Unexpected effect of a Bacteroides conjugative transposon, CTnDOT, on chromosomal gene expression in its bacterial host

Molecular Microbiology

Volumn 64, Issue 6, 2007, Pages 1562-1571

  Moon, Kyung ^a   Sonnenburg, Justin ^b   Salyers, Abigail A ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTEROIDES THETAIOTAOMICRON; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; HOMOLOGOUS RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; TRANSPOSON; UPREGULATION;

BACTERIAL PROTEINS; BACTEROIDES; CHROMOSOMES, BACTERIAL; CONJUGATION, GENETIC; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); BACTEROIDES; BACTEROIDES THETAIOTAOMICRON;

EID: 34249996213     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2007.05756.x     Document Type: Article

References (39)

1. Bartlett, J.G. (1983) Recent developments in the management of anaerobic infections. Rev Infect Dis 5 : 235 245.
2. Cerdeno-Tarraga, A.M., Patrick, S., Crossman, L.C., Blakely, G., Abratt, V., Lennard, N., et al. (2005) Extensive DNA inversions in the B. fragilis genome control variable gene expression. Science 307 : 1463 1465.
3. Cheng, Q., Paszkiet, B.J., Shoemaker, N.B., Gardner, J.F. Salyers, A.A. (2000) Integration and excision of a Bacteroides conjugative transposon, CTnDOT. J Bacteriol 182 : 4035 4043.
4. Cheng, Q., Sutanto, Y., Shoemaker, N.B., Gardner, J.F. Salyers, A.A. (2001) Identification of genes required for the excision of CTnDOT, a Bacteroides conjugative transposon. Mol Microbiol 41 : 625 632.
5. Cooper, A.J., Kalinowski, A.P., Shoemaker, N.B. Salyers, A.A. (1997) Construction and characterization of a Bacteroides thetaiotaomicron recA mutant: transfer of Bacteroides integrated conjugative elements is RecA independent. J Bacteriol 179 : 6221 6227.
6. Gorbach, S.L. Bartlett, J.G. (1974a) Anaerobic infections. 1. N Engl J Med 290 : 1177 1184.
7. Gorbach, S.L. Bartlett, J.G. (1974b) Anaerobic infections (second of three parts). N Engl J Med 290 : 1237 1245.
8. Gorbach, S.L. Bartlett, J.G. (1974c) Anaerobic infections (third of three parts). N Engl J Med 290 : 1289 1294.
9. Hamscher, G., Sczesny, S., Hoper, H. Nau, H. (2002) Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Anal Chem 74 : 1509 1518.
10. Jones, B.M., Geary, I., Lee, M.E. Duerden, B.I. (1989) Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections. Antimicrob Agents Chemother 33 : 970 972.
11. Kummerer, K. (2004) Resistance in the environment. J Antimicrob Chemother 54 : 311 320.
12. Kuwahara, T., Yamashita, A., Hirakawa, H., Nakayama, H., Toh, H., Okada, N., et al. (2004) Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation. Proc Natl Acad Sci USA 101 : 14919 14924.
13. Lai, E.M., Shih, H.W., Wen, S.R., Cheng, M.W., Hwang, H.H. Chiu, S.H. (2006) Proteomic analysis of Agrobacterium tumefaciens response to the Vir gene inducer acetosyringone. Proteomics 6 : 4130 4136.
14. Li, L.Y., Shoemaker, N.B. Salyers, A.A. (1993) Characterization of the mobilization region of a Bacteroides insertion element (NBU1) that is excised and transferred by Bacteroides conjugative transposons. J Bacteriol 175 : 6588 6598.
15. Li, L.Y., Shoemaker, N.B. Salyers, A.A. (1995) Location and characteristics of the transfer region of a Bacteroides conjugative transposon and regulation of transfer genes. J Bacteriol 177 : 4992 4999.
16. Loesche, W.J. (1999) The antimicrobial treatment of periodontal disease: changing the treatment paradigm. Crit Rev Oral Biol Med 10 : 245 275.
17. Moon, K., Shoemaker, N.B., Gardner, J.F. Salyers, A.A. (2005) Regulation of excision genes of the Bacteroides conjugative transposon CTnDOT. J Bacteriol 187 : 5732 5741.
18. Moore, W.E., Cato, E.P. Holdeman, L.V. (1978) Some current concepts in intestinal bacteriology. Am J Clin Nutr 31 : S33 S42.
19. Nikolich, M.P., Hong, G., Shoemaker, N.B. Salyers, A.A. (1994) Evidence for natural horizontal transfer of tetQ between bacteria that normally colonize humans and bacteria that normally colonize livestock. Appl Environ Microbiol 60 : 3255 3260.
