Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): Molecular dynamics simulations and kinetic studies of protein mutants

FEBS Letters

Volumn 581, Issue 16, 2007, Pages 2981-2987

  Floquet, Nicolas ^a   Mouilleron, Stéphane ^a   Daher, Rasha ^a   Maigret, Bernard ^b   Badet, Bernard ^a   Badet Denisot, Marie Ange ^a  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^b LORIA   (France)

Author keywords

Amidotransferases; Ammonia transfer; Glms; Molecular dynamics simulations; Site directed mutagenesis

Indexed keywords

ALANINE; AMMONIA; FRUCTOSE 6 PHOSPHATE; GLUTAMINE; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; MUTANT PROTEIN; PROTEIN; TRYPTOPHAN DERIVATIVE; VALINE;

ARTICLE; BACTERIUM; BINDING SITE; HYDROPHOBICITY; KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SIMULATION;

AMMONIA; BACTERIAL PROTEINS; BINDING SITES; BIOLOGICAL TRANSPORT; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GLUCOSAMINE; GLUCOSE-6-PHOSPHATE; GLUTAMINE; GLUTAMINE-FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; POINT MUTATION;

BACTERIA (MICROORGANISMS);

EID: 34250194661     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.05.068     Document Type: Article

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