Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure

Circulation Research

Volumn 100, Issue 11, 2007, Pages 1643-1649

  Traverse, Jay H ^a,b   Chen, YingJie ^a   Hou, MingXiao ^a   Li, Yunfang ^a   Bache, Robert J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Coronary blood flow; Exercise; Heart failure; K+ATP channels; Myocardial oxygen consumption

Indexed keywords

8 PHENYLTHEOPHYLLINE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATASE (POTASSIUM); ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; EXERCISE; HEART MUSCLE OXYGEN CONSUMPTION; HEART VENTRICLE PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REST;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BLOOD FLOW VELOCITY; CARDIAC PACING, ARTIFICIAL; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; DOGS; EXERCISE TEST; EXERTION; GLYBURIDE; HEART; HEART FAILURE, CONGESTIVE; OXYGEN CONSUMPTION; PINACIDIL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RECEPTORS, PURINERGIC P1; REST; THEOPHYLLINE; VASODILATOR AGENTS;

EID: 34250178437     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.107.150219     Document Type: Article

References (36)

1. ATP channels in coronary vasodilation during exercise. Circulation. 1993;88:1245-1253.
2. Shryock JC, Belardinelli L. Adenosine and adenosine receptors in the cardiovascular system: biochemistry, physiology, and pharmacology. Am J Cardiol. 1997;79(12A):2-10.
3. Bardenheuer H, Schrader J. Supply-to-demand ratio for oxygen determines formation of adenosine by the heart. Am J Physiol. 1986;250:H173-H180.
4. Bache RJ, Dai XZ, Schwartz JS, Homans DC. Role of adenosine in coronary vasodilation during exercise. Circ Res. 1988;62:846-853.
5. Tune JD, Richmond KN, Gorman MW, Olsson RA, Feigl EO. Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise. Am J Physiol. 2000;278:H74-H84.
6. Yada T, Richmond KN, Van Bibber R, Kroll K, Feigl EO. Role of adenosine in local metabolic coronary vasodilation. Am J Physiol. 1999;276:H1425-H1433.
7. Traverse JH, Melchert P, Pierpont GL, Jones B, Crampton M, Bache RJ. Regulation of myocardial blood flow by oxygen consumption is maintained in the failing heart during exercise. Circ Res. 1999;84:401-408.
8. + channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure. Jpn Circ J. 2000;64:701-707.
9. Newman WH, Grossman SJ, Frankis MB, Webb JG. Increased myocardial adenosine release in heart failure. J Mol Cell Cardiol. 1984;16:577-580.
10. Funaya H, Kitakaze M, Node K, Minamino T, Komamura K, Hori M. Plasma adenosine levels increase in patients with chronic heart failure. Circulation. 1997;95:1363-1365.
11. Kitakaze M, Hori M, Morioka T, Minamino T, Takashima B, Okazaki Y, Node K, Konamura K, Iwakura K, Itoh T. α-Adrenoceptor activation increases ectosolic 5′-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C. Circulation. 1995;91:2226-2234.
12. Traverse JH, Chen Y, Crampton M, Voss S, Bache RJ. Increased extravascular forces limit endothelium-dependent and -independent coronary vasodilation in congestive heart failure. Cardiovasc Res. 2001;52:454-461.
13. Nichols CG, Lederer WJ. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am J Physiol. 1991;261:H1675- H1686.
14. ATP channels and adenosine in the control of coronary blood flow during exercise. J Appl Physiol. 2000;89:529-536.
15. ATP channel blockade. J Clin Invest. 1995;95:285-295.
16. Laxson DD, Homans DC, Bache RJ. Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. Am J Physiol. 1989;265:H1471-H1477.
