Loop 1 structure of the leishmanial ICAM-L molecule is crucial for parasite binding and infection of host macrophages

International Journal for Parasitology

Volumn 37, Issue 8-9, 2007, Pages 1001-1011

  Chiang, Su Chi ^a   Chang, Cheng Chi ^a   Lin, Yi Chun ^a   Ng, Hang Pong ^a   Lee, Sho Tone ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

ICAM L; Leishmania; Leishmania infection; Loop structure; Macrophage binding

Indexed keywords

ANTISERUM; INTERCELLULAR ADHESION MOLECULE L; LYMPHOCYTE ANTIGEN; MERCAPTOETHANOL; UNCLASSIFIED DRUG;

ADHESION; FLAGELLATE; IMMUNE SYSTEM; INHIBITION; MAMMAL; PARASITE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL CYCLE PROGRESSION; CELL GROWTH; CONTROLLED STUDY; ENZYME IMMUNOASSAY; GENE DISRUPTION; HOST CELL; IMMUNOFLUORESCENCE TEST; INFECTION; LEISHMANIA; LEISHMANIASIS; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN STRUCTURE; RABBIT;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES; CELL CYCLE; CELL PROLIFERATION; LEISHMANIA; MACROPHAGES; MICE; PROTEIN BINDING; PROTEIN CONFORMATION; TIME FACTORS;

LEISHMANIA AMAZONENSIS; ORYCTOLAGUS CUNICULUS;

EID: 34250004374     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2007.01.005     Document Type: Article

References (31)

