Role of adenosine in local metabolic coronary vasodilation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 276, Issue 5 45-5, 1999, Pages

  Yada, Toyotaka ^a   Richmond, Keith Neu ^a   Van Bibber, Richard ^a   Kroll, Keith ^a   Feigl, Eric O ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

8 phenyltheophylline; Canine; Hyperemia

Indexed keywords

8 PHENYLTHEOPHYLLINE; ADENOSINE;

ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; DOG; HEART MUSCLE OXYGEN CONSUMPTION; HEART PACING; HEART RATE; HEART STIMULATION; LEFT CORONARY ARTERY; MALE; MATHEMATICAL MODEL; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0032989205     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.276.5.h1425     Document Type: Article

References (45)

1. Bache, R. J., X.-Z. Dai, J. S. Schwartz, and D. C. Homans. Role of adenosine in coronary vasodilation during exercise. Circ. Res. 62: 846-853, 1988.
2. Bassett, A. L., and F. F. Kao. Effects of paired stimulation on cardiac output in dogs at rest and during exercise. Am. J. Physiol. 216: 63-69, 1969.
3. Bassingthwaighte, J. B. Interstitial adenosine: the measurement, the interpretation. J. Mol. Cell. Cardiol. 24: 337-346, 1992.
4. Berne, R. M. Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am. J. Physiol. 204: 317-322, 1963.
5. Dole, W. P., N. Yamada, V. S. Bishop, and R. A. Olsson. Role of adenosine in coronary blood flow regulation after reductions in perfusion pressure. Circ. Res. 56: 517-524, 1985.
6. Duncker, D. J., R. Stubenitsky, and P. D. Verdouw. Autonomic control of vasomotion in the porcine coronary circulation during treadmill exercise: evidence for feed-forward β-adrenergic control. Circ. Res. 82: 1312-1322, 1998.
7. Feigl, E. O. Coronary physiology. Physiol. Rev. 63: 1-205, 1983.
8. Feldman, M. D., C. R. Ayers, M. R. Lehman, H. E. Taylor, V. L. Gordon, P. J. Sabia, D. Ras, T. C. Skalak, and J. Linden. Improved detection of ischemia-induced increases in coronary sinus adenosine in patients with coronary artery disease. Clin. Chem. 38: 256-262, 1992.
9. Gerlach, E., B. Deuticke, and R. H. Dreisbach. Der Nucleotid-Abbau im Herzmuskel bei Sauerstoffmangel und seine mögliche Bedeutung für die Coronardurchblutung. Naturwissenschaften 50: 228-229, 1963.
10. Gewirtz, H., P. Brown, and A. S. Most. Measurement of plasma adenosine concentration: methodological and physiological considerations. Proc. Soc. Exp. Biol. Med. 185: 93-100, 1987.
11. Gewirtz, H., R. A. Olsson, D. L. Brautigan, P. R. Brown, and A. S. Most. Adenosine's role in regulating basal coronary arteriolar tone. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H1030-H1036, 1986.
12. Gidday, J. M., H. E. Hill, R. Rubio, and R. M. Berne. Estimates of left ventricular interstitial fluid adenosine during catecholamine stimulation. Am. J. Physiol. 254 (Heart Circ. Physiol. 23): H207-H216, 1988.
13. 1-purinoceptor antagonist. Eur. J. Pharmacol. 75: 61-64, 1981.
14. Hanley, F., L. M. Messina, R. W. Baer, P. N. Uhlig, and J. I. E. Hoffman. Direct measurement of left ventricular interstitial adenosine. Am. J. Physiol. 245 (Heart Circ. Physiol. 14): H327-H335, 1983.
15. Hanley, F. L., M. T. Grattan, M. B. Stevens, and J. I. E. Hoffman. Role of adenosine in coronary autoregulation. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H558-H566, 1986.
16. Harter, H. L. Tables of range and studentized range. Ann. Math. Stat. 31: 1122-1147, 1960.
17. Herrmann, S. C., and E. O. Feigl. Adrenergic blockade blunts adenosine concentration and coronary vasodilation during hypoxia. Circ. Res. 70: 1203-1216, 1992.
18. Herrmann, S. C., and E. O. Feigl. Subtraction method for the high-performance liquid chromatographic measurement of plasma adenosine. J. Chromatogr. 574: 247-253, 1992.
19. 1-Adrenoceptor activity regulates release of adenosine from the ischemic myocardium in dogs. Circ. Res. 60: 631-639, 1987.
20. Klabunde, R. E., and D. G. Althouse. Adenosine metabolism in dog whole blood: effects of dipyridamole. Life Sci. 28: 2631-2641, 1981.
21. Koberstein, R. C., D. E. Pittman, and F. J. Klocke. Right atrial admixture in coronary venous blood. Am. J. Physiol. 216: 531-535, 1969.
22. Kroll, K., A. Deussen, and I. R. Sweet. Comprehensive model of transport and metabolism of adenosine and S-adenosylhomocysteine in the guinea pig heart. Circ. Res. 71: 590-604, 1992.
