Tandem α-Cyano Enamine/Enolate Alkylations on Bicyclic Lactams: Asymmetric Carbocycle and Heterocycle Synthesis

Journal of Organic Chemistry

Volumn 63, Issue 5, 1998, Pages 1619-1629

  Schwarz, Jacob B ^a   Meyers, A I ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001148880     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971920b     Document Type: Article

References (21)

1. Schwarz, J. B.; Meyers, A. I. Tetrahedron 1997, 53, 8795.
2. For reviews of the chemistry of bicyclic lactams, see: Romo, D.; Meyers, A. I. Tetrahedron 1991, 47, 9503. Meyers, A. I.; Brengel, G. P. J. Chem. Soc., Chem. Commun. 1997, 1.
3. For reviews of the chemistry of bicyclic lactams, see: Romo, D.; Meyers, A. I. Tetrahedron 1991, 47, 9503. Meyers, A. I.; Brengel, G. P. J. Chem. Soc., Chem. Commun. 1997, 1.
4. (a) Meyers, A. I.; Fleming, S. A. J. Am. Chem. Soc. 1986, 108, 306.
5. (b) Meyers, A. I.; Tschantz, M. A.; Brengel, G. P. J. Org. Chem. 1995, 60, 4359.
6. Brengel, G. P.; Rithner, C.; Meyers, A. I. J. Org. Chem. 1994, 59, 5144.
7. Meyers, A. I.; Bienz, S.; Kwon, H.-B.; Wallace, R. H. Helv. Chim. Acta 1996, 79, 1026.
8. Meyers, A. I.; Busacca, C. A. J. Chem. Soc., Perkin Trans. 1 1991, 2299.
9. Reinecke, M. G.; Kray, L. R.; Francis, R. F. J. Org. Chem. 1972, 37, 3489.
10. Snyder, L.; Meyers, A. I. J. Org. Chem. 1993, 58, 7507. Meyers, A. I.; Flisak, J. R.; Aitken, R. A. J. Am. Chem. Soc. 1987, 109, 5446. Castro, B. R. Org. React. 1983, 29, 1.
11. Snyder, L.; Meyers, A. I. J. Org. Chem. 1993, 58, 7507. Meyers, A. I.; Flisak, J. R.; Aitken, R. A. J. Am. Chem. Soc. 1987, 109, 5446. Castro, B. R. Org. React. 1983, 29, 1.
12. Snyder, L.; Meyers, A. I. J. Org. Chem. 1993, 58, 7507. Meyers, A. I.; Flisak, J. R.; Aitken, R. A. J. Am. Chem. Soc. 1987, 109, 5446. Castro, B. R. Org. React. 1983, 29, 1.
13. Meyers, A. I.; Lefker, B. A.; Wanner, K. T.; Aitken, R. A. J. Org. Chem. 1986, 51, 1936.
14. Eliel, E. L.; Wilen, S. H. Stereochemistry of Organic Compounds; John Wiley and Sons, Inc: New York, 1994.
15. Devine, P. N.; Meyers, A. I. J. Am. Chem. Soc. 1994, 116, 2633.
16. Woodward, R. B.; Sondheimer, F.; Taub, D.; Heusler, K.; McLamore, W. M. J. Am. Chem. Soc. 1952, 74, 4223.
17. Speziale, A. J.; Stephens, J. A.; Thompson, Q. E. J. Am. Chem. Soc. 1954, 76, 5011.
18. Matsushita, M.; Nagaoka, Y.; Hioki, H.; Fukuyama, Y.; Kodama, M. Chem. Lett. 1996, 1039.
19. Kodama, M.; Matsushita, M.; Terada, Y.; Takeuchi, A.; Yoshio, S.; Fukuyama, Y. Chem. Lett. 1997, 117.
20. Bradshaw, C. W.; Fu, H.; Shen, G.-J.; Wong, C.-H. J. Org. Chem. 1992, 57, 1526.
21. Meyers, A. I.; Berney, D. Org. Synth. 1990, 69, 55.