Quantifying fixation in patients with Stargardt disease

Vision Research

Volumn 47, Issue 15, 2007, Pages 2076-2085

  Reinhard, Jens ^a   Messias, André ^a   Dietz, Klaus ^b   MacKeben, Manfred ^c   Lakmann, Raimund ^a   Scholl, Hendrik P N ^a,d   Apfelstedt Sylla, Eckart ^a,e   Weber, Bernhard H F ^f   Seeliger, Mathias W ^a   Zrenner, Eberhart ^a   Trauzettel Klosinski, Susanne ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c SMITH KETTLEWELL EYE RESEARCH INSTITUTE   (United States)

^d UNIVERSITY HOSPITAL BONN   (Germany)

^e KATHARINENHOSPITAL   (Germany)

^f UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Fixation stability; Maculopathy; Preferred retinal locus (PRL); Scanning Laser Ophthalmoscope (SLO); Stargardt disease

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DYNAMICS; EYE FIXATION; FEMALE; GENETIC ANALYSIS; HUMAN; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING LASER OPHTHALMOSCOPE; STARGARDT DISEASE; VISUAL ACUITY;

ADOLESCENT; ADULT; ATP-BINDING CASSETTE TRANSPORTERS; EYE MOVEMENTS; FEMALE; FIXATION, OCULAR; FOVEA CENTRALIS; HUMANS; MALE; MIDDLE AGED; MUTATION; OPHTHALMOSCOPY; OPTIC DISK; RETINAL DEGENERATION; VISUAL ACUITY;

EID: 34250201469     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2007.04.012     Document Type: Article

References (33)