23. Kroll, K., and E. O. Feigl. Adenosine is unimportant in controlling coronary blood flow in unstressed dog hearts. Am. J. Physiol. 249 (Heart Circ. Physiol. 18): H1176-H1187, 1985.
24. Kroll, K., and G. V. Martin. Comparison of myocardial ATP, blood flow and cytosolic adenosine in demand ischemia and coronary occlusion. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H819-H828, 1995.
25. Kroll, K., and D. W. Stepp. Adenosine kinetics in the canine coronary circulation. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H1469-H1483, 1996.
26. Lammerant, J., and I. Becsei. Inhibition of pacing-induced coronary dilation by aminophylline. Cardiovasc. Res. 9: 532-537, 1975.
27. Maekawa, K., D. Saito, N. Obayashi, S. Uchida, and S. Haraoka. Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H166-H173, 1994.
28. Manfredi, J. P., and H. V. Sparks, Jr. Adenosine's role in coronary vasodilation induced by atrial pacing and norepinephrine. Am. J. Physiol. 243 (Heart Circ. Physiol. 12): H536-H545, 1982.
29. McKenzie, J. E., R. P. Steffen, and F. J. Haddy. Effect of theophylline on adenosine production in the canine myocardium. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H204-H210, 1987.
30. Miyashiro, J. K., and E. O. Feigl. Feedforward control of coronary blood flow via coronary β-receptor stimulation. Circ. Res. 73: 252-263, 1993.
31. Möser, G. H., J. Schrader, and A. Deussen. Turnover of adenosine in plasma of human and dog blood. Am. J. Physiol. 256 (Cell Physiol. 25): C799-C806, 1989.
32. Ontyd, J., and J. Schrader. Measurement of adenosine, inosine, and hypoxanthine in human plasma. J. Chromatogr. 307: 404-409, 1984.
33. Randall, J. R., and C. E. Jones. Adenosine antagonist aminophylline attenuates pacing-induced coronary functional hyperemia. Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H1-H7, 1985.
34. Ross, J., Jr., E. H. Sonnenblick, G. A. Kaiser, P. L. Frommer, and E. Braunwald. Electroaugmentation of ventricular performance and oxygen consumption by repetitive application of paired electrical stimuli. Circ. Res. 16: 332-342, 1965.
35. Rossen, J. D., H. Oskarsson, R. L. Minor, Jr., C. L. Talman, and M. D. Winniford. Effect of adenosine antagonism on metabolically mediated coronary vasodilation in humans. J. Am. Coll. Cardiol. 23: 1421-1426, 1994.
36. Saito, D., C. R. Steinhart, D. G. Nixon, and R. A. Olsson. Intracoronary adenosine deaminase reduces canine myocardial reactive hyperemia. Circ. Res. 49: 1262-1267, 1981.
37. Smellie, F. W., C. W. Davis, J. W. Daly, and J. N. Wells. Alkylxanthines: inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity. Life Sci. 24: 2475-2482, 1979.
38. Smith, F. D., L. G. D'Alecy, and E. O. Feigl. Cannula-tip coronary blood flow transducer for use in closed-chest animals. J. Appl. Physiol. 37: 592-595, 1974.
39. Stepp, D. W., R. Van Bibber, K. Kroll, and E. O. Feigl. Quantitative relation between interstitial adenosine concentra-tion and coronary blood flow. Circ. Res. 79: 601-610, 1996.
40. Tietjan, C. S., C. G. Tribble, J. M. Gidday, C. L. Phillips, L. Belardinelli, R. Rubio, and R. M. Berne. Interstitial adenosine in guinea pig hearts: an index obtained by epicardial disks. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1471-H1476, 1990.
41. Van Belle, H. Uptake and deamination of adenosine by blood. Species differences, effect of pH, ions, temperature and metabolic inhibitors. Biochim. Biophys. Acta 192: 124-132, 1969.
42. Van Bibber, R., D. W. Stepp, K. Kroll, and E. O. Feigl. The role of adenosine in norepinephrine-induced coronary vasodilation. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H557-H565, 1997.
43. Van Wylen, D. G. L., J. Willis, J. Sodhi, R. J. Weiss, R. D. Lasley, and R. M. Mentzer, Jr. Cardiac microdialysis to estimate interstitial adenosine and coronary blood flow. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1642-H1649, 1990.
44. Wangler, R. D., D. F. Dewitt, and H. V. Sparks, Jr. Effect of β-adrenergic blockade on nucleoside release from the hypoperfused isolated heart. Am. J. Physiol. 247 (Heart Circ. Physiol. 16): H330-H336, 1984.
45. Wangler, R. D., M. W. Gorman, C. Y. Wang, D. F. Dewitt, I. S. Chan, J. B. Bassingthwaighte, and H. V. Sparks. Transcapillary adenosine transport and interstitial adenosine concentration in guinea pig hearts. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H89-H106, 1989.