Association with 5′-untranslated region and response to interferon in chronic hepatitis C

Hepato-Gastroenterology

Volumn 54, Issue 75, 2007, Pages 854-857

  Katano, Yoshiaki ^a   Hayashi, Kazuhiko ^a   Ishigami, Masatoshi ^a   Itoh, Akihiro ^a   Hirooka, Yoshiki ^a   Nakano, Isao ^a   Goto, Hidemi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 untranslated region; Chronic hepatitis C; Interferon

Indexed keywords

INTERFERON; ANTIVIRUS AGENT;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HEPATITIS C; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; VIRUS LOAD; ADULT; ANTIBIOTIC RESISTANCE; GENETICS; HEPATITIS C VIRUS; ISOLATION AND PURIFICATION; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE;

5' UNTRANSLATED REGIONS; ADULT; ANTIVIRAL AGENTS; BASE SEQUENCE; DRUG RESISTANCE, VIRAL; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; INTERFERONS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 34250212849     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Seeff LB: Natural history of chronic hepatitis C. Hepatology 2002; 36:S35-46.
2. Di Bisceglie AM, Hoofnagle JH: Optimal therapy of hepatitis C. Hepatology 2002; 36:S121-127.
3. Otagiri H, Fukuda Y, Nakano I, et al: Evaluation of a new assay for hepatitis C virus genotyping and viral load determination in patients with chronic hepatitis C. J Virol Method 2002; 103:137-143.
4. Enomoto N, Sakuma I, Asahina Y, et al: Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 1996; 334:77-81.
5. Nakano I, Fukuda Y, Katano Y, et al: Why is the interferon sensitivity-determining region (ISDR) system useful in Japan? J Hepatol 1999; 30:1014-1022.
6. Yamamoto C, Enomoto N, Kurosaki M, et al: Nucleotide sequence variations in the internal ribosome entry site of hepatitis C virus-1b: no association with efficacy of interferon therapy or serum HCV-RNA levels. Hepatology 1997; 26:1616-1620.
7. Ohno O, Mizokami M, Wu RR, et al: New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J Clin Microbiol 1997; 35:201-207.
8. Chen Z, Weck KE: Hepatitis C virus genotyping: interrogation of the 5′ untranslated region cannot accurately distinguish genotypes 1a and 1b. J Clin Microbiol 2002; 40:3127-3134.
9. Ohno T, Mizokami M, Yamauchi M, et al: Genotype distribution in Nagoya and new genotype (genotype 3a) in Japanese patients with hepatitis C virus. J Gastroenterol 1995; 30:209-214.
10. Poynard T, McHutchison J, Goodman Z, et al: Is an "a la carte" combination interferon alfa-2b plus ribavirin regimen possible for the first line treatment in patients with chronic hepatitis C? The ALGOVIRC Project Group Hepatology. 2000; 31:211-218.
11. Germer JJ, Rys PN, Thorvilson JN, et al: Determination of hepatitis C virus genotype by direct sequence analysis of products generated with the Amplicor HCV test. J Clin Microbiol 1999; 37:2625-2630.
12. Ross RS, Viazov SO, Holtzer CD, et al: Genotyping of hepatitis C virus isolates using CLIP sequencing. J Clin Microbiol 2000; 38:3581-3584.
13. Roque-Afonso AM, Ferey MP, Poveda JD, et al: Performance of TRUGENE trade mark hepatitis C virus 5′ non-coding genotyping kit, a new CLIP trade mark sequencing-based assay for hepatitis C virus genotype determination. J Viral Hepat 2002; 9:385-389.
14. Murakami T, Enomoto N, Kurosaki M, et al: Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection. Hepatology 1999; 30:1045-1053.
15. Kobayashi M, Watanabe K, Ishigami M, et al: Amino acid substitutions in the nonstructural region 5A of hepatitis C virus genotypes 2a and 2b and its relation to viral load and response to interferon. Am J Gastroenterol 2002; 97:988-998.
16. Squadrito G, Orlando ME, Cacciola I, et al: Long-term response to interferon alpha is unrelated to "interferon sensitivity determining region" variability in patients with chronic hepatitis C virus-1b infection. J Hepatol 1999; 30:1023-1027.
17. Paterson M, Laxton CD, Thomas HC, et al: Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response. Gastroenterology 1999; 117:1187-1197.
18. Gerotto M, Dal Pero F, Pontisso P, et al: Two PKR inhibitor HCV proteins correlate with early but not sustained response to interferon. Gastroenterology 2000; 119:1649-1655.
19. Kato J, Kato N, Moriyama M, et al: Interferons specifically suppress the translation from the internal ribosome entry site of hepatitis C virus through a double-stranded RNA-activated protein kinase-independent pathway. J Infect Dis 2002 186:155-163.
20. Manns MP, McHutchison JG, Gordon SC, et al: Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358:958-965.