Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: Evidence from the 1.8 Å crystal structure of the glutaminase domain of glucosamine 6- phosphate synthase

Structure

Volumn 4, Issue 7, 1996, Pages 801-810

  Isupov, Michail N ^a,b   Obmolova, Galya ^b   Butterworth, Susanna ^b   Badet Denisot, Marie Ange ^c   Badet, Bernard ^c   Polikarpov, Igor ^d   Littlechild, Jennifer A ^a   Teplyakov, Alexei ^b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c CNRS   (France)

^d LABORATÓRIO NACIONAL DE LUZ SÍNCROTRON   (Brazil)

Author keywords

catalytic mechanism; crystal structure; glucosamine 6 phosphate synthase; glutaminase domain; glutamine amidotransferase

Indexed keywords

EID: 0030586024     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(96)00087-1     Document Type: Article

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