4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives, a novel class of selective δ-opioid agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 1, 2006, Pages 146-149

  Trabanco, Andrés A ^a,b   Pullan, Shirley ^a,c   Alonso, José M ^a,b   Alvarez, Rosa M ^a,b   Andrés, José I ^a,b   Boeckx, Inge ^a,c   Fernández, Javier ^a,b   Gómez, Antonio ^a,b   Iturrino, Laura ^a,b   Janssens, Frans E ^a,c   Leenaerts, Joseph E ^a,c   De Lucas, Ana I ^a,b   Matesanz, Encarna ^a,b   Meert, Theo ^a,c   Steckler, Thomas ^a,c  

^a JOHNSON AND JOHNSON   (United States)

^b Division of Janssen Cilag SA   (Spain)

^c JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

agonist; Opioid

Indexed keywords

DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; PIPERIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

BINDING, COMPETITIVE; DRUG DESIGN; DRUG INDUSTRY; IMIDAZOLES; KINETICS; MODELS, CHEMICAL; PEPTIDES; PIPERIDINES; RECEPTORS, OPIOID, DELTA; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 27744506551     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.025     Document Type: Article

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