Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps

Virology Journal

Volumn 4, Issue , 2007, Pages

  Ternette, Nicola ^a   Stefanou, Daniela ^a   Kuate, Seraphin ^a   Überla, Klaus ^a   Grunwald, Thomas ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RNA POLYMERASE II; G PROTEIN, VESICULAR STOMATITIS VIRUS; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CODON; CYTOPLASM; GENE INSERTION; INTRON; MOLECULAR MECHANICS; MUTATION; NONHUMAN; OPEN READING FRAME; PLASMID; POLYADENYLATION; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RNA VIRUS; VESICULAR STOMATITIS VIRUS; VIRUS REPLICATION; BIOSYNTHESIS; CELL LINE; CHEMISTRY; EXON; GENE EXPRESSION; GENE VECTOR; GENETIC PROCEDURES; GENETICS; HUMAN; METABOLISM; REGULATORY RNA SEQUENCE;

ANIMALIA; EUKARYOTA; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS; RNA VIRUSES; VESICULAR STOMATITIS VIRUS;

CELL LINE; CODON; CYTOPLASM; EXONS; GENE EXPRESSION; GENETIC TECHNIQUES; GENETIC VECTORS; HUMANS; INTRONS; MEMBRANE GLYCOPROTEINS; PLASMIDS; RESPIRATORY SYNCYTIAL VIRUSES; RNA 3' POLYADENYLATION SIGNALS; RNA POLYMERASE II; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL ENVELOPE PROTEINS; VIRAL FUSION PROTEINS;

EID: 34250613923     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-4-51     Document Type: Article

References (41)

