Antioxidant functions of inositol 1,2,3-trisphosphate and inositol 1,2,3,6-tetrakisphosphate

Free Radical Biology and Medicine

Volumn 22, Issue 6, 1997, Pages 939-946

  Phillippy, Brian Q ^a   Graf, Ernst ^b  

^a SOUTHERN REGIONAL RESEARCH CENTER   (United States)

^b Flavor Frontier   (United States)

Author keywords

Antioxidants; Free radicals; Inositol phosphates; Iron; Phosphatase; Phytase

Indexed keywords

FREE RADICAL; INOSITOL TETRAKISPHOSPHATE; INOSITOL TRISPHOSPHATE; IRON; PHOSPHATASE; PHYTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; ESCHERICHIA COLI; HYDROLYSIS; IRON CHELATION; KINETICS; NONHUMAN; OXIDATION; PEROXIDATION; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; ANTIOXIDANTS; ARACHIDONIC ACID; ASCORBIC ACID; ESCHERICHIA COLI; HYDROLYSIS; HYDROXYL RADICAL; INOSITOL PHOSPHATES; IRON; IRON CHELATING AGENTS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION;

ESCHERICHIA COLI;

EID: 0031050089     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00342-5     Document Type: Article

References (52)

1. Graf E., Eaton J. W. Suppression of colonic cancer by dietary phytic acid. Nutr. Cancer. 19:1993;11-19.
2. Shamsuddin A. M. Inositol phosphates have novel anticancer function. J. Nutr. 125:1995;725S-732S.
3. Graf E., Eaton J. W. Antioxidant functions of phytic acid. Free Radic. Biol. Med. 8:1990;61-69.
4. Hawkins P. T., Poyner D. R., Jackson T. R., Letcher A. J., Lander D. A., Irvine R. F. Inhibition of iron-catalyzed hydroxyl radical formation by inositol polyphosphates: A possible physiological function for myo-inositol hexakisphosphate. Biochem. J. 294:1993;929-934.
5. Cecconi O., Nelson R. M., Roberts W. G., Hanasaki K., Mannori G., Schultz C., Ulich T. R., Aruffo A., Bevilacqua M. P. Inositol polyanions. Noncarbohydrate inhibitors of L- and P-selectin that block inflammation. J. Biol. Chem. 269:1994;15060-15066.
6. Phillippy B. Q., Ullah A. H. J., Ehrlich K. C. Purification and some properties of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from immature soybean seeds. J. Biol. Chem. 269:1994;28393-28399.
7. Timerman A. P., Mayrleitner M. M., Lukas T. J., Chadwick C. C., Saito A., Watterson D. M., Schindler H., Fleischer S. Inositol polyphosphate receptor and clathrin assembly protein AP-2 are related proteins that form potassium-selective ion channels in planar lipid bilayers. Proc. Natl. Acad. Sci. USA. 89:1992;8976-8980.
8. Voglmaier S. M., Keen J. H., Murphy J.-E., Ferris C. D., Prestwich G. D., Snyder S. H., Theibert A. B. Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2. Biochim. Biophys. Res. Commun. 187:1992;158-163.
9. +-selective channels gated by, inositol polyphosphates. J. Biol. Chem. 269:1994;17826-17832.
10. Fukuda M., Aruga J., Niinobe M., Aimoto S., Mikoshiba K. Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II. J. Biol. Chem. 269:1994;29206-29211.
11. Llinas R., Sugimori M., Lang E. J., Morita M., Fukuda M., Niinobe M, Mikoshiba K. The inositol high-polyphosphate series blocks synaptic transmission by preventing vesicular fusion: A squid giant synapse study. Proc. Natl. Acad. Sci. USA. 91:1994;12990-12993.
12. Norris F. A., Ungewickell E., Majerus P. W. Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro. J. Biol. Chem. 270:1995;214-217.
13. Ye W., Ali N., Bembenek M. E., Shears S. B., Lafer E. M. Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3. J. Biol. Chem. 270:1995;1564-1568.
14. Graf E., Mahoney J. R., Bryant R. G., Eaton J. W. Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site. J. Biol. Chem. 259:1984;3620-3624.
15. Graf E., Empson K. L., Eaton J. W. Phytic acid. A natural antioxidant. J. Biol. Chem. 262:1987;11647-11650.
16. Spiers I. D., Freeman S., Poyner D. R., Schwalbe C. H. The first synthesis and iron binding studies of the natural product, myo-inositol 1,2,3-trisphosphate. Tetrahedron Lett. 36:1995;2125-2128.
17. Tomlinson R. V., Ballou C. E. Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase. Biochemistry. 1:1962;166-171.
18. Phillippy B. Q. Identification by two-dimensional NMR of inositol tris- and tetrakis (phosphates) formed from phytic acid by wheat phytase. J. Agric. Food Chem. 37:1989;1261-1265.
19. Hayakawa T., Suzuki K., Miura H., Ohno T., Igaue I. Myo-inositol polyphosphate intermediates in the dephosphorylation of phytic acid by acid phosphatase with phytase activity from rice bran. Agric. Biol. Chem. 54:1990;279-286.
20. Barrientos L., Scott J. J., Murthy P. P. N. Specificity of hydrolysis of phytic acid by alkaline phytase from lily pollen. Plant Physiol. 106:1994;1489-1495.
21. Barker C. J., French P. J., Moore A. J., Nilsson T., Berggren P.-O., Bunce C. M., Kirk C. J., Michell R. H. Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells. Biochem. J. 306:1995;557-564.
