Epididymal and Systemic Phospholipidosis in Rats and Dogs Treated with the Dopamine D3 Selective Antagonist PNU-177864

Toxicologic Pathology

Volumn 32, Issue 3, 2004, Pages 326-332

  Rudmann, Daniel G ^a   Mcnerney, Mary E ^a   Vandereide, Stacey L ^b   Schemmer, Joyce K ^b   Eversole, Robert R ^b   Vonderfecht, Steven L ^a  

^a PFIZER INC   (United States)

^b WESTERN MICHIGAN UNIVERSITY   (United States)

Author keywords

biomarker; D3 receptors; dog; Dopamine; phospholipidosis; rat; toxicity

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CREATINE KINASE; DOPAMINE 3 RECEPTOR BLOCKING AGENT; PNU 177864; UNCLASSIFIED DRUG;

ADRENAL CORTEX; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; DOG; DRUG SAFETY; EPIDIDYMAL PHOSPHOLIPIDOSIS; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; HYPOPHYSIS; LIPIDOSIS; LIVER; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE; LYMPHOID TISSUE; MALE; NONHUMAN; PEYER PATCH; PLASMA CELL; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; SPLEEN; SYSTEMIC PHOSPHOLIPIDOSIS; TOXICITY TESTING;

ANIMALS; BIOLOGICAL MARKERS; DOGS; DOPAMINE ANTAGONISTS; DRUG EVALUATION, PRECLINICAL; EPIDIDYMIS; EPITHELIAL CELLS; LIPIDOSES; LYMPHOCYTES; MALE; MICROSCOPY, ELECTRON; MUSCLE, SKELETAL; PHOSPHOLIPIDS; RATS; SPECIES SPECIFICITY; SPERM MOTILITY; SPERMATOZOA; VACUOLES;

ANIMALIA; CANIS FAMILIARIS; VERTEBRATA;

EID: 2542434899     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230490431754     Document Type: Article

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