Practical synthesis of 4-fluoro-2-(methylthio)benzylamine and the corresponding sulfone and sulfonamide

Synthetic Communications

Volumn 37, Issue 11, 2007, Pages 1887-1897

  Perlow, Debra S ^a   Kuo, Michelle S ^a   Moritz, H Marie ^a   Wai, John S ^a   Egbertson, Melissa S ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Lithiation; Nucleophilic aromatic substitution; Sulfonamide; Sulfone; Thiol

Indexed keywords

2 AMINOMETHYL 5 FLUORO N,N DIMETHYLBENZENESULFONAMIDE; 4 FLUORO 2 METHYLSULFONYLBENZYLAMINE; 4 FLUORO 2 METHYLTHIOBENZYLAMINE; AROMATIC COMPOUND; BENZENESULFONIC ACID DERIVATIVE; BENZONITRILE; BENZYLAMINE; BROMOBENZOIC ACID DERIVATIVE; DIMETHYL DISULFIDE; INTEGRASE INHIBITOR; MESYLIC ACID DERIVATIVE; METHANETHIOL; SOLVENT; SULFONAMIDE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; METALLATION; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 34250303828     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910701319221     Document Type: Article

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