Iron (III) chelation and antioxidant properties of myo-inositol phosphorylated polymeric microspheres

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 4, 2007, Pages 597-601

  Iemma, Francesca ^a   Cirillo, Giuseppe ^a   Puoci, Francesco ^a   Trombino, Sonia ^a   Castiglione, Mariarosaria ^a   Picci, Nevio ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 O (4 VINYLBENZYL) MYO INOSITOL 1,3,5 ORTHOFORMATE; FERRIC ION; INOSITOL DERIVATIVE; UNCLASSIFIED DRUG; 4-O-(4-VINYLBENZYL)-MYO-INOSITOL 1,3,5-ORTHOFORMATE; ANTIOXIDANT; CHELATING AGENT; DRUG DERIVATIVE; ETHYLENE GLYCOL DIMETHACRYLATE; INOSITOL; IRON; METHACRYLIC ACID DERIVATIVE; MICROSPHERE; POLYMER;

ANIMAL CELL; ARTICLE; CHELATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; LIPID PEROXIDATION; MACROMOLECULE; NONHUMAN; PHOSPHORYLATION; POLYMERIZATION; RAT; ANIMAL; CELL MEMBRANE; CHEMISTRY; DRUG EFFECT; LIVER MICROSOME; METABOLISM; PRECIPITATION; SYNTHESIS;

ANIMALS; ANTIOXIDANTS; CELL MEMBRANE; CHELATING AGENTS; FERRIC COMPOUNDS; INOSITOL; IRON; LIPID PEROXIDATION; METHACRYLATES; MICROSOMES, LIVER; MICROSPHERES; PHOSPHORYLATION; POLYMERS; PRECIPITATION; RATS;

EID: 34250172404     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.4.0016     Document Type: Article

References (31)

