메뉴 건너뛰기




Volumn 13, Issue 6, 2007, Pages 1936-1946

Combination therapy of an orthotopic renal cell carcinoma model using intratumoral vector-mediated costimulation and systemic interleukin-2

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 15; INTERLEUKIN 2; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; PARVOVIRUS VECTOR;

EID: 34250204525     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-2398     Document Type: Article
Times cited : (21)

References (59)
  • 2
    • 0024247135 scopus 로고
    • Prognostic factors for survival in patients with recurrent or metastatic renal cell carcinoma
    • Elson PJ, Witte RS, Trump DL. Prognostic factors for survival in patients with recurrent or metastatic renal cell carcinoma. Cancer Res 1988;48:7310-3.
    • (1988) Cancer Res , vol.48 , pp. 7310-7313
    • Elson, P.J.1    Witte, R.S.2    Trump, D.L.3
  • 3
    • 0036269257 scopus 로고    scopus 로고
    • Therapeutic options in the management of renal cell carcinoma
    • Glaspy JA. Therapeutic options in the management of renal cell carcinoma. Semin Oncol 2002;29:41-6.
    • (2002) Semin Oncol , vol.29 , pp. 41-46
    • Glaspy, J.A.1
  • 4
    • 0038679329 scopus 로고    scopus 로고
    • Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: An in situ tumor vaccine?
    • Sanchez-Ortiz RF, Tannir N, Ahrar K, Wood CG. Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: an in situ tumor vaccine? J Urol 2003;170:178-9.
    • (2003) J Urol , vol.170 , pp. 178-179
    • Sanchez-Ortiz, R.F.1    Tannir, N.2    Ahrar, K.3    Wood, C.G.4
  • 5
    • 0026730325 scopus 로고
    • Spontaneous regression of histologically proved pulmonary metastases from renal cell carcinoma: A case with 5-year followup
    • Vogelzang NJ, Priest ER, Borden L. Spontaneous regression of histologically proved pulmonary metastases from renal cell carcinoma: a case with 5-year followup. J Urol 1992;148:1247-8.
    • (1992) J Urol , vol.148 , pp. 1247-1248
    • Vogelzang, N.J.1    Priest, E.R.2    Borden, L.3
  • 7
    • 33749451335 scopus 로고    scopus 로고
    • Adjuvant therapy for renal cell carcinoma
    • Jacobsohn KM, Wood CG. Adjuvant therapy for renal cell carcinoma. Semin Oncol 2006;33:576-82.
    • (2006) Semin Oncol , vol.33 , pp. 576-582
    • Jacobsohn, K.M.1    Wood, C.G.2
  • 8
    • 1842633505 scopus 로고    scopus 로고
    • Application of IL-2 and other cytokines in renal cancer
    • McDermott DF, Atkins MB. Application of IL-2 and other cytokines in renal cancer. Expert Opin Biol Ther 2004;4:455-68.
    • (2004) Expert Opin Biol Ther , vol.4 , pp. 455-468
    • McDermott, D.F.1    Atkins, M.B.2
  • 9
    • 33749443423 scopus 로고    scopus 로고
    • Interleukin-2 therapy of metastatic renal cell carcinoma - predictors of response
    • McDermott DF, Atkins MB. Interleukin-2 therapy of metastatic renal cell carcinoma - predictors of response. Semin Oncol 2006;33:583-7.
    • (2006) Semin Oncol , vol.33 , pp. 583-587
    • McDermott, D.F.1    Atkins, M.B.2
  • 10
    • 4644335916 scopus 로고    scopus 로고
    • Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma
    • Atkins MB, Regan M, McDermott D. Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma. Clin Cancer Res 2004;10:6342-6S.
    • (2004) Clin Cancer Res , vol.10
    • Atkins, M.B.1    Regan, M.2    McDermott, D.3
  • 11
    • 0030067276 scopus 로고    scopus 로고
    • Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma
    • Wigginton JM, Komschlies KL, Back TC, et al. Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma. J Natl Cancer Inst 1996;88:38-43.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 38-43
    • Wigginton, J.M.1    Komschlies, K.L.2    Back, T.C.3
  • 13
    • 0028938743 scopus 로고
    • Cellular and molecular studies in the treatment of murine renal cancer
    • Wiltrout RH, Gregorio TA, Fenton RG, et al. Cellular and molecular studies in the treatment of murine renal cancer. Semin Oncol 1995;22:9-16.
