Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 2: Structure-activity relationship studies on the benzopyran scaffold

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 13, 2007, Pages 3570-3574

  Richardson, Timothy I ^a   Norman, Bryan H ^a   Lugar, Charles W ^a   Jones, Scott A ^a   Wang, Yong ^a   Durbin, Jim D ^a   Krishnan, Venkatesh ^a   Dodge, Jeffrey A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Benzopyrans; ER selective ligands; Estrogen receptor

Indexed keywords

BENZOPYRAN DERIVATIVE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLOPENTANE DERIVATIVE; CYCLOPENTENE DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; SCAFFOLD PROTEIN;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SELECTIVITY; HUMAN; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

BENZOPYRANS; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; LIGANDS; MALE; MODELS, CHEMICAL; MODELS, MOLECULAR; SELECTIVE ESTROGEN RECEPTOR MODULATORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 34250182791     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.051     Document Type: Article

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