1. Allikmets R., Singh N., Sun H., Shroyer N.F., Hutchinson A., Chidambaram A., et al. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nature Genetics 15 (1997) 236-246
2. Altpeter E., Mackeben M., and Trauzettel-Klosinski S. The importance of sustained attention for patients with maculopathies. Vision Research 40 (2000) 1539-1547
3. Bellmann C., Feely M., Crossland M.D., Kabanarou S.A., and Rubin G.S. Fixation stability using central and pericentral fixation targets in patients with age-related macular degeneration. Ophthalmology 111 (2004) 2265-2270
4. Crossland M.D., Culham L.E., Kabanarou S.A., and Rubin G.S. Preferred retinal locus development in patients with macular disease. Ophthalmology 112 (2005) 1579-1585
5. Crossland M.D., Sims M., Galbraith R.F., and Rubin G.S. Evaluation of a new quantitative technique to assess the number and extent of preferred retinal loci in macular disease. Vision Research 44 (2004) 1537-1546
6. Crossland M.D., Culham L.E., and Rubin G.S. Fixation stability and reading speed in patients with newly developed macular disease. Ophthalmic and Physiological Optics 24 (2004) 327-333
7. Crossland M.D., and Rubin G.S. The use of an infrared eyetracker to measure fixation stability. Optometry and Vision Science 79 (2002) 735-739
8. Duret F., Issenhuth M., and Safran A.B. Combined use of several preferred retinal loci in patients with macular disorders when reading single words. Vision Research 39 (1999) 873-879
9. Dvoretzky A., and Erdös P. Some problems on random walk in space. In: Neyman J. (Ed). Proceedings of the second Berkeley symposium on mathematical statistics and probability (1950), University of California Press, Berkeley 353-367
10. Fletcher D.C., and Schuchard R.A. Preferred retinal loci relationship to macular scotomas in a low-vision population. Ophthalmology 104 (1997) 632-638
11. Fletcher D.C., Schuchard R.A., and Watson G. Relative locations of macular scotomas near the PRL: effect on low vision reading. Journal of Rehabilitation Research and Development 36 (1999) 356-364
12. Guez J.E., Le Gargasson J.F., Rigaudière F., and O'Regan J.K. Is there a systematic location for the pseudo-fovea in patients with central scotoma?. Vision Research 33 (1993) 1271-1279
13. Liu W., Smith D.I., Rechtzigel K.J., Thibodeau S.N., and James C.D. Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations. Nucleic Acids Research 26 (1998) 1396-1400
14. MacKeben M., and Gofen A. Gaze-contingent display for retinal function testing by scanning laser ophthalmoscope. Journal of the Optical Society of America A 24 (2007) 1402-1410 (feature issue on "Retinal Imaging")
15. Messias, A. M., Reinhard, J., Cruz, A. A., Dietz, K., & Trauzettel-Klosinski, S. (submitted for publication). Eccentric fixation in Stargardt's disease assessed by Tübingen Perimetry. Investigative Ophthalmology and Visual Science.
16. Møller F., Laursen M.L., and Sjølie A.K. The contribution of microsaccades and drifts in the maintenance of binocular steady fixation. Graefe's Archive for Clinical and Experimental Ophthalmology 244 (2006) 465-471
17. Nachmias J. Two-dimensional motion of the retinal image during monocular fixation. Journal of the Optical Society of America 49 (1959) 901-908
18. Nachmias J. Determiners of the drift of the eye during monocular fixation. Journal of the Optical Society of America 51 (1961) 761-766
19. Rivera A., White K., Stöhr H., Steiner K., Hemmrich N., Grimm T., et al. A comprehensive survey of sequence variation in the ABCA4 (ABCR) gene in Stargardt disease and age-related macular degeneration. American Journal of Human Genetics 67 (2000) 800-813
20. Rohrschneider K. Determination of the location of the fovea on the fundus. Investigative Ophthalmology and Visual Science 45 (2004) 3257-3258
21. Rohrschneider K., Glück R., Blankenagel A., and Völcker H.E. Fixationsverhalten bei Morbus Stargardt. Ophthalmologe 94 (1997) 624-628
22. Sansbury R.V., Skavenski A.A., Haddad G.M., and Steinman R.M. Normal fixation of eccentric targets. Journal of the Optical Society of America 63 (1973) 612-614
23. Stargardt K. Über familiäre, progressive Degeneration in der Maculagegend des Auges. Graefe's Archive for Clinical and Experimental Ophthalmology 71 (1909) 534-550
24. Steinman R.M. Effect of target size, luminance, and color on monocular fixation. Journal of the Optical Society of America 55 (1965) 1158-1165
25. Steinman R.M., Haddad G.M., Skavenski A.A., and Wyman D. Miniature eye movement. Science 181 (1973) 810-819
26. Sunness J.S., Applegate C.A., Haselwood D., and Rubin G.S. Fixation patterns and reading rates in eyes with central scotomas from advanced atrophic age-related macular degeneration and Stargardt disease. Ophthalmology 103 (1996) 1458-1466
27. Timberlake G.T., Sharma M.K., Grose S.A., Gobert D.V., Gauch J.M., and Maino J.H. Retinal location of the preferred retinal locus relative to the fovea in scanning laser ophthalmoscope images. Optometry and Vision Science 82 (2005) E177
28. Timberlake G.T., Peli E., Essock E.A., and Augliere R.A. Reading with a macular scotoma. II. Retinal locus for scanning text. Investigative Ophthalmology and Visual Science 28 (1987) 1268-1274
29. Timberlake G.T., Mainster M.A., Peli E., Augliere R.A., Essock E.A., and Arend L.E. Reading with a macular scotoma. I. Retinal location of scotoma and fixation area. Investigative Ophthalmology and Visual Science 27 (1986) 1137-1147
30. Trauzettel-Klosinski S., and Tornow R.P. Fixation behavior and reading ability in macular scotoma-Assessed by Tübingen manual perimetry and Scanning laser ophthalmoscopy. Neuro-ophthalmology 16 (1996) 241-253
31. Von Noorden G., and Mackensen G. Phenomenology of eccentric fixation. American Journal of Ophthalmology 53 (1962) 642-660
32. Whittaker S.G., Budd J., and Cummings R.W. Eccentric fixation with macular scotoma. Investigative Ophthalmology and Visual Science 29 (1988) 268-278
33. Xu Z., Schuchard R., Ross D., and Benkeser P. Tracking retinal motion with a scanning laser ophthalmoscope. Journal of Rehabilitation Research and Development 42 (2005) 373-380