Targeted inactivation of the murine Abca3 gene leads to respiratory failure in newborns with defective lamellar bodies

Biochemical and Biophysical Research Communications

Volumn 359, Issue 4, 2007, Pages 947-951

  Hammel, Markus ^a   Michel, Geert ^b   Hoefer, Christina ^b   Klaften, Matthias ^b   Müller Höcker, Josef ^c   de Angelis, Martin Hrabé ^b   Holzinger, Andreas ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

ABCA3; Atelectasis; Lamellar body; Newborn; Respiratory distress syndrome; Surfactant; Transgenic mouse model

Indexed keywords

ABC TRANSPORTER; PROTEIN ABCA3; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; INTERSTITIAL LUNG DISEASE; LAMELLAR BODY; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY FAILURE;

ANIMALS; ANIMALS, NEWBORN; ATP-BINDING CASSETTE TRANSPORTERS; GENE SILENCING; GENE TARGETING; LUNG; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RESPIRATORY INSUFFICIENCY;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 34250646618     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.219     Document Type: Article

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