Enantioselective synthesis of 3,3-disubstituted piperidine derivatives by enolate dialkylation of phenylglycinol-derived oxazolopiperidone lactams

Journal of Organic Chemistry

Volumn 72, Issue 12, 2007, Pages 4431-4439

  Amat, Mercedes ^a   Lozano, Oscar ^a   Escolano, Carmen ^a   Molins, Elies ^b   Bosch, Joan ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOIDS; LACTAM; SUBSTITUENTS;

DERIVATIVES; ENANTIOSELECTIVITY; STEREOSELECTIVITY; STOICHIOMETRY;

ORGANIC COMPOUNDS;

1 (TERT BUTOXYCARBONYL) 3 ETHYL 3 (HYDROXYETHYL)PIPERIDINE; 3 ALLYL 3 ETHYL 1 [2 HYDROXY 1 PHENYLETHYL] 2 PIPERIDONE; 3 ALLYL 3 ETHYL 2 PIPERIDONE; 3 BENZYL 3 ETHYL 1 [2 HYDROXY 1 PHENYLETHYL] 2 PIPERIDONE; 3 BENZYL 3 ETHYL 2 PIPERIDONE; 3 ETHYL 1 (3 INDOLYLACETYL)PIPERIDINE 3 ACETIC ACID; 3 ETHYL 2 (2 HYDROXYETHYL) 1 [2 HYDROXY 1 PHENYL ETHYL]PIPERIDINE; 6 ALLYL 6 ETHYL 5 OXO 3 PHENYL 2,3,6,7,8 8A HEXAHYDRO 5H OXAZOLO[3,2 A]PYRIDINE; 6 BENZYL 6 ETHYL 5 OXO 3 PHENYL 2,3,6,7,8 8A HEXAHYDRO 5H OXAZOLO[3,2 A]PYRIDINE; 6 ETHYL 5 OXO 3 PHENYL 2,3,6,7,8A HEXAHYDRO 5H OXAZOLO[3,2 A]PYRIDINE 6 ACETIC ACID; ACETIC ACID DERIVATIVE; ALKALOID; ALKENE; ALKENE DERIVATIVE; ASPIDOSPERMIDINE; BENZENE DERIVATIVE; ENOLATE; GLYCINE; LACTAM DERIVATIVE; METHYL 3 ETHYL 1 (3 INDOLYLACETYL)PIPERIDINE 3 ACETATE; METHYL 3 ETHYL PIPERIDINEACETATE; METHYL 3 ETHYLPIPERIDINE 3 ACETATE; OXAZOLOPIPERIDONE; OXAZOLOPIPERIDONE LACTAM DERIVATIVE; PHENYLGLYCINOL; PIPERIDINE DERIVATIVE; PIPERIDONE DERIVATIVE; QUEBRACHAMINE; RHAZINILAM; UNCLASSIFIED DRUG; VINBURNINE;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENANTIOSELECTIVITY; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALKYLATION; GLYCINE; INDOLE ALKALOIDS; LACTAMS; OXAZOLES; PIPERIDINES; PIPERIDONES; STEREOISOMERISM;

EID: 34250195722     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo070397q     Document Type: Article

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