Nifurtimox nitroreductase activity in different cellular fractions from male rat pancreas. Biochemical and ultrastructural alterations

Life Sciences

Volumn 81, Issue 2, 2007, Pages 144-152

  de Mecca, María Montalto ^a   Fanelli, Silvia L ^a   Bartel, Laura C ^a   de Castro, Carmen R ^a   Díaz, Edith G ^a   Castro, José A ^a  

^a Centro de Investigaciones Toxicologicos   (Argentina)

Author keywords

Chagas' disease; Nifurtimox; Nitroreductase; Oxidative stress; Pancreas

Indexed keywords

ALLOPURINOL; AMYLASE; CARBONYL DERIVATIVE; GLUCOSE; HYPOXANTHINE; LIPID HYDROPEROXIDE; NIFURTIMOX; NITROREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TERT BUTYL HYDROPEROXIDE;

ACINAR CELL; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL ULTRASTRUCTURE; CHAGAS DISEASE; CHEMOLUMINESCENCE; DRUG METABOLISM; DRUG STRUCTURE; DRUG TISSUE LEVEL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS; RAT; REDUCTION;

ANIMALS; CYTOSOL; INSULIN-SECRETING CELLS; LUMINESCENCE; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSOMES; NIFURTIMOX; NITROREDUCTASES; PANCREAS; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS; SULFHYDRYL COMPOUNDS; SUPEROXIDES; TERT-BUTYLHYDROPEROXIDE;

RATTUS;

EID: 34250342631     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.04.033     Document Type: Article

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