1. Baudin, G., Glanzer, B. I., Swaminathan, K. S., Vasella, A. (1988) Synthesis of 1D- and 1L-myo-inositol 1,3,4,5-tetraphosphate. Helv. Chim. Acta 71: 1367-1378
2. Boots, A. W., Haenen, G. R., den Hartog, G. J., Bast, A. (2002) Oxidative damage shifts from lipid peroxidation to thiol arylation by catechol-containing antioxidants. Biochim. Biophys. Acta 1583: 279-284
3. Calo, L. A., Naso, A., Pagnin, E., Davis, P. A., Castoro, M., Corradin, R., Riegler, R., Cascone, C., Huber, W., Piccoli, A. (2004) Vitamin E-coated dialyzers reduce oxidative stress related proteins and markers in haemodialysis - a molecular biological approach. Clin. Nephrol. 62: 355-361
4. Carlson, G. P., Turner, M., Mantick, N. A. (2006) Effects of styrene and styrene oxide on glutathione-related antioxidant enzymes Toxicology 227: 211-226
5. Cooper, C. E., Vollaard, N. B. J., Choueiri, T., Wilson, M. T. (2002) Exercise, free radicals and oxidative stress. Biochem. Soc. Trans. 30: 280-285
6. Decreto Ministeriale (1986) Approvazione dei metodi ufficiali di analisi per i fertilizzanti. Gazz. Uff. Rep. Ital. 180: 158-160
7. Flores-Mosquera, M. F., Martin-Lomas, M., Chiara, J. L. (1998) Regiocontrolled acylation of myo-inositol orthoformate. Tetrahedron Lett. 39: 5085-5088
8. Graf, E., Eaton, J. W. (1990) Antioxidant functions of phytic acid. Free Radic. Biol. Med. 8: 61-69
9. Halliwell, B., Aeschbach, R., Lolinger, J., Aruoma, O. I. (1995) The characterization of antioxidants. Food Chem. Toxicol. 33: 601-617
10. Hawkins, P. T., Poyner, D. R., Jackson, T. R., Letcher, A. J., Lander, D. A., Irvine, R. F. (1993) Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate. Biochem. J. 294: 929-934
11. Iemma, F., Trombino, S., Puoci, F., Cirillo, G., Spizzirri, U. G., Muzzalupo, R., Picci, N. (2005) Synthesis and antioxidant efficiency of a new copolymer containing phosphorylated myo-inositol. Macromol. Biosci. 5: 1049-1056
12. Kitamura, Y., Nishikawa, A., Nakamura, H., Furukawa, F., Imazawa, T., Umemura, T., Uchida, K., Hirose, M. (2005) Effects of N-acetylcysteine, quercetin, and phytic acid on spontaneous hepatic and renal lesions in LEC rats. Toxicol. Pathol. 33: 584-592
13. Liu, Z. C., Hider, R. C. (2002) Design of iron chelators with therapeutic application. Coord. Chem. Rev. 232: 151-171
14. Minihane, A. M., Rimbach, G. (2002) Iron absorption and the iron binding and anti-oxidant properties of phytic acid. Int. J. Food Sci. Technol. 37: 741-748
15. Morais, I. P. A., Miro, M., Manera, M., Estela, J. M., Cerda, V., Souto, M. R. S., Rangel, A. O. S. S. (2004) Flow-through solid-phase based optical sensor for the multisyringe flow injection trace determination of orthophosphate in waters with chemiluminescence detection. Anal. Chim. Acta 506: 17-24
16. Munoz, A., Mas Torres, F., Estela, J. M., Cerda, V. (1997) Evaluation of spectrophotometric methods for determination of orthophosphates by sequential injection analysis. Anal. Chim. Acta 350: 21-29
17. Ohta, T., Nakano, T., Egashira, Y., Sanada, H. (1997) Antioxidant activity of ferulic acid β-glucuronide in the LDL oxidation system. Biosci. Biotechnol. Biochem. 61: 1942-1943
18. Phillippy, B. Q., Graf, E. (1997) Antioxidant functions of inositol 1,2,3-trisphosphate and inositol 1,2,3,6-tetrakisphosphate. Free Radic. Biol. Med. 22: 939-946
19. Pinchuk, I., Lichtenberg, D. (2002) The mechanism of action of anti-oxidants against lipoprotein peroxidation, evaluation based on kinetic experiments Prog. Lipid Res. 41: 279-314
20. Puoci, F., Iemma, F., Muzzalupo, R., Spizzirri, U. G., Trombino, S., Cassano, R., Picci, N., (2004) Spherical molecularly imprinted polymers (SMIPs) via a novel precipitation polymerization in the controlled delivery of sulfasalazine. Macromol. Biosci. 4: 22
21. Sala, M., Kolar, J., Strlic, M., Kocevar, M. (2006) Synthesis of myo-inositol 1,2,3-tris- and 1,2,3,5-tetrakis(dihydrogen phosphate)s as a tool for the inhibition of iron-gall-ink corrosion. Carbohydr. Res. 341: 897-902
22. Salo, S., Alanen, A., Leino, R., Bonderstam, S., Komu, M. (2002) The effect of haemosiderosis and blood transfusions on the T2 relaxation time and 1/T2 relaxation rate of liver tissue. Br. J. Radiol. 75: 24-27
23. Sanchez, J. M., Hidalgo, M., Salvado, V. (2001) Selective adsorption of gold (III) and palladium (II) on new phosphine sulphide-type chelating polymers bearing different spacer arms. Equilibrium and kinetic characterization. React. Funct. Polym. 46: 283-291
24. Sarmah, M. P., Shashidhar, M. S. (2003) Sulfonate protecting groups. Improved synthesis of scyllo-inositol and its orthoformate from myo-inositol. Carbohydr. Res. 338: 999-1001
25. Spiers, I. D., Barker, C. J., Chung, S. -K., Chang, Y. -T., Freeman, S., Gardiner, J. M., Hirst, P. H., Lambert, P. A., Michell, R. H., Poyner, D. R., Schwalbe, C. H., Smith, A. W., Solomons, K. R. H. (1996) Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (±)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates. Carbohydr. Res. 282: 81-99
26. Tatum, V. L., Changoit, C., Chow, C. K. (1990) Measurement of malondialdehyde by high performance liquid chromatography with fluorescence detection. Lipids 25: 226-229
27. Turi, J. L., Yang, F., Garrick, M. D., Piantadosi, C. A., Ghio, A. J. (2004) The iron cycle and oxidative stress in the lung. Free Radic. Biol. Med. 36: 850-857
28. Vacca, J. P., DeSolms, S., Huff, J. R., Billington, D. C., Bajer, R., Kulagowski, J. J., Mawer, I. M. (1989) The total synthesis of myo-inositol polyphosphates. Tetrahedron 45: 5679-5702
29. Wang, J. F., Cormack, P. A. G., Sherrington, D. C., Khoshdel, E. (2003) Monodisperse, molecularly imprinted polymer microspheres prepared by precipitation polymerization for affinity separation applications. Angew. Chem. Int. Ed. 42: 5336-5338
30. Ye, L., Mosbach, K. (2001) Molecularly imprinted microspheres as antibody binding mimics. React. Funct. Polym. 48: 149-157
31. Young, I. S., Woodside, J. V. (2001) Antioxidants in health and disease. J. Clin. Pathol. 53: 176-186