Fluorescence in situ hybridization analysis of 110 hematopoietic disorders with chromosome 5 abnormalities: do de novo and therapy-related myelodysplastic syndrome-acute myeloid leukemia actually differ?

Cancer Genetics and Cytogenetics

Volumn 176, Issue 1, 2007, Pages 1-21

  Lessard, M ^a,b   Helias C ^a   Struski, S ^a   Perrusson, N ^b   Uettwiller, F ^a   Mozziconacci, M J ^c   Lafage Pochitaloff, M ^c   Dastugue, N ^d   Terre C ^e   Brizard, F ^f   Cornillet Lefebvre, P ^g   Mugneret, F ^h   Barin, C ⁱ   Herry, A ^j   Luquet, I ^g   Desangles, F ^k   Michaux, L ^l   Verellen Dumoulin, C ^l   Perrot, C ^m   Van den Akker, J ^m   Lespinasse, J ⁿ   Eclache, V ^o   Berger, R ^p   more..

^a HÔPITAL DE HAUTEPIERRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c INSTITUT PAOLI CALMETTES   (France)

^d CHU PURPAN   (France)

^e Laboratory of Cytogenetics   (France)

^f POITIERS UNIVERSITY HOSPITAL   (France)

^g REIMS UNIVERSITY HOSPITAL   (France)

^h HÔPITAL DU BOCAGE   (France)

ⁱ UNIVERSITY HOSPITAL OF TOURS   (France)

^j BREST UNIVERSITY HOSPITAL   (France)

^k University of Paris Descartes   (France)

^l UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^m Section of Radiology   (France)

ⁿ Laboratory of Cytogenetics   (France)

^o Laboratory of Hematology   (France)

^p HÔPITAL NECKER ENFANTS MALADES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BLOOD DISEASE; CHROMOSOME 5; CHROMOSOME 5Q; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; ONCOGENE; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; NEOPLASMS, RADIATION-INDUCED; TRANSLOCATION, GENETIC;

EID: 34250306779     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.01.013     Document Type: Article

References (30)