20. Radvar, M., Pourtaghi, N. Kinane, D.F. (1996) Comparison of 3 periodontal local antibiotic therapies in persistent periodontal pockets. J Periodontol 67 : 860 865.
21. Salyers, A.A. (1993) Gene transfer in the mammalian intestinal tract. Curr Opin Biotechnol 4 : 294 298.
22. Salyers, A.A., Whittle, G. Shoemaker, N.B. (2004) Conjugative and mobilizable transposons. In Microbial Evolution: Gene Establishment, Survival, and Exchange. Miller, R.V. Day, M.J. (eds). Washington, DC : American Society for Microbiology Press, pp. 125 143.
23. Sapadin, A.N. Fleischmajer, R. (2006) Tetracyclines: nonantibiotic properties and their clinical implications. J Am Acad Dermatol 54 : 258 265.
24. Shoemaker, N.B. Salyers, A.A. (1987) Facilitated transfer of IncP beta R751 derivatives from the chromosome of Bacteroides uniformis to Escherichia coli recipients by a conjugative Bacteroides tetracycline resistance element. J Bacteriol 169 : 3160 3167.
25. Shoemaker, N.B., Getty, C., Guthrie, E.P. Salyers, A.A. (1986) Regions in Bacteroides plasmids pBFTM10 and pB8-51 that allow Escherichia coli-Bacteroides shuttle vectors to be mobilized by IncP plasmids and by a conjugative Bacteroides tetracycline resistance element. J Bacteriol 166 : 959 965.
26. Shoemaker, N.B., Barber, R.D. Salyers, A.A. (1989) Cloning and characterization of a Bacteroides conjugal tetracycline-erythromycin resistance element by using a shuttle cosmid vector. J Bacteriol 171 : 1294 1302.
27. Shoemaker, N.B., Wang, G.R., Stevens, A.M. Salyers, A.A. (1993) Excision, transfer, and integration of NBU1, a mobilizable site-selective insertion element. J Bacteriol 175 : 6578 6587.
28. Shoemaker, N.B., Vlamakis, H., Hayes, K. Salyers, A.A. (2001) Evidence for extensive resistance gene transfer among Bacteroides spp and between Bacteroides and other genera in the human colon. Appl Environ Microbiol 67 : 561 568.
29. Smith, C.J. Parker, A.C. (1993) Identification of a circular intermediate in the transfer and transposition of Tn4555, a mobilizable transposon from Bacteroides spp. J Bacteriol 175 : 2682 2691.
30. Sonnenburg, J.L., Xu, J., Leip, D.D., Chen, C.H., Westover, B.P., Weatherford, J., et al. (2005) Glycan foraging in vivo by an intestine-adapted bacterial symbiont. Science 307 : 1955 1959.
31. Stevens, A.M., Shoemaker, N.B. Salyers, A.A. (1990) The region of a Bacteroides conjugal chromosomal tetracycline resistance element which is responsible for production of plasmid-like forms from unlinked chromosomal DNA might also be involved in transfer of the element. J Bacteriol 172 : 4271 4279.
32. Stevens, A.M., Shoemaker, N.B., Li, L.Y. Salyers, A.A. (1993) Tetracycline regulation of genes on Bacteroides conjugative transposons. J Bacteriol 175 : 6134 6141.
33. Wade, W.G., Moran, J., Morgan, J.R., Newcombe, R. Addy, M. (1992) The effects of antimicrobial acrylic strips on the subgingival microflora in chronic periodontitis. J Clin Periodontol 19 : 127 134.
34. Wei, Y. Bechhofer, D.H. (2002) Tetracycline induces stabilization of mRNA in Bacillus subtilis. J Bacteriol 184 : 889 894.
35. Whittle, G., Hund, B.D., Shoemaker, N.B. Salyers, A.A. (2001) Characterization of the 13 kb ermF region of Bacteroides conjugative transposon, CTnDOT. Appl Environ Microbiol 67 : 3488 3495.
36. Whittle, G., Shoemaker, N.B. Salyers, A.A. (2002a) The role of Bacteroides conjugative transposons in the dissemination of antibiotic resistance genes. Cell Mol Life Sci 59 : 2044 2054.
37. Whittle, G., Shoemaker, N.B. Salyers, A.A. (2002b) Characterization of genes involved in modulation of conjugal transfer of the Bacteroides conjugative transposon CTnDOT. J Bacteriol 184 : 3839 3847.
38. Whittle, G., Hamburger, N., Shoemaker, N.B. Salyers, A.A. (2006) A bacteroides conjugative transposon, CTnERL, can transfer a portion of itself by conjugation without excising from the chromosome. J Bacteriol 188 : 1169 1174.
39. Xu, J., Bjursell, M.K., Himrod, J., Deng, S., Carmichael, L.K., Chiang, H.C., et al. (2003) A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science 299 : 2074 2076.