The application of eye-tracking technology in the study of autism

Journal of Physiology

Volumn 581, Issue 3, 2007, Pages 893-898

  Boraston, Zillah ^a   Blakemore, Sarah Jayne ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; COMMUNICATION DISORDER; CONCEPT FORMATION; DIAGNOSTIC IMAGING; ELECTROENCEPHALOGRAM; EMOTION; EYE FIXATION; EYE MOVEMENT; EYE TRACKING; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GAZE; HUMAN; IMAGE ANALYSIS; INFRARED RADIATION; LANGUAGE DISABILITY; NEUROIMAGING; PATTERN RECOGNITION; PRIORITY JOURNAL; REVIEW; SOCIAL BEHAVIOR; SOCIAL INTERACTION; BEHAVIORAL SCIENCE; MEDICAL RESEARCH; PHENOTYPE; SOCIAL ISOLATION; TASK PERFORMