Dimerization of cGMP-dependent Protein Kinase Iβ Is Mediated by an Extensive Amino-terminal Leucine Zipper Motif, and Dimerization Modulates Enzyme Function

Journal of Biological Chemistry

Volumn 278, Issue 50, 2003, Pages 50070-50079

  Richie Jannetta, Robyn ^a   Francis, Sharron H ^a   Corbin, Jackie D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; ENZYMES; MONOMERS; MUTAGENESIS;

MUTATIONS;

BIOCHEMISTRY;

ALANINE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; ISOLEUCINE; LEUCINE; LEUCINE ZIPPER PROTEIN; PROTEIN KINASE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; DIMERIZATION; ENZYME METABOLISM; ENZYME MODIFICATION; ENZYME SPECIFICITY; GENE DELETION; GENE DISRUPTION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; TANDEM REPEAT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CENTRIFUGATION, DENSITY GRADIENT; CHROMATOGRAPHY, GEL; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMANS; INSECTS; ISOLEUCINE; KINETICS; LEUCINE; LEUCINE ZIPPERS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

MAMMALIA;

EID: 0346118927     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306796200     Document Type: Article

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