    • (1995) Semin Oncol , vol.22 , pp. 9-16
    • Wiltrout, R.H.1    Gregorio, T.A.2    Fenton, R.G.3
  • 14
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • Fyfe G, Fisher RI, Rosenberg SA, et al. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 1995;13:688-96.
    • (1995) J Clin Oncol , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3
  • 15
    • 0028266553 scopus 로고    scopus 로고
    • Rosenberg SA, Yang JC, Topalian SL, et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA1994;271:907-13.
    • Rosenberg SA, Yang JC, Topalian SL, et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA1994;271:907-13.
  • 16
    • 0042914703 scopus 로고    scopus 로고
    • Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    • Yang JC, Sherry RM, Steinberg SM, et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol 2003;21:3127-32.
    • (2003) J Clin Oncol , vol.21 , pp. 3127-3132
    • Yang, J.C.1    Sherry, R.M.2    Steinberg, S.M.3
  • 17
    • 0030942217 scopus 로고    scopus 로고
    • Ultrastructure of streptozotocin-induced renal tumours in mice
    • Delahunt B, Wakefield JS. Ultrastructure of streptozotocin-induced renal tumours in mice. Virchows Arch 1997;430:173-80.
    • (1997) Virchows Arch , vol.430 , pp. 173-180
    • Delahunt, B.1    Wakefield, J.S.2
  • 18
    • 0035881560 scopus 로고    scopus 로고
    • Induction of transplantable mouse renal cell cancers by streptozotocin: In vivo growth, metastases, and angiogenic phenotype
    • Gruys ME, Back TC, Subleski J, et al. Induction of transplantable mouse renal cell cancers by streptozotocin: in vivo growth, metastases, and angiogenic phenotype. Cancer Res 2001;61:6255-63.
    • (2001) Cancer Res , vol.61 , pp. 6255-6263
    • Gruys, M.E.1    Back, T.C.2    Subleski, J.3
  • 19
    • 20144389834 scopus 로고    scopus 로고
    • Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs
    • Frankenberger B, Pohla H, Noessner E, et al. Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs. Clin Cancer Res 2005;11:1733-42.
    • (2005) Clin Cancer Res , vol.11 , pp. 1733-1742
    • Frankenberger, B.1    Pohla, H.2    Noessner, E.3
  • 20
    • 0036223749 scopus 로고    scopus 로고
    • Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma
    • Antonia SJ, Seigne J, Diaz J, et al. Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma. J Urol 2002;167:1995-2000.
    • (2002) J Urol , vol.167 , pp. 1995-2000
    • Antonia, S.J.1    Seigne, J.2    Diaz, J.3
  • 21
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J Immunol 1999;163:5211-8.
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 22
    • 32944472992 scopus 로고    scopus 로고
    • Costimulatory molecules as adjuvants for immunotherapy
    • Hodge JW, Greiner JW, Tsang KY, et al. Costimulatory molecules as adjuvants for immunotherapy. Front Biosci 2006;11:788-803.
    • (2006) Front Biosci , vol.11 , pp. 788-803
    • Hodge, J.W.1    Greiner, J.W.2    Tsang, K.Y.3
  • 23
    • 0033571120 scopus 로고    scopus 로고
    • A triad of costimulatory molecules synergize to amplify T-cell activation
    • Hodge JW, Sabzevari H, Yafal AG, et al. A triad of costimulatory molecules synergize to amplify T-cell activation. Cancer Res 1999;59:5800-7.
    • (1999) Cancer Res , vol.59 , pp. 5800-5807
    • Hodge, J.W.1    Sabzevari, H.2    Yafal, A.G.3
  • 24
    • 4644308143 scopus 로고    scopus 로고
    • + cells by vector-based enhancement of ICAM-1 (CD54) in target cells: Implications for intratumoral vaccine therapy
    • + cells by vector-based enhancement of ICAM-1 (CD54) in target cells: implications for intratumoral vaccine therapy. Cancer Gene Ther 2004;11:665-80.