1. Codon usage limitation in the expression of HIV-1 envelope glycoprotein. J Haas EC Park B Seed, Curr Biol 1996 6 315 324 10.1016/S0960-9822(02)00482-7 8805248
2. Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors. R Wagner M Graf K Bieler H Wolf T Grunwald P Foley K Uberla, Hum Gene Ther 2000 11 2403 2413 10.1089/104303400750038507 11096444
3. Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay. CJ Morton R Cameron LJ Lawrence B Lin M Lowe A Luttick A Mason J Kimm-Breschkin MW Parker J Ryan M Smout J Sullivan SP Tucker PR Young, Virology 2003 311 275 288 10.1016/S0042-6822(03)00115-6 12842618
4. A second post-transcriptional trans-activator gene required for HTLV-III replication. J Sodroski WC Goh C Rosen A Dayton E Terwilliger W Haseltine, Nature 1986 321 412 417 10.1038/321412a0 3012355
5. Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. S Schwartz BK Felber GN Pavlakis, J Virol 1992 66 150 159 1727477
6. Transcriptional control of the RNA-dependent RNA polymerase of vesicular stomatitis virus. JN Barr SP Whelan GW Wertz, Biochim Biophys Acta 2002 1577 337 353 12213662
7. Recombinant vesicular stomatitis viruses from DNA. ND Lawson EA Stillman MA Whitt JK Rose, Proc Natl Acad Sci USA 1995 92 4477 4481 7753828 10.1073/pnas.92.10.4477
8. Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development. PL Collins MG Hill E Camargo H Grosfeld RM Chanock BR Murphy, Proc Natl Acad Sci USA 1995 92 11563 11567 8524804 10.1073/pnas.92.25.11563
9. Respiratory syncytial virus: reverse genetics and vaccine strategies. PL Collins BR Murphy, Virology 2002 296 204 211 10.1006/viro.2002.1437 12069519
10. Immunopathogenesis of vaccine-enhanced RSV disease. PJ Openshaw FJ Culley W Olszewska, Vaccine 2001 20 Suppl 1 S27 S31 10.1016/S0264-410X(01)00301-2 11587806
11. Immune responses and disease enhancement during respiratory syncytial virus infection. PJ Openshaw JS Tregoning, Clin Microbiol Rev 2005 18 541 555 16020689 10.1128/CMR.18.3.541-555.2005
12. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. M Boshart F Weber G Jahn K Dorsch-Hasler B Fleckenstein W Schaffner, Cell 1985 41 521 530 10.1016/S0092-8674(85)80025-8 2985280
13. A highly modular cloning vector for the analysis of eukaryotic genes and gene regulatory elements. DS Pfarr G Sathe ME Reff, DNA 1985 4 461 467 3004852
14. Differential effects of polyadenylation regions on gene expression in mammalian cells. DS Pfarr LA Rieser RP Woychik FM Rottman M Rosenberg ME Reff, DNA 1986 5 115 122 2872023
15. From birth to death: the complex lives of eukaryotic mRNAs. MJ Moore, Science 2005 309 1514 1518 10.1126/science.1111443 16141059
16. Nonsense-mediated mRNA decay in mammals. LE Maquat, J Cell Sci 2005 118 1773 1776 10.1242/jcs.01701 15860725
17. How introns influence and enhance eukaryotic gene expression. HH Le A Nott MJ Moore, Trends Biochem Sci 2003 28 215 220 10.1016/S0968-0004(03)00052-5 12713906
18. Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements. BP Sleckman JR Gorman FW Alt, Annu Rev Immunol 1996 14 459 481 10.1146/annurev.immunol.14.1.459 8717521
19. Simian virus 40 late transcripts lacking excisable intervening sequences are defective in both stability in the nucleus and transport to the cytoplasm. WS Ryu JE Mertz, J Virol 1989 63 4386 4394 2550672
20. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. HH Le D Gatfield E Izaurralde MJ Moore, EMBO J 2001 20 4987 4997 11532962 10.1093/emboj/20.17.4987
21. Nuclear RNA export. BR Cullen, J Cell Sci 2003 116 587 597 10.1242/jcs.00268 12538759
22. Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions. HH Le MJ Moore LE Maquat, Genes Dev 2000 14 1098 1108 10809668
23. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. U Schubert LC Anton J Gibbs CC Norbury JW Yewdell JR Bennink, Nature 2000 404 770 774 10.1038/35004754 10783891
24. At the crossroads of cell biology and immunology: DRiPs and other sources of peptide ligands for MHC class I molecules. JW Yewdell U Schubert JR Bennink, J Cell Sci 2001 114 845 851 11181168
25. Protection against respiratory syncytial virus infection by DNA immunization. X Li S Sambhara CX Li M Ewasyshyn M Parrington J Caterini O James G Cates RP Du M Klein, J Exp Med 1998 188 681 688 10.1084/jem.188.4.681 9705950
26. DNA encoding the attachment (G) or fusion (F) protein of respiratory syncytial virus induces protection in the absence of pulmonary inflammation. GP Bembridge N Rodriguez R Garcia-Beato C Nicolson JA Melero G Taylor, J Gen Virol 2000 81 2519 2523 10993942
27. Respiratory syncytial virus infection of gene gun vaccinated mice induces Th2-driven pulmonary eosinophilia even in the absence of sensitisation to the fusion (F) or attachment (G) protein. GP Bembridge N Rodriguez R Garcia-Beato C Nicolson JA Melero G Taylor, Vaccine 2000 19 1038 1046 10.1016/S0264-410X(00) 00344-3 11137237
28. An assessment of different DNA delivery systems for protection against respiratory syncytial virus infection in the murine model: gene-gun delivery induces IgG in the lung. JA Tree G Bembridge S Hou G Taylor E Fashola-Stone J Melero MP Cranage, Vaccine 2004 22 2438 2443 10.1016/j.vaccine.2003.11.069 15193407
29. Immune induction and modulation in mice following immunization with DNA encoding F protein of respiratory syncytial virus. EK Park BY Soh YS Jang JH Park GH Chung, Mol Cells 2001 12 50 56 11561730
30. A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal. J Wilusz T Shenk, Mol Cell Biol 1990 10 6397 6407 1701018
31. Sequence and position requirements for uridylate-rich downstream elements of polyadenylation signals. ZF Chou F Chen J Wilusz, Nucleic Acids Res 1994 22 2525 2531 7518915 10.1093/nar/22.13.2525
32. Iduronic acid-containing glycosaminoglycans on target cells are required for efficient respiratory syncytial virus infection. LK Hallak PL Collins W Knudson ME Peeples, Virology 2000 271 264 275 10.1006/viro.2000.0293 10860881
33. HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. RA Fouchier BE Meyer JH Simon U Fischer MH Malim, EMBO J 1997 16 4531 4539 9303297 10.1093/emboj/16.15.4531
34. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. M Kozak, Nucleic Acids Res 1984 12 857 872 6694911 10.1093/nar/12.2.857
35. Multiple effects of codon usage optimization on expression and immunogenicity of DNA candidate vaccines encoding the human immunodeficiency virus type 1 Gag protein. L Deml A Bojak S Steck M Graf J Wild R Schirmbeck H Wolf R Wagner, J Virol 2001 75 10991 11001 11602739 10.1128/JVI.75.22.10991- 11001.2001
36. Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus. T Schnell P Foley M Wirth J Munch K Uberla, Hum Gene Ther 2000 11 439 447 10.1089/10430340050015905 10697118
37. Development of a self-inactivating lentivirus vector. H Miyoshi U Blomer M Takahashi FH Gage IM Verma, J Virol 1998 72 8150 8157 9733856
38. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. RB DuBridge P Tang HC Hsia PM Leong JH Miller MP Calos, Mol Cell Biol 1987 7 379 387 3031469
39. Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes. M Simm M Shahabuddin W Chao JS Allan DJ Volsky, J Virol 1995 69 4582 4586 7769728
40. Effect of respiratory syncytial virus-antibody complexes on cytokine (IL-8, IL-6, TNF-alpha) release and respiratory burst in human granulocytes. R Arnold F Werner B Humbert H Werchau W Konig, Immunology 1994 82 184 191 7927487
41. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. GI Evan GK Lewis G Ramsay JM Bishop, Mol Cell Biol 1985 5 3610 3616 3915782