22. Phillippy B. Q., Bland J. M. Gradient ion chromatography of inositol phosphates. Anal. Biochem. 175:1988;162-166.
23. Heinonen J. K., Lahti R. J. A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase. Anal. Biochem. 113:1981;313-317.
24. Kakuda Y., Stanley D. W., van de Voort F. R. Determination of TBA number by high performance liquid chromatography. J. Am. Oil Chem. Soc. 58:1981;773-775.
25. 31P NMR, and Raman spectroscopic investigation. J. Am. Chem. Soc. 102:1980;3144-3148.
26. Minetti M., Forte T., Soriani M., Quaresima V., Menditto A., Ferrari M. Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. Biochem. J. 282:1992;459-465.
27. Greiner R., Konietzny U., Jany Kl.-D. Purification and characterization of two phytases from Escherichia coli. Arch. Biochem. Biophys. 303:1993;107-113.
28. Minotti G., Aust S. D. Redox cycling of iron and lipid peroxidation. Lipids. 27:1992;219-226.
29. Henderson B. R., Menotti E., Kuhn L. C. Iron regulatory proteins 1 and 2 bind distinct sets of RNA target sequences. J. Biol. Chem. 271:1996;4900-4908.
30. Balla G., Jacob H. S., Balla J., Rosenberg M., Nath K., Apple F., Eaton J. W., Vercellotti G. M. Ferritin: A cryoprotective antioxidant strategem of endothelium. J. Biol. Chem. 267:1992;18148-18153.
31. 2. Biochim. Biophys. Acta. 302:1973;316-328.
32. Van der Kaay J, Van Haastert P. J. M. Stereospecificity of inositol hexakisphosphate dephosphorylation by Paramecium phytase. Biochem. J. 312:1995;907-910.
33. Mandal N. C., Biswas B. B. Metabolism of inositol phosphates I. Phytase synthesis during germination in cotyledons of mung beans, Phaseolus aureus. Plant Physiol. 45:1970;4-7.
34. Bitar K., Reinhold J. G. Phytase and alkaline phosphatase activities in intestinal mucosae of rat, chicken, calf, and man. Biochim. Biophys. Acta. 268:1972;442-452.
35. Yang W.-J., Matsuda Y., Sano S., Masutani H., Nakagawa H. Purification and characterization of phytase from rat intestinal mucosa. Biochim. Biophys. Acta. 1075:1991;75-82.
36. Nogimori K., Hughes P. J., Glennon M. C., Hodgson M. E., Putney J. W. Jr, Shears S. B. Purification of an inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity from rat liver and the evaluation of its substrate specificity. J. Biol. Chem. 266:1991;16499-16506.
37. Powar V. K., Jagannathan V. Purification and properties of phytate-specific phosphatase from Bacillus subtilis. J. Bacteriol. 151:1982;1102-1108.
38. Ali N., Craxton A., Sumner M., Shears S. B. Effects of aluminum on the hepatic inositol polyphosphate phosphatase. Biochem. J. 305:1995;557-561.
39. McIntyre A., Gibson P. R., Young G. P. Butyrate production from dietary fiber and protection against large bowel cancer in a rat model. Gut. 34:1993;386-391.
40. 14C-phytate in rats: Effect of low and high dietary intakes. J. Nutr. 110:1980;1458-1472.
41. 3H]Phytic acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats. J. Nutr. 123:1993;713-720.
42. 3H]-Inositol hexaphosphate (phytic acid) is rapidly absorbed and metabolized by murine and human malignant cells in vitro. J. Nutr. 124:1994;861-868.
43. Sandberg A.-S., Andersson H. Effect of dietary phytase on the digestion of phytate in the stomach and small intestine of humans. J. Nutr. 118:1988;469-473.
44. Ames B. N., Gold L. S., Willett W. C. The causes and prevention of cancer. Proc. Natl. Acad. Sci. USA. 92:1995;5258-5265.
45. Floyd R. A. Direct demonstration that ferrous ion complexes of di- and triphosphate nucleotides catalyze hydroxyl free radical formation from hydrogen peroxide. Arch. Biochem. Biophys. 225:1983;263-270.
46. Phillippy B. Q., Johnston M. R., Tao S.-H., Fox M. R. S. Inositol phosphates in processed foods. J. Food Sci. 53:1988;496-499.
47. Kaufman H. W., Kleinberg I. Effect of pH on calcium binding by phytic acid and its inositol phosphoric acid derivatives and on the solubility of their calcium salts. Arch. Oral Biol. 16:1971;445-460.
48. Sandberg A.-S., Carlsson N.-G., Svanberg U. Effects of inositol tri-, tetra-, penta-, and hexaphosphates on in vitro estimation of iron availability. J. Food Sci. 54:1989;159-161 and 186.
49. Simpson C. J., Wise A. Binding of zinc and calcium to inositol phosphates (phytate) in vitro. Br. J. Nutr. 64:1990;225-232.
50. Tao S.-H., Fox M. R. S., Phillippy B. Q., Fry B. E. Jr, Johnson M. L., Johnston M. R. Effects of inositol phosphates on mineral utilization. Fed. Proc. 45:1986;819. abstr.
51. Lonnerdal B., Sandberg A.-S., Sandstrom B., Kunz C. Inhibitory effects of phytic acid and other inositol phosphates on zinc and calcium absorption in suckling rats. J. Nutr. 119:1989;211-214.
52. Lee B. J., Hendricks D. G. Phytic acid protective effect against beef round muscle lipid peroxidation. J. Food Sci. 60:1995;241-244.