    • (2004) Cancer Gene Ther , vol.11 , pp. 665-680
    • Slavin-Chiorini, D.C.1    Catalfamo, M.2    Kudo-Saito, C.3
  • 25
    • 18844364432 scopus 로고    scopus 로고
    • The pathway to biomarker discovery: Carbonic anhydrase IX and the prediction of immune responsiveness
    • Panelli MC, Wang E, Marincola FM. The pathway to biomarker discovery: carbonic anhydrase IX and the prediction of immune responsiveness. Clin Cancer Res 2005;11:3601-3.
    • (2005) Clin Cancer Res , vol.11 , pp. 3601-3603
    • Panelli, M.C.1    Wang, E.2    Marincola, F.M.3
  • 26
    • 8744315211 scopus 로고    scopus 로고
    • Antigenic targets for renal cell carcinoma immunotherapy
    • Vieweg J, Jackson A. Antigenic targets for renal cell carcinoma immunotherapy. Expert Opin Biol Ther 2004;4:1791-801.
    • (2004) Expert Opin Biol Ther , vol.4 , pp. 1791-1801
    • Vieweg, J.1    Jackson, A.2
  • 27
    • 33745501867 scopus 로고    scopus 로고
    • Manipulating the local tumor microenvironment with poxviruses expressing costimulatory molecules
    • Kaufman HL. Manipulating the local tumor microenvironment with poxviruses expressing costimulatory molecules. Ann N Y Acad Sci 2005;1062:41-50.
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 41-50
    • Kaufman, H.L.1
  • 28
    • 0035132541 scopus 로고    scopus 로고
    • Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant
    • Kass E, Panicali DL, Mazzara G, Schlom J, Greiner JW. Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant. Cancer Res 2001;61:206-14.
    • (2001) Cancer Res , vol.61 , pp. 206-214
    • Kass, E.1    Panicali, D.L.2    Mazzara, G.3    Schlom, J.4    Greiner, J.W.5
  • 29
    • 0029884292 scopus 로고    scopus 로고
    • Improved immunotherapy of a recombinant carcinoembryonic antigen vaccinia vaccine when given in combination with interleukin-2
    • McLaughlin JP, Schlom J, Kantor JA, Greiner JW. Improved immunotherapy of a recombinant carcinoembryonic antigen vaccinia vaccine when given in combination with interleukin-2. Cancer Res 1996;56:2361-7.
    • (1996) Cancer Res , vol.56 , pp. 2361-2367
    • McLaughlin, J.P.1    Schlom, J.2    Kantor, J.A.3    Greiner, J.W.4
  • 30
    • 0037728812 scopus 로고    scopus 로고
    • The cytotoxic T-lymphocyte response against a poorly immunogenic mammary adenocarcinoma is focused on a single immunodominant class I epitope derived from the gp70 Env product of an endogenous retrovirus
    • Rosato A, Santa SD, Zoso A, et al. The cytotoxic T-lymphocyte response against a poorly immunogenic mammary adenocarcinoma is focused on a single immunodominant class I epitope derived from the gp70 Env product of an endogenous retrovirus. Cancer Res 2003;63:2158-63.
    • (2003) Cancer Res , vol.63 , pp. 2158-2163
    • Rosato, A.1    Santa, S.D.2    Zoso, A.3
  • 31
    • 0033910714 scopus 로고    scopus 로고
    • Comparative studies of the effects of recombinant GM-CSF and GM-CSF administered via a poxvirus to enhance the concentration of antigen-presenting cells in regional lymph nodes
    • Kass E, Parker J, Schlom J, Greiner JW. Comparative studies of the effects of recombinant GM-CSF and GM-CSF administered via a poxvirus to enhance the concentration of antigen-presenting cells in regional lymph nodes. Cytokine 2000;12:960-71.
    • (2000) Cytokine , vol.12 , pp. 960-971
    • Kass, E.1    Parker, J.2    Schlom, J.3    Greiner, J.W.4
  • 32
    • 9544221745 scopus 로고    scopus 로고
    • The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product
    • Huang AY, Gulden PH, Woods AS, et al. The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proc Natl Acad Sci U S A 1996;93:9730-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9730-9735
    • Huang, A.Y.1    Gulden, P.H.2    Woods, A.S.3
  • 33
    • 33746547247 scopus 로고    scopus 로고
    • The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
    • Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006;6:595-601.
