Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors

Experimental Hematology

Volumn 35, Issue 7, 2007, Pages 1026-1037

  Borneo, Jovencio ^a   Munugalavadla, Veerendra ^a   Sims, Emily C ^a   Vemula, Sasidhar ^a   Orschell, Christie M ^a   Yoder, Merv ^a   Kapur, Reuben ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); GELATINASE B; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ENZYME REGULATION; HEMATOPOIETIC STEM CELL; INTRACELLULAR TRANSPORT; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; STRUCTURAL PROTEOMICS;

ANIMALS; CELL MOVEMENT; CHEMOKINES, CXC; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; MATRIX METALLOPROTEINASE 1; MICE; MICE, INBRED C57BL; RECEPTORS, CHEMOKINE; SRC-FAMILY KINASES; VASCULAR CELL ADHESION MOLECULE-1;

MUS;

EID: 34250645811     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.03.017     Document Type: Article

References (25)

1. Abkowitz J.L., Robinson A.E., Kale S., Long M.W., and Chen J. Mobilization of hematopoietic stem cells during homeostasis and after cytokine exposure. Blood 102 (2003) 1249-1253
2. Wright D.E., Wagers A.J., Gulati A.P., Johnson F.L., and Weissman I.L. Physiological migration of hematopoietic stem and progenitor cells. Science 294 (2001) 1933-1936
3. Villalon L., Odriozola J., Larana J.G., et al. Autologous peripheral blood progenitor cell transplantation with <2 × 10(6) CD34(+)/kg: an analysis of variables concerning mobilisation and engraftment. Hematol J 1 (2000) 374-381
4. Roberts A.W., DeLuca E., Begley C.G., Basser R., Grigg A.P., and Metcalf D. Broad inter-individual variations in circulating progenitor cell numbers induced by granulocyte colony-stimulating factor therapy. Stem Cells 13 (1995) 512-516
5. Pruijt J.F., Verzaal P., van Os R., et al. Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice. Proc Natl Acad Sci U S A 99 (2002) 6228-6233
6. Pelus L.M., Bian H., King A.G., and Fukuda S. Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GRObeta/CXCL2 and GRObetaT/CXCL2delta4. Blood 103 (2004) 110-119
7. Liu F., Poursine-Laurent J., and Link D.C. Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF. Blood 95 (2000) 3025-3031
8. Levesque J.P., Takamatsu Y., Nilsson S.K., Haylock D.N., and Simmons P.J. Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood 98 (2001) 1289-1297
9. Levesque J.P., Hendy J., Takamatsu Y., Williams B., Winkler I.G., and Simmons P.J. Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment. Exp Hematol 30 (2002) 440-449
10. Petit I., Szyper-Kravitz M., Nagler A., et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol 3 (2002) 687-694
11. van Pel M., van Os R., Velders G.A., et al. Serpina1 is a potent inhibitor of IL-8-induced hematopoietic stem cell mobilization. Proc Natl Acad Sci U S A 103 (2006) 1469-1474
12. Pruijt J.F., Fibbe W.E., Laterveer L., et al. Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9). Proc Natl Acad Sci U S A 96 (1999) 10863-10868
13. Levesque JP, Liu F, Simmons PJ, et al. Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood. 1004;104:65-72.
14. Shen H., Cheng T., Olszak I., et al. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. J Immunol 166 (2001) 5027-5033
15. Hattori K., Heissig B., Tashiro K., et al. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 97 (2001) 3354-3360
16. Foudi A., Jarrier P., Zhang Y., et al. Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice. Blood 107 (2006) 2243-2251
17. Papayannopoulou T., and Nakamoto B. Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci U S A 90 (1993) 9374-9378
18. Craddock C.F., Nakamoto B., Andrews R.G., Priestley G.V., and Papayannopoulou T. Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice. Blood 90 (1997) 4779-4788
19. Kikuta T., Shimazaki C., Ashihara E., et al. Mobilization of hematopoietic primitive and committed progenitor cells into blood in mice by anti-vascular adhesion molecule-1 antibody alone or in combination with granulocyte colony-stimulating factor. Exp Hematol 28 (2000) 311-317
20. Scott L.M., Priestley G.V., and Papayannopoulou T. Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing. Mol Cell Biol 23 (2003) 9349-9360
21. Ulyanova T., Scott L.M., Priestley G.V., et al. VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin. Blood 106 (2005) 86-94
22. Levesque J.P., Hendy J., Takamatsu Y., Simmons P.J., and Bendall L.J. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest 111 (2003) 187-196
23. Mermel C.H., McLemore M.L., Liu F., et al. Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis. Blood 108 (2006) 2562-2568
24. Croker B.A., Metcalf D., Robb L., et al. SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity 20 (2004) 153-165
25. Saijo K., Schmedt C., Su I.H., et al. Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nat Immunol 4 (2003) 274-279