Degenerative and apoptotic events at retinal and optic nerve level after experimental induction of ocular hypertension

Molecular and Cellular Biochemistry

Volumn 301, Issue 1-2, 2007, Pages 155-163

  Calandrella, Nicola ^a   Scarsella, Gianfranco ^a   Pescosolido, Nicola ^a   Risuleo, Gianfranco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Apoptosis; Experimental hypertension; Glaucoma; Optic nerve; Retina

Indexed keywords

CASPASE 3; DNA FRAGMENT; GLIAL FIBRILLARY ACIDIC PROTEIN; METHYLCELLULOSE; PEROXIDE; TROLOX C; UBIQUITIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; APOPTOSIS; ARTICLE; ASTROCYTE; BLINDNESS; CELL DEATH; CELL DEGENERATION; CELL STRESS; CHROMATIN; CONTROLLED STUDY; DISEASE SEVERITY; GLAUCOMA; IMMUNOLOCALIZATION; INOCULATION; INTRAOCULAR HYPERTENSION; MALE; NICK END LABELING; NONHUMAN; NUCLEOSOME; OPTIC NERVE; OXIDATIVE STRESS; PROTEIN DEGRADATION; RAT; RETINA GANGLION CELL; SYMPTOM; VISUAL IMPAIRMENT;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CHROMATIN; DNA FRAGMENTATION; GLAUCOMA; HUMANS; IN SITU NICK-END LABELING; INTRAOCULAR PRESSURE; MALE; OCULAR HYPERTENSION; OPTIC NERVE; RATS; RATS, WISTAR; RETINA; RETINAL DEGENERATION;

EID: 34250202543     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9407-0     Document Type: Article

References (46)