17. Akatsuka Y, Egashira K, Katsuda Y, Narishige T, Ueno H, Shimokawa H. ATP-sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilation in the dog. Cardiovasc Res. 1994;28:906-911.
18. Hein TW, Kuo L. cAMP-independent dilation of coronary arterioles to adenosine. Role of nitric oxide, G proteins and KATP channels. Circ Res. 1999;85:634-642.
19. Silver PJ, Walus K, DiSalvo J. Adenosine mediated relaxation and activation of cyclic AMP-dependent protein kinase in coronary arterial smooth muscle. J Pharmacol Exp Ther. 1984;228:342.
20. Belloni FL, Hintze TH. Glibenclamide attenuates adenosine-induced bradycardia and coronary vasodilation. Am J Physiol. 1991;261:H720-H727.
21. + channel blocker, inhibits coronary autoregulation in anesthetized dogs. Circ Res. 1993;73:771-776.
22. Shen W, Asai K, Uechi M, Mathier MA, Shannon RP, Vatner SF, Ingwall JS. Progressive loss of myocardial ATP due to a loss of total purines during the development of heart failure in dogs. Circulation. 1999;100:2113-2118.
23. ATP channels to coronary vasomotor tone regulation is enhanced in exercising swine with a recent myocardial infarction. Am J Physiol. 2005;288:H1306-H1313.
24. Koumi S, Martin RL, Sato R. Alterations in ATP-sensitive potassium channel sensitivity to ATP in failing human hearts. Am J Physiol. 1997;272:H1656-H1665.
25. + current in human and rabbit ventricular myocytes. Circ Res. 1996;78:492-498.
26. 2Areceptor activation increases contractility in isolated perfused hearts. Am J Physiol. 2000;279:H1472-H1481.
27. Hein TW, Wang W, Zoghi B, Muthuchamy M, Kuo L. Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine. J Mol Cell Cardiol. 2001;33:271-282.
28. Varani K, Laghi-Pasini F, Cammuri A, Capecchi PL, Maccherini M, Diciolla F, Ceccatelli L, Lazzerini PE, Ulouglu C, Cattabeni F, Borea PA, Abbracchio MP. Changes of peripheral A2A adenosine receptors in chronic heart failure and cardiac transplantation. FASEB J. 2003;17:280-282.
29. Traverse JH, Chen Y, Hou M, Bache RJ. Inhibition of NO production increases myocardial blood flow and oxygen consumption in congestive heart failure. Am J Physiol. 2002;282:H2278-H2283.
30. Clementi E, Brown GC, Foxwell N, Moncada S. On the mechanism by which vascular endothelial cells regulate their oxygen consumption. Proc Natl Acad Sci U S A. 1999;96:1559-1562.
31. Li JM, Fenton RA, Cutler BS, Dobson JG. Adenosine enhances nitric oxide production by vascular endothelial cells. Am J Physiol. 1999;269:C519-C523.
32. 2A receptors mediate coronary microvascular dilation to adenosine: role of nitric oxide and ATP-sensitive potassium channels. J Pharm Exp Ther. 1999;291:655-664.
33. Smellie FW, Davis CW, Daly JW, Wells JN. Alkylxanthines: inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity. Life Sci. 1979;24:2475-2482.
34. Kelm M, Schafer S, Dahmann R, Doly B, Perings S, Decking UK, Schrader J, Strauer BE. Nitric oxide induced contractile dysfunction is related to a reduction in myocardial energy generation. Cardiovasc Res. 1997;36:185-194.
35. Sato N, Asai K, Okumura S, Takagi G, Shannon RP, Fujita-Yamaguchi Y, Ishikawa Y, Vatner SF, Vatner DE. Mechanisms of desensitization to a PDE inhibitor (milrinone) in conscious dogs with heart failure. Am J Physiol. 1999;276:H1699-1705.
36. Senzaki H, Smith CJ, Juang GJ, Isoda T, Mayer SP, Ohles A, Paolucci N, Tomaselli GF, Hare JM, Kass DA. Cardiac phosphodiesterase 5 (cGMP-specific) modulates β-adrenergic signaling in vivo and is down-regulated in heart failure. FASEB J. 2001;15:1718-1726.