.F.3    Azzouz, M.4    Mazarakis, N.D.5
  • 52
    • 0347555450 scopus 로고    scopus 로고
    • Organ-specific gene expression in the rhesus monkey eye following intravenous non-viral gene transfer
    • Zhang Y, Schlachetzki F, Li JY, Boado RJ, Pardridge WM. Organ-specific gene expression in the rhesus monkey eye following intravenous non-viral gene transfer. Mol Vis 2003;9:465-72.
    • (2003) Mol Vis , vol.9 , pp. 465-472
    • Zhang, Y.1    Schlachetzki, F.2    Li, J.Y.3    Boado, R.J.4    Pardridge, W.M.5
  • 54
    • 14644423897 scopus 로고    scopus 로고
    • Effect of GDNF gene transfer into axotomized retinal ganglion cells using in vivo electroporation with a contact lens-type electrode
    • Ishikawa H, Takano M, Matsumoto N, Sawada H, Ide C, Mimura O, Dezawa M. Effect of GDNF gene transfer into axotomized retinal ganglion cells using in vivo electroporation with a contact lens-type electrode. Gene Ther 2005;12:289-98.
    • (2005) Gene Ther , vol.12 , pp. 289-298
    • Ishikawa, H.1    Takano, M.2    Matsumoto, N.3    Sawada, H.4    Ide, C.5    Mimura, O.6    Dezawa, M.7
  • 55
    • 4644371368 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Electroporation and other physical methods
    • Wells DJ. Gene therapy progress and prospects: electroporation and other physical methods. Gene Ther 2004;11:1363-9.
    • (2004) Gene Ther , vol.11 , pp. 1363-1369
    • Wells, D.J.1
  • 56
    • 0031935860 scopus 로고    scopus 로고
    • Introduction of DNA into the rat and primate trabecular meshwork by fusogenic liposomes
    • Hangai M, Tanihara H, Honda Y, Kaneda Y. Introduction of DNA into the rat and primate trabecular meshwork by fusogenic liposomes. Invest Ophthalmol Vis Sci 1998;39:509-16.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 509-516
    • Hangai, M.1    Tanihara, H.2    Honda, Y.3    Kaneda, Y.4


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