Oligomerization of the human prion protein proceeds via a molten globule intermediate

Journal of Biological Chemistry

Volumn 282, Issue 9, 2007, Pages 6300-6307

  Gerber, Remo ^a   Tahiri Alaoui, Abdessamad ^b,c   Hore, P J ^a   James, William ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRILS; COMPATIBLE PRECURSORS; MOLECULAR MECHANISMS;

CONFORMATIONS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; OLIGOMERS;

PROTEINS;

AMYLOID; APOMYOGLOBIN; MOLTEN GLOBULE INTERMEDIATE; MONOMER; OLIGOMER; PRION PROTEIN; PROTEINASE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; DEGENERATIVE DISEASE; HUMAN; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; PRION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; REACTION ANALYSIS; CHEMISTRY; DIMERIZATION; PROTEIN SECONDARY STRUCTURE;

AMYLOID; DIMERIZATION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

EID: 34250330794     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608926200     Document Type: Article

References (46)

1. Prusiner, S. B. (1996) Trends Biochem. Sci. 21, 482-487
2. Weissmann, C. (1996) FEBS Lett. 389, 3-11
3. Prusiner, S. B. (1982) Science 216, 136-144
4. Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., and Wuthrich, K. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 145-150
5. Stahl, N., Baldwin, M. A., Teplow, D. B., Hood, L., Gibson, B. W., Burlingame, A. L., and Prusiner, S. B. (1993) Biochemistry 32, 1991-2002
6. Baskakov, I. V., Legname, G., Baldwin, M. A., Prusiner, S. B., and Cohen, F. E. (2002) J. Biol. Chem. 277, 21140-21148
7. Lu, B. Y., and Chang, J. Y. (2001) Biochemistry 40, 13390-13396
8. Oesch, B., Westaway, D., Walchli, M., McKinley, M. P., Kent, S. B., Aebersold, R., Barry, R. A., Tempst, P., Teplow, D. B., Hood, L. E., Prusiner, S. B., and Weissmann, C. (1985) Cell 40, 735-746
9. Tahiri-Alaoui, A., Gill, A. C., Disterer, P., and James, W. (2004) J. Biol. Chem. 279, 31390-31397
10. Tahiri-Alaoui, A., Sim, V. L., Caughey, B., and James, W. (2006) J. Biol. Chem. 281, 34171-34178
11. Cohen, F. E., Pan, K. M., Huang, Z., Baldwin, M., Fletterick, R. J., and Prusiner, S. B. (1994) Science 264, 530-531
12. Sokolowski, F., Modler, A. J., Masuch, R., Zirwer, D., Baier, M., Lutsch, G., Moss, D. A., Gast, K., and Naumann, D. (2003) J. Biol. Chem. 278, 40481-40492
13. Jackson, G. S., Hosszu, L. L., Power, A., Hill, A. F., Kenney, J., Saibil, H., Craven, C. J., Waltho, J. P., Clarke, A. R., and Collinge, J. (1999) Science 283, 1935-1937
14. Maiti, N. R., and Surewicz, W. K. (2001) J. Biol. Chem. 276, 2427-2431
15. Hosszu, L. L., Jackson, G. S., Trevitt, C. R., Jones, S., Batchelor, M., Bhelt, D., Prodromidou, K., Clarke, A. R., Waltho, J. P., and Collinge, J. (2004) J. Biol. Chem. 279, 28515-28521
16. Chen, Y. H., Yang, J. T., and Martinez, H. M. (1972) Biochemistry 11, 4120-4131
17. Jones, J. A., Wilkins, D. K., Smith, L. J., and Dobson, C. M. (1997) J. Biomol. NMR 10, 199
18. Merrill, M. R. (1993) J. Magn. Reson. Series A 103, 223
19. Wilkins, D. K., Grimshaw, S. B., Receveur, V., Dobson, C. M., Jones, J. A., and Smith, L. J. (1999) Biochemistry 38, 16424-16431
20. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
21. Keller, R. (2004) The Computer Aided Resonance Assignment Tutorial, CANTINA Verlag, Goldau, Switzerland
22. Morillas, M., Vanik, D. L., and Surewicz, W. K. (2001) Biochemistry 40, 6982-6987
23. Stryer, L. (1968) Science 162, 526-533
24. Safar, J., Roller, P. P., Gajdusek, D. C., and Gibbs, C. J., Jr. (1994) Biochemistry 33, 8375-8383
25. Semisotnov, G. V., Rodionova, N. A., Razgulyaev, O. I., Uversky, V. N., Gripas, A. F., and Gilmanshin, R. I. (1991) Biopolymers 31, 119-128
26. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1991) J. Mol. Biol. 222, 311-333
27. Qin, K., Yang, D. S., Yang, Y., Chishti, M. A., Meng, L. J., Kretzschmar, H. A., Yip, C. M., Fraser, P. E., and Westaway, D. (2000) J. Biol. Chem. 275, 19121-19131
28. Apetri, A. C., and Surewicz, W. K. (2002) J. Biol. Chem. 277, 44589-44592
29. Nicholson, E. M., Mo, H., Prusiner, S. B., Cohen, F. E., and Marqusee, S. (2002) J. Mol. Biol. 316, 807-815
30. Kuwata, K., Li, H., Yamada, H., Legname, G., Prusiner, S. B., Akasaka, K., and James, T. L. (2002) Biochemistry 41, 12277-12283
31. Martins, S. M., Chapeaurouge, A., and Ferreira, S. T. (2003) J. Biol. Chem. 278, 50449-50455
32. Cohen, F. E., and Prusiner, S. B. (1998) Annu. Rev. Biochem. 67, 793-819
33. Novitskaya, V., Bocharova, O. V., Bronstein, I., and Baskakov, I. V. (2006) J. Biol. Chem. 281, 13828-13836
34. Baskakov, I. V., Legname, G., Gryczynski, Z., and Prusiner, S. B. (2004) Protein Sci. 13, 586-595
35. Arnold, J. E., Tipler, C., Laszlo, L., Hope, J., Landon, M., and Mayer, R. J. (1995) J. Pathol. 176, 403-411
36. McKinley, M. P., Taraboulos, A., Kenaga, L., Serban, D., Stieber, A., DeArmond, S. J., Prusiner, S. B., and Gonatas, N. (1991) Lab. Investig. 65, 622-630
37. Wuthrich, K. (1986) NMR of Proteins and Nucleic Acids, John Wiley & Sons, Inc., New York
38. Zahn, R., von Schroetter, C., and Wuthrich, K. (1997) FEBS Lett. 417, 400-404
39. Redfield, C., Schulman, B. A., Milhollen, M. A., Kim, P. S., and Dobson, C. M. (1999) Nat. Struct. Biol. 6, 948-952
40. Schulman, B. A., Kim, P. S., Dobson, C. M., and Redfield, C. (1997) Nat. Struct. Biol. 4, 630-634
41. Redfield, C. (1999) Curr. Biol. 9, R313
42. Redfield, C. (2004) Methods (Amst.) 34, 121-132
43. Baskakov, I., Disterer, P., Breydo, L., Shaw, M., Gill, A., James, W., and Tahiri-Alaoui, A. (2005) FEBS Lett. 579, 2589-2596
44. Tahiri-Alaoui, A., and James, W. (2005) Protein Sci. 14, 942-947
45. Baskakov, I. V., Legname, G., Prusiner, S. B., and Cohen, F. E. (2001) J. Biol. Chem. 276, 19687-19690
46. Govaerts, C., Wille, H., Prusiner, S. B., and Cohen, F. E. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 8342-8347