Screening a novel class of anticoagulants for multi-organ toxicity using Fischer 344 rats: Involvement of clinical and anatomic pathologists in the early drug development process

Veterinary Clinical Pathology

Volumn 36, Issue 2, 2007, Pages 123-136

  Schultze, A Eric ^a   Sullivan, John M ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Anticoagulant; Clinical pathology; Enterotoxicity; Hepatobiliary toxicity; Phospholipidosis; Safety assessment; Toxicology

Indexed keywords

ANTICOAGULANT AGENT;

ADRENAL GLAND; ANIMAL; ARTICLE; BLOOD CLOTTING; BODY WEIGHT; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; FEMALE; FISCHER 344 RAT; INTESTINE; LIVER; METHODOLOGY; PATHOLOGY; RAT; THYMUS; VETERINARY MEDICINE;

ADRENAL GLANDS; ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; INTESTINES; LIVER; PATHOLOGY, VETERINARY; RATS; RATS, INBRED F344; THYMUS GLAND; VETERINARIANS;

RATTUS;

EID: 34250364988     PISSN: 02756382     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-165X.2007.tb00198.x     Document Type: Article

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