Effects of age and gender on shortening velocity and myosin isoforms in single rat muscle fibres

Acta Physiologica Scandinavica

Volumn 163, Issue 1, 1998, Pages 33-40

  Degens, H ^a   Yu, F ^a,b   Li, X ^a   Larsson, L ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

M. extensor digitorum longus; M. soleus; Skinned fibres; Slack test

Indexed keywords

MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN;

ADOLESCENT; AGED; AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; FEMALE; GENDER; MALE; MUSCLE FIBER CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SKINNED MUSCLE FIBER; SLOW MUSCLE FIBER; SOLEUS MUSCLE;

AGING; ANIMALS; FEMALE; HINDLIMB; MALE; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; MYOSINS; RATS; RATS, WISTAR; SEX CHARACTERISTICS; TIME FACTORS;

EID: 0031746219     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201x.1998.00329.x     Document Type: Article

References (35)

1. Ansved, T. & Larsson, L. 1989. Effects of ageing on enzyme-histochemical, morphometrical and contractile properties of the soleus muscle in the rat. J Neurol Sci 93, 105-124.
2. Balagopal, P., Rooyackers, O.E., Adey, D.B., Ades, P.A. & Nair, K.S. 1997. Effects on aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol. 273, E790-E800.
3. Bárány, M. 1967. ATPase activity of myosin correlated with speed of shortening. J Gen Physiol 50, 197-218.
4. Beltran Niclos, B., Welsh, L., Sarwar, R. & Rutherford, O.M. 1995. Gender and age comparisons of the contractile properties of the human quadriceps muscle. J Physiol Lond 483, 131P.
5. Bottinelli, R., Betto, R., Schiaffino, S. & Reggiani, C. 1994. Unloaded shortening velocity and myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibres. J Physiol Lond 478, 341-349.
6. Brooks, S.V. & Faulkner, J.A. 1988. Contractile properties of skeletal muscles from young and adult and aged mice. J Physiol Lond 404, 71-82.
7. Cartee, G.D. 1995. What insights into age-related changes in skeletal muscle are provided by animal models? J Geront 50A, 137-141.
8. Edman, K.A.P. 1979. The velocity of unloaded shortening and its relation to sarcomere length and isometric force in venebrate muscle fibres. J Physiol Lond 291, 143-159.
9. Fitts, R.H., Troup, J.P., Witzman, F.A. & Holloszy, J.O. 1984. The effect of ageing and exercise on skeletal muscle function. Mech Ageing Dev 27, 161-172.
10. Frontera, W.R. & Larsson, L. 1997. Contractile studies of single skeletal muscle fibers: a comparison of different permeabilization and storage techniques and two different muscles. Muscle Nerve 20, 948-952.
11. Greaser, M.L., Moss, R.L. & Reiser, P.J. 1988. Variations in contractile properties of rabbit single muscle fibres in relation to troponin T isoforms and myosin light chains. J Physiol Lond 406, 85-98.
12. Izumo, S., Nadal-Ginard, B. & Mahdavi, V. 1986. All members of the MHC multigene family respond to thyroid hormone in a highly tissue-specific manner. Sci 231, 597-600.
13. Larsson, L., Ansved, T., Edström, L., Gorza, L. & Schiaffino, S. 1991. Effects of age on physiological, immunological and biochemical properties of fast-twitch single motor units in the rat. J Physiol Lond 443, 257-275.
14. Larsson, L., Li, X. & Frontera, W.R. 1997. Effects of ageing on shortening velocity and myosin isoform composition in single human skeletal muscle cells. Am J Physiol 272, C638-C649.
15. Larsson, L. & Moss, R. 1993. Maximum velocity of unloaded shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. J Physiol Lond 472, 595-614.