1. Van den Berghe H., Cassiman J.J., David G., Fryns J.P., Michaux J., and Sokal G. Distinct haematological disorder with deletion of long arm of no. 5 chromosome. Nature 251 (1974) 437-438
2. Rowley J.D., Golomb H.M., and Vardiman J.W. Nonrandom chromosome abnormalities in acute leukemia and dysmyelopoietic syndromes in patients with previously treated malignant disease. Blood 58 (1981) 759-767
3. Sandberg A.A. The chromosomes in human cancer and leukemia. 2nd ed. (1990), Elsevier, New York
4. Groupe Français de Cytogénétique Hématologique. Chromosome analysis of 63 cases of secondary nonlymphoid blood disorders: a cooperative study. Cancer Genet Cytogenet 12 (1984) 95-104
5. Mitelman F., Nilsson P.G., Brandt L., Alimena G., Gastaldi R., and Dallapiccola B. Chromosome pattern, occupation, and clinical features in patients with acute nonlymphocytic leukemia. Cancer Genet Cytogenet 4 (1981) 197-214
6. Rowley J.D. Chromosome abnormalities in human acute nonlymphocytic leukemia: relationship to age, sex, and exposure to mutagens. Natl Cancer Inst Monogr 60 (1982) 17-23
7. Lessard M., Herry A., Berthou C., Léglise M.C., Abgrall J.F., Morice P., and Flandrin G. FISH investigation of 5q and 7q deletions in MDS/AML reveals hidden translocations, insertions and fragmentations of the same chromosomes. Leuk Res 22 (1998) 303-312
8. Bram S., Swolin B., Rodjer S., Stockelberg D., Ogard I., and Back H. Is monosomy 5 an uncommon aberration? Fluorescence in situ hybridization reveals translocations and deletions in myelodysplastic syndromes or acute myelocytic leukemia. Cancer Genet Cytogenet 142 (2003) 107-114
9. Ratain M.J., Kaminer L.S., Bitran J.D., Larson R.A., Le Beau M.M., Skosey C., Purl S., Hoffman P.C., Wade J., and Vardiman J.W. Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung. Blood 70 (1987) 1412-1417
10. Thangavelu M., Bitter M.A., Larson R.A., Davis E.M., Rowley J.D., and Le Beau M.M. der(5)t(5;7)(q11.2;p11.2): a new recurring abnormality in malignant myeloid disorders. Cancer Genet Cytogenet 37 (1989) 1-8
11. ISCN 2005: an international system for human cytogenetic nomenclature (2005). In: Shaffer L.G., and Tommerup N. (Eds) (2005), S. Karger, Basel
12. Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., Sultan C., and French-American-British (FAB) Co-operative Group. Proposals for the classification of the acute leukaemias. Br J Haematol 33 (1976) 451-458
13. Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., and Sultan C. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51 (1982) 189-199
14. In: Jaffe E.S., Harris N.L., Stein H., and Vardiman J.W. (Eds). Pathology and genetics of tumours of haematopoietic and lymphoid tissues. World Health Organization Classification of Tumours (2001), IARC Press, Lyon
15. Lessard M., Herry A., Hélias C., Dastugue N., Brizard F., Radford I., Duchayne E., Brizard A., Berthou C., Abgrall J.F., Morice P., Pris J., and Flandrin G. FISH reveals rearrangements of chromosomes 5 and 7 undetectable using conventional cytogenetic analysis in various in various hematological malignancies. [Abstract]. Blood 90 (1997) 2221
16. Van Limbergen H., Poppe B., Michaux L., Herens C., Brown J., Noens L., Berneman Z., De Bock R., De Paepe A., and Speleman F. Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH. Genes Chromosomes Cancer 33 (2002) 60-72
17. Andersen M.K., Christiansen D.H., and Pedersen-Bjergaard J. Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study. Genes Chromosomes Cancer 42 (2005) 358-371
18. Van den Berghe H., Vermaelen K., Mecucci C., Barbieri D., and Tricot G. The 5q- anomaly. Cancer Genet Cytogenet 17 (1985) 189-255
19. Jaju R.J., Haas O.A., Neat M., Harbott J., Saha V., Boultwood J., Brown J.M., Pirc-Danoewinata H., Krings B.W., Müller U., Morris S.W., Wainscoat J.S., and Kearney L. UK Cancer Cytogenetics Group (UKCCG). A new recurrent translocation, t(5;11)(q35;p15.5), associated with del(5q) in childhood acute myeloid leukemia. Blood 94 (1999) 773-780
20. Berger R., Busson M., Baranger L., Helias C., Lessard M., Dastugue N., and Speleman F. Loss of the NPM1 gene in myeloid disorders with chromosome 5 rearrangements. Leukemia 20 (2006) 319-321
21. Wang P., Spielberger R.T., Thangavelu M., Zhao N., Davis E.M., Iannantuoni K., Larson R.A., and Le Beau M.M. dic(5;17): a recurring abnormality in malignant myeloid disorders associated with mutations of TP53. Genes Chromosomes Cancer 20 (1997) 282-291
22. Christiansen D.H., Andersen M.K., and Pedersen-Bjergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol 19 (2001) 1405-1413
23. Martinez-Ramirez A., Urioste M., Alvarez S., Vizmanos J.L., Calasanz M.J., Cigudosa J.C., and Benitez J. Cytogenetic profile of myelodysplastic syndromes with complex karyotypes: an analysis using spectral karyotyping. Cancer Genet Cytogenet 153 (2004) 39-47
24. Trost D., Hildebrandt B., Beier M., Muller N., Germing U., and Royer-Pokora B. Molecular cytogenetic profiling of complex karyotypes in primary myelodysplastic syndromes and acute myeloid leukemia. Cancer Genet Cytogenet 165 (2006) 51-63
25. Sanderson R.N., Johnson P.R., Moorman A.V., Roman E., Willett E., Taylor P.R., Proctor S.J., Bown N., Ogston S., and Bowen D.T. Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia. Leukemia 20 (2006) 444-450
26. Schoch C., Haferlach T., Bursch S., Gerstner D., Schnittger S., Dugas M., Kern W., Löffler H., and Hiddemann W. Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH. Genes Chromosomes Cancer 35 (2002) 20-29
27. Nisse C., Haguenoer J.M., Grandbastien B., Preudhomme C., Fontaine B., Brillet J.M., Lejeune R., and Fenaux P. Occupational and environmental risk factors of the myelodysplastic syndromes in the North of France. Br J Haematol 112 (2001) 927-935
28. Pedersen-Bjergaard J., Christiansen D.H., Andersen M.K., and Skovby F. Causality of myelodysplasia and acute myeloid leukemia and their genetic abnormalities. Leukemia 16 (2002) 2177-2184
29. Pedersen-Bjergaard J., Christiansen D.H., Desta F., and Andersen M.K. Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 20 (2006) 1943-1949
30. Schoch C., Kern W., Kohlmann A., Hiddemann W., Schnittger S., and Haferlach T. Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile. Genes Chromosomes Cancer 43 (2005) 227-238