1. Quigley HA (1987) Reappraisal of the mechanism of glaucomatous optic nerve damage. Eye 1:318-322
2. De Gregorio F, Pecori-Giraldi J, De Stefano C, Virno M (1997) Correlation between ocular hypertension induced by ibopamine and perimetric defect in primary open angle glaucoma. Eur J Ophthalmol 7:152-155
3. Friedman DS, Wilson MR, Liebmann JM, Fechtner RD, Weinreb RN (2004) An evidence based assessment of risk factors for the progression of ocular hypertension and glaucoma. Am J Ophthalmol Rev 138:19-31
4. Quigley HA, Enger C, Katz J, Sommer A, Scott R, Gilbert D (1994) Risk factors for the development of glaucomatous visual field loss in ocular hypertension. Arch Ophthalmol 112:644-649
5. Quigley HA, McKinnon SJ, Zack DJ, Pease ME, Kerrigan-Baumrind LA, Kerrigan FD, Mitchell RS (2000) Retrograde axonal trasport of BDNF in retinal ganglion cell is blocked by acute IOP elevation in rat. Invest Ophthalmol Vis Sci 41:3460-3466
6. Sommers A, Tielsh JM, Katz J (1991) Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. Arch Ophthalmol 109:1090-1095
7. Wax MB, Tezel G, Kobayashi S, Hernandez MR (2000) Responses of different cells lines from ocular tissues to elevated hydrostatic pressure. Br J Ophthalmol 84:423-428
8. Eddleston M, Mucke L (1993) Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 54:15-36
9. Barnett NL, Pow DV, Bull ND (2001) Differential perturbation of neuronal and glial glutamate transport system in retinal ischemia. Neurochem Int 39:291-299
10. McKinnon SJ (1997) Glaucoma, apoptosis and neuroprotection. Curr Opin Ophthalmol 8:28-37
11. Quigley HA, Nickells RW, Kerrigan LA, Pease ME, Thibault DJ, Zack DJ (1995) Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci 36:374-386
12. Noremberg MD (1994) Astrocyte responses to CNS injury. J Neuropatol Exp Neurol 3:213-220
13. Hernandez MR, Pena JD (1997) The optic nerve head in glaucomatous optic neuropathy. Arch Ophthalmol 115:389-395
14. Ye H, Hernandez MR (1995) Heterogeneity of astrocytes in human optic nerve head. J Comp Neurol 4:441-452
15. Ricard CS, Kobayashi S, Pena JDO, Salvador-Silva M, Agapova O, Hernandez MR (2000) Selective expression of neuronal cell adhesion molecule (NCAM)-180 in optic nerve head astrocytes exposed to elevated hydrostatic pressure in vitro. Mol Brain Res 81:62-79
16. Varela HJ, Hernandez MR (1997) Astrocyte responses in human optic nerve head with primary open angle glaucoma. Journal of glaucoma 6:303-313
17. Lieth E, Barber AJ, Xu B (1998) Glial reactivity and impaired glutamate metabolism in short term experimantal diabetic retinopathy. Diabetes 47:815-820
18. Mizutani M, Gerhardinger C, Lorenzi M (1998) Müller cell changes in human diabetic retinophahaty. Diabetes 47:445-449
19. Erickson PA, Fisher SK, Guerin CJ, Anderson DH, Kaska DD (1987) Glial fibrillary acidic protein increases in Müller cells after retinal detachment. Exp Eye Res 44:37-48
20. Guidry C, Medeiros NE, Curcio CA (2002) Phenotypic variation of retinal pigment epithelium in age-related macular degeneration. Invest Ophthalmol Vis Sci 43:266-273
21. Tanihara H, Hangai M, Sawaguchi S, Abe H, Kageyama M, Nakazawa F, Shirasawa E, Honda Y (1997) Up-regulation of glial fibrillary acidic protein in the retina of primate eyes with experimental glaucoma. Arch Ophthalmol 115:752-756
22. Wang X, Tay SSW, Ng YK (2000) An immunohistochemical study of neuronal and glial cell reaction in retina of rats with experimental glaucoma. Exp Brain Res 132:476-484
23. Wang L, Cioffi A, Dong J, Fortune B (2002) Immunohistologic evidence for retinal glial cell changes in human glaucoma. Invest Ophthalmol Vis Sci 43:1088-1094
24. Yuan L, Neufeld AH (2000) Tumor necrosis factor-alpha: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head. Glia 32:42-50
25. Bonfoco E, Kranic D, Ankarcrona M, Nicotera P, Lipton SA (1995) Apoptosis and necrosis: Two distinct event induced respective by mild and intense insult with NMDA or nitric oxide/superosside in cortical cell cultures. Proc Natl Acad Sci 92:7162-7166
26. Cotinet A, Goureau O, Hicks D (1997) Tumor necrosis factor and nitric oxide production by Retinal Müller glial cell from rats exhibiting inherited retinal dystrophy. Glia 1:59-69
27. Dugan LL, Sensi SL, Canzoniero LM (1995) Mithocondrial production of reactive oxygen species in cortical neurons after exposure to N-methyl-D-aspartate. J Neurosci 10:6377-6388
28. Neufeld AH (1999) Nitric oxide: A potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol 43:129-135
29. Raivich G, Bohatschek M, Kloss CUA, Werner A, Jones LL, Kreutzberg WG. (1999) Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanism and cues to physiological function. Brain Res Rev 30:77-105
30. Tezel G, Wax MB (2000) Increased production of tumor necrosis factor by glial cells exposed to simulate ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells. J Neurosci 23:8693-8700
31. Salvador-Silva M, Ricard CS, Agapova OA, Yang P, Hernandez MR (2001) Expression of small heat shock protein and intermediate filaments in the human optic nerve head astrocytes exposed to elevated hydrostatic pressure in vitro. J Neurosci Res 66:59-73
32. Hernandez MR (2000) The optic nerve head in glaucoma: Role of astrocytes in tissue remodeling. Prog Retin Eye Res 3:297-321
33. Tezel G, Hernandez MR, Wax MB (2001) In vitro evaluation of reactive astrocyte migration, a component of tissue component remodeling in glaucomatous optic nerve head. Glia 3:178-189
34. Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD (2000) Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288:874-877
35. Bresin A, Iacoangeli A, Risuleo G, Scarsella G (2001) Ubiquitin depend proteolysis is activated in apoptotic fibroblasts in culture. Mol Cell Biochem 220:57-60
36. Naash MI, Al-Ubaidi MR, Andreson RE (1997) Light exposure induces ubiquitin conjugation and degradation activities in the rat retina. Invest Ophthalmol Vis Sci 38:2344-2354
37. Lee JC, Peter ME (2003) Regulation of apoptosis by ubiquitination. Immunol Rev 193:39-47
38. Risuleo G, Cristofanilli M, Scarsella G (2003) Acute ischemia/hypoxia in rat hippocampal neurons activates nuclear ubiquitinand alters both chromatin and DNA. Mol Cell Biochem 250:73-80
39. Ben-Shlomo G, Bakalash S, Lambrou GN, Latour E, Dawson WW, Schwartz M, Ofri R (2005) Pattern electroretinography in a rat model of ocular hypertension: Functional evidence for early detection of inner retinal damage. Exp Eye Res 81:340-349
40. Kanamori A, Nakamura M, Nakanishi Y, Yamada Y, Negi A (2005) Long-term glial reactivity in rat retinas ipsilateral and contralateral to experimental glaucoma. Exp Eye Res 81:48-56
41. Moreno MC, Aldana Marcos HJ, Croxatto O, Sande PH, Campanelli J, Jaliffa CO, Benozzi J, Rosenstein RE (2005) A new experimental model of glaucoma in rats through intracameral injections of hyaluronic acid. Exp Eye Res 81:71-80
42. McClain DE, Kalinich JF, Ramakrishnan N (1995) Trolox inhibits apoptosis in irradiated MOLT-4 lymphocytes. FASEB J 9:1345-1354
43. Zhu MD, Cai FY (1992) Development of experimental chronic intraocular hypertension in the rabbit. Austl Nw Z J Ophthalmol 20:225-234
44. Drize JH, Woodard G, Calvery HO (1944) Methods for the study of irritation and toxicity ofsubstances applied topically to the skin and mucous membranes. J Pharm Exp Ther 82:377-390
45. Savada A, Neufeld AH (1999) Confirmation of the model of chronic, moderately elevated intraocular pressure. Exp Eye Res 69:525-531
46. Jesenberger V, Jentsch S (2002) Deadly encounter: Ubiquitin meets apoptosis. Nat Rev Mol Cell Biol. 3:112-121