16. Larsson, L., Müller, U., Li, X. & Schiaffino, S. 1995. Thyroid hormone regulation of myosin heavy chain isoform composition in young and old rats, with special reference to IIX myosin. Acta Physiol Scand 153, 109-116.
17. Larsson, L. & Salviati, G. 1989. Effects of age on the calcium transport activity of the sarcoplasmic reticulum in fast- and slow-twitch muscle fibres in the rat. J Physiol Lond 419, 253-264.
18. Larsson, L. & Yu, F. 1997. Gender-related differences in the regulatory influence of thyroid hormone on the expression of myosin isoforms in young and old rats. Acta Physiol Scand 159, 81-89.
19. Li, X. & Larsson, L. 1996. Maximum shortening velocity and myosin isoforms in single muscle fibres from young and old rats. Am J Physiol 270, C352-C360.
20. Madsen, O.R., Schaadt, O., Bliddal, H., Egsmose, C. & Sylvest, J. 1993. Relationship between quadriceps strength and bone mineral density of the proximal tibia and distal forearm in women. J Bone Miner Res 8, 1439-1444.
21. Miller, A.E.J., MacDougall, J.D., Tarnopolsky, M.A. & Sale, D.G. 1993. Gender differences in strength and muscle fiber characteristics. Eur J Appl Physiol 66, 254-262.
22. Moss, R.L. 1979 Sarcomere length-tension relations in frog skinned muscle fibres during calcium activation at short lengths. J Physiol Lond, 292, 177-192. 1993.
23. Phillips, S.K., Rook, K.M., Siddle, N.C., Bruce, S.A. & Woledge, R.C. 1996a. Muscle weakness in women occurs at an earlier age than in men, but strength is preserved by hormone replacement therapy. Clin Sci 84, 85-98.
24. Phillips, S.K., Sanderson, A.G., Birch, K., Bruce, A.A. & Woledge, R.C. 1996b. Changes in maximal voluntary force of human adductor pollicis muscle during the menstrual cycle. J Physiol Lond 496, 551-557.
25. Rantanen, T., Era, P. & Heikkinen, E. 1996. Maximal isometric knee extension strength and stair- mounting ability in 75- and 80-year-old men and women. Scan J Rehab Med 28, 89-93.
26. Rattan, S.I.S. 1996. Synthesis, modifications, and turnover of proteins during aging. Exp Geront 31, 33-47.
27. Reiser, P.J., Moss, R.L., Giulian, G.G. & Greaser, M.L. 1985. Shortening velocity in single fibers from adult rabbit soleus muscles is correlated with myosin heavy chain composition. J Biol Chem 260, 9077-9080.
28. Rome, L.C., Sosnicki, A.A. & Goble, D.O. 1990. Maximum velocity of shortening of three fibre types from horse soleus muscle: implications for scaling with body size. J Physiol 431, 173-185.
29. Rosenkranz-Weiss, P., Tomek, R.J., Mathew, J. & Eghbali, M. 1994. Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. J Mol Cell Cardiol 26, 261-270.
30. Sarwar, R., Beltran Niclos, B. & Rutherford, O.M. 1996. Changes in muscle strength, relaxation rate and fatiguability during the human menstrual cycle. J Physiol Lond 493, 267-272.
31. Schiaffino, S. & Reggiani, C. 1996. Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev 76, 371-423.
32. Schluter, J.M. & Fitts, R.H. 1994. Shortening velocity and ATPase activity of rat skeletal muscle fibers: effects of endurance exercise training. Am J Physiol 266, C1699-C1713.
33. Sugiura, T., Matoba, H., Miyata, H., Kawai, Y. & Murakami, M. 1992. Myosin heavy chain isoform transition in ageing fast and slow muscles of the rat. Acta Physiol Scand 144, 419-423.
34. Sweeney, H.L., Kushmerick, M.J., Mabuchi, K., Sréter, F.A. & Gergely, J. 1988. Myosin alkali light chain and heavy chain variations correlate with altered shortening velocity of isolated skeletal muscle fibers. J Biol Chem 263, 9034-9039.
35. Zhu, Y.-S., Yen, P.M., Chin, W.W. & Pfaff, D.W. 1996. Estrogen and thyroid hormone interaction on regulation of gene expression. Proc Natl Acad Sci 93, 12587-12592.