Synthesis and antibacterial activity of new N-[2-(thiophen-3-yl)ethyl] piperazinyl quinolones

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 6, 2007, Pages 894-898

  Letafat, Bahram ^a   Emami, Saeed ^b   Mohammadhosseini, Negar ^c   Faramarzi, Mohammad Ali ^d   Samadi, Nasrin ^d   Shafiee, Abbas ^d   Foroumadi, Alireza ^d  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

^d Tehran University of Medical Science   (Iran)

Author keywords

Antibacterial activity; Oxime; Quinolone; Synthesis; Thiophene

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 (PHENYLMETHOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 HYDROXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 METHOXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 OXOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 (PHENYLMETHOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 (PHENYLMETHOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 HYDROXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 HYDROXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 METHOXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 METHOXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 OXOETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 (THIOPHEN 3 YL) 2 OXOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; CIPROFLOXACIN; NORFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; QUINOLONES; SPECTROPHOTOMETRY, INFRARED;

EID: 34250007601     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.894     Document Type: Article

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