    • (2006) Nat Rev Immunol , vol.6 , pp. 595-601
    • Waldmann, T.A.1
  • 35
    • 0035102242 scopus 로고    scopus 로고
    • Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
    • Waldmann TA, Dubois S, Tagaya Y. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 2001;14:105-10.
    • (2001) Immunity , vol.14 , pp. 105-110
    • Waldmann, T.A.1    Dubois, S.2    Tagaya, Y.3
  • 36
    • 20044364936 scopus 로고    scopus 로고
    • Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
    • Marshall JL, Gulley JL, Arlen PM, et al. Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J Clin Oncol 2005;23:720-31.
    • (2005) J Clin Oncol , vol.23 , pp. 720-731
    • Marshall, J.L.1    Gulley, J.L.2    Arlen, P.M.3
  • 37
    • 34250729323 scopus 로고    scopus 로고
    • A pilot study of a PANVAC-V and PANVAC-F in patients (pts) with metastatic carcinoma [abstract]
    • Gulley J, Arlen P, Dahut W. A pilot study of a PANVAC-V and PANVAC-F in patients (pts) with metastatic carcinoma [abstract]. Proc Am Soc Clin Oncol 2006.
    • (2006) Proc Am Soc Clin Oncol
    • Gulley, J.1    Arlen, P.2    Dahut, W.3
  • 38
    • 33746004926 scopus 로고    scopus 로고
    • A phase 1 study of sequential vaccinations with recombinant fowlpox-PSA (L155)-TRICOM (rF) alone, or in combination with recombinant vaccinia-PSA (L155) (rV); and the role of GM-CSF in patients (pts) with prostate cancer
    • Arlen P, Gulley J, Dahut W. A phase 1 study of sequential vaccinations with recombinant fowlpox-PSA (L155)-TRICOM (rF) alone, or in combination with recombinant vaccinia-PSA (L155) (rV); and the role of GM-CSF in patients (pts) with prostate cancer. Proc Am Soc Clin Oncol 2004;23:2522a.
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Arlen, P.1    Gulley, J.2    Dahut, W.3
  • 39
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E,Lazenby A, etal. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A 1993;90:3539-43.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 40
    • 0030944023 scopus 로고    scopus 로고
    • Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer
    • Simons JW, Jaffee EM, Weber CE, et al. Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res 1997;57:1537-46.
    • (1997) Cancer Res , vol.57 , pp. 1537-1546
    • Simons, J.W.1    Jaffee, E.M.2    Weber, C.E.3
  • 41
    • 0035360260 scopus 로고    scopus 로고
    • Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects
    • Grosenbach DW, Barrientos JC, Schlom J, Hodge JW. Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects. Cancer Res 2001;61:4497-505.
    • (2001) Cancer Res , vol.61 , pp. 4497-4505
    • Grosenbach, D.W.1    Barrientos, J.C.2    Schlom, J.3    Hodge, J.W.4
  • 42
    • 0037108688 scopus 로고    scopus 로고
    • Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self-antigen and antitumor activity
    • Aarts WM, Schlom J, Hodge JW. Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self-antigen and antitumor activity. Cancer Res 2002;62:5770-7.
    • (2002) Cancer Res , vol.62 , pp. 5770-5777
    • Aarts, W.M.1    Schlom, J.2    Hodge, J.W.3
  • 43
    • 1042278718 scopus 로고    scopus 로고
    • Intratumoral vaccination and diversified subcutaneous/intratumoral vaccination with recombinant poxviruses encoding a tumor antigen and multiple costimulatory molecules
    • Kudo-Saito C, Schlom J, Hodge JW. Intratumoral vaccination and diversified subcutaneous/intratumoral vaccination with recombinant poxviruses encoding a tumor antigen and multiple costimulatory molecules. Clin Cancer Res 2004;10:1090-9.
    • (2004) Clin Cancer Res , vol.10 , pp. 1090-1099
    • Kudo-Saito, C.1    Schlom, J.2    Hodge, J.W.3
  • 44
    • 27344449925 scopus 로고    scopus 로고
    • T cell avidity and tumor recognition: Implications and therapeutic strategies
    • McKee MD, Roszkowski JJ, Nishimura MI. T cell avidity and tumor recognition: implications and therapeutic strategies. J Transl Med 2005;3:35.
