4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives as non-peptidic selective δ-opioid agonists with potential anxiolytic/antidepressant properties. Part 2

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 14, 2007, Pages 3860-3863

  Trabanco, Andrés A ^a,b   Aerts, Nancy ^a,c   Alvarez, Rosa M ^a,b   Andrés, José I ^a,b   Boeckx, Inge ^a,c   Fernández, Javier ^a,b   Gómez, Antonio ^a,b   Janssens, Frans E ^a,c   Leenaerts, Joseph E ^a,c   De Lucas, Ana I ^a,b   Matesanz, Encarna ^a,b   Steckler, Thomas ^a,c   Pullan, Shirley ^a,c  

^a JOHNSON AND JOHNSON   (United States)

^b Division of Janssen Cilag SA   (Spain)

^c JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

Agonist; Antidepressant; Anxiolytic; Opioid

Indexed keywords

4 PHENYL 4 (1H IMIDAZOL 2 YL)PIPERIDINE DERIVATIVE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; EXPERIMENTAL TEST; MOUSE; NONHUMAN; REACTION ANALYSIS; RECEPTOR AFFINITY; STRUCTURE ANALYSIS; TAIL SUSPENSION TEST; TRANQUILIZING ACTIVITY; ULTRASOUND; VOCALIZATION;

ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; PIPERIDINES; RECEPTORS, OPIOID, DELTA;

EID: 34250330260     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.012     Document Type: Article

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