1. Alexander J., and Vickerman K. Fusion of host cells secondary lysosomes with the parasitophorous vacuoles of Leishmania mexicana infected macrophages. J. Protozool. 2 (1975) 502-508
2. Bray A.S. Leishmania mexicana mexicana: attachment and uptake of promastigotes to and by macrophages in vitro. J. Protozool. 30 (1983) 314-322
3. Brittingham A., Morrison C.J., Mcmaster W.R., McGire B.S., Chang K.P., and Mosser D.W. Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis. J. Immunol. 155 (1995) 3102-3111
4. Chang K.P., and Dwyer D.M. Multiplication of a human parasite (Leishmania donovani) in the phagolysosomes of hamster macrophages in vitro. Science 193 (1976) 678-680
5. Chang S.C., Kuzmenok O., Chiang S.C., and Lee S.T. An improved method for detection of Leishmania amostigotes by an antibody probe against the small subunit of Leishmanial ribonucleotide reductase. Parasitol. Res. 94 (2004) 243-245
6. Chiang S.C., Ali V., Huang A.L., Chu K.Y., and Lee S.T. Molecular, cellular and functional characterizations of a noval ICAM-like molecule of immunoglobulin superfamily from Leishmania mexicana amazonensis. Mol. Biochem. Parasitol. 112 (2001) 263-275
7. Chiang S.C., Chang S.C., and Lee S.T. ICAM-L gene is conserved only in Leishmania species in the family of kinetoplastida. Mol. Biochem. Parasitol. 124 (2002) 47-50
8. Da Silva R.P., Hall F.B., Joiner K.A., and Sacks D.L. CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages. J. Immunol. 143 (1989) 617-622
9. de Fougerolles A.R., Qin X., and Springer T.A. Characterization of the function of intercellular adhesive molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune response. J. Expt. Med. 179 (1994) 619-629
10. Dominguez M., and Torano A. Immune adherence-mediated opsonin-phagocytosis: the mechanism of Leishmania infection. J. Exp. Med. 189 (1999) 25-35
11. Fawcett J., Holness C.L., Needham L.A., Turley H., Gatter K.C., Mason D.Y., and Simmons D.L. Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature 36 (1992) 481-484
12. Handman E., and Goding J.W. The Leishmania receptor for macrophage is a lipid-containing glycoconjugate. EMBO J. 4 (1985) 329-336
13. Holness C.L., Bates P.A., Littler A.J., Buckley C.D., McDowal A., Bossy D., Hogg N., and Simmon D.L. Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function associated antigen I. J. Biol. Chem. 270 (1995) 877-884
14. Joshi P.B., Kelly B.L., Kamhawi S., Sacks D.L., and McMaster W.R. Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor. Mol. Biochem. Parasitol. 120 (2002) 33-40
15. Kelleher M., Bacic A., and Handman E. Identification of a macrophage-binding determinant on lipophosphoglycan from Leishmania major promastigotes. Proc. Natl. Acad. Sci. USA 89 (1992) 6-10
16. Kuzmenok O.I., Chiang S.C., Lin Y.C., and Lee S.T. Retardation of cell cycle progression of macrophages from G1 to S phase by ICAM-L from Leishmania. Int. J. Parasitol. 35 (2005) 1547-1555
17. Lee S.T., Tarn C., and Chang K.P. Characterization of the switch of kinetoplast DNA minicircle dominance during development and reversion of drug resistance in Leishmania. Mol. Biochem. Parasitol. 58 (1993) 187-203
18. 2 protein in hydroxyurea-resistant Leishmania mexicana amazonensis. Mol. Biochem. Parasitol. 102 (1999) 263-271
19. Mendez S., Nell M., and Alunda J.M. Leishmania infantum: Infection of macrophages in vitro with promastigotes. Int. J. Parasitol. 26 (1996) 619-622
20. Mosser D.M., and Edelson P.J. The third component of complement (C3) is responsible for the intracellular survival of Leishmania major. Nature 327 (1987) 329-331
21. Mosser D.M., and Handman E. Treatment of murine macrophages with interferon-gamma inhibits their ability to bind leishmanial promastigotes. J. Leukol. Biol. 52 (1992) 369-376
22. Mosser D.M., Vlassara H., Edelson P.J., and Cerami A. Leishmania promastigotes are recognized by the macrophage receptor for advanced glycosylation endproducts. J. Exp. Med. 165 (1987) 140-144
23. Mosser D.M., Springer T.A., and Diamond M.S. Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18). J. Cell Biol. 116 (1992) 511-520
24. Pearson R.D., Romito R., Symes P.H., and Harcus J.L. Interaction of Leishmania donovani promastigotes with human monocyte-derived macrophages: parasite entry, intracellular survival and multiplication. Infect. Immun. 32 (1981) 1249-1253
25. Rizvi F.S., Quaissi M.A., Marty B., Santoro F., and Capron A. The major surface protein of Leishmania promastigotes is a fibronectin-like molecule. Eur. J. Immunol. 18 (1988) 473-476
26. Rouslahti E. RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12 (1996) 297-715
27. Soteriadou K.P., Remoundos M.S., Katsikas M.C., Tzinia A.K., Tsikaris V., Sakarellos C., and Tzartos S.J. The Ser-Arg-Tyr-Asp region of the major surface glycoprotein of Leishmania mimics the Arg-Gly-Asp-Ser cell attachment region of fibronectin. J. Biol. Chem. 267 (1992) 13980-13985
28. Späth G.F., Epstein L., Leader B., Singer S.M., Adila H.A., Turco S.J., and Beverley S.M. Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major. Proc. Natl. Acad. Sci. USA 97 (2000) 9258-9263
29. Talamas-Rohana P., Wright S.D., Lennartz M.R., and Russell D.G. Lipophosphoglycan from Leishmania mexicana promastigotes binds of members of the CR3, P150,95 and LFA-1 family of integrins. J. Immunol. 144 (1990) 4817-4824
30. Wilson M.E., and Pearson R.D. Evidence that Leishmania donovana ultilizes a manose receptor on human mononuclear phagocytes to establish intracellular parasitism. J. Immunol. 136 (1986) 4681-4688
31. Wyler D.J., Sypek J.P., and McDonald J.A. In vitro parasite monocyte interactions in human Leishmaniasis: possible role of fibronectin in parasite attachment. Immunology 49 (1985) 305-311