    • (2005) J Transl Med , vol.3 , pp. 35
    • McKee, M.D.1    Roszkowski, J.J.2    Nishimura, M.I.3
  • 45
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller MA, Leggatt GR, Berzofsky JA. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A 1996;93:4102-7.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4102-4107
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 48
    • 28544452409 scopus 로고    scopus 로고
    • Combination B7-Fc fusion protein treatment and Treg cell depletion therapy
    • Liu A, Hu P, Khawli LA, Epstein AL. Combination B7-Fc fusion protein treatment and Treg cell depletion therapy. Clin Cancer Res 2005;11:8492-502.
    • (2005) Clin Cancer Res , vol.11 , pp. 8492-8502
    • Liu, A.1    Hu, P.2    Khawli, L.A.3    Epstein, A.L.4
  • 49
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull J, Su Z, Rizzieri D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 2005;115:3623-33.
    • (2005) J Clin Invest , vol.115 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3
  • 50
    • 16844362403 scopus 로고    scopus 로고
    • Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses
    • Kudo-Saito C, Schlom J, Hodge JW. Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses. Clin Cancer Res 2005;11:2416-26.
    • (2005) Clin Cancer Res , vol.11 , pp. 2416-2426
    • Kudo-Saito, C.1    Schlom, J.2    Hodge, J.W.3
  • 51
    • 33846621955 scopus 로고    scopus 로고
    • Small molecule tyrosine kinase inhibitors in the treatment of solid tumors: An update of recent developments
    • Steeghs N, Nortier JW, Gelderblom H. Small molecule tyrosine kinase inhibitors in the treatment of solid tumors: an update of recent developments. Ann Surg Oncol 2007;14:942-53.
    • (2007) Ann Surg Oncol , vol.14 , pp. 942-953
    • Steeghs, N.1    Nortier, J.W.2    Gelderblom, H.3
  • 54
    • 33748614966 scopus 로고    scopus 로고
    • Randomized phase II trial of sorafenib in advanced renal cell carcinoma (RCC): Impact of crossover on survival
    • Eisen T, Bukowski R, Staehler M, et al. Randomized phase II trial of sorafenib in advanced renal cell carcinoma (RCC): impact of crossover on survival. Am Soc Clin Oncol Annu Meet 2006. p. 24.
    • (2006) Am Soc Clin Oncol Annu Meet , pp. 24
    • Eisen, T.1    Bukowski, R.2    Staehler, M.3
  • 55
    • 33744805087 scopus 로고    scopus 로고
    • Effects of different combinations of gefitinib and irinotecan in lung cancer cell lines expressing wild or deletional EGFR
    • Shimoyama T, Koizumi F, Fukumoto H, et al. Effects of different combinations of gefitinib and irinotecan in lung cancer cell lines expressing wild or deletional EGFR. Lung Cancer 2006;53:13-21.
    • (2006) Lung Cancer , vol.53 , pp. 13-21
    • Shimoyama, T.1    Koizumi, F.2    Fukumoto, H.3
  • 56
    • 32144441841 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells
    • Pu YS, Hsieh MW, Wang CW, et al. Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells. Biochem Pharmacol 2006;71:751-60.
    • (2006) Biochem Pharmacol , vol.71 , pp. 751-760
    • Pu, Y.S.1    Hsieh, M.W.2    Wang, C.W.3
  • 57
    • 33645873928 scopus 로고    scopus 로고
    • Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro
    • Taira N, Doihara H, Oota T, et al. Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro. Acta Med Okayama 2006;60:25-34.
    • (2006) Acta Med Okayama , vol.60 , pp. 25-34
    • Taira, N.1    Doihara, H.2    Oota, T.3
  • 58
    • 31544464043 scopus 로고    scopus 로고
    • Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma
    • Chun PY, Feng FY, Scheurer AM, et al. Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma. Cancer Res 2006;66:981-8.
    • (2006) Cancer Res , vol.66 , pp. 981-988
    • Chun, P.Y.1    Feng, F.Y.2    Scheurer, A.M.3
  • 59
    • 11244255868 scopus 로고    scopus 로고
    • Kobayashi H, Dubois S, Sato N, et al. Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance. Blood 2005;105:721-7.
    • Kobayashi H, Dubois S, Sato N, et al. Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance. Blood 2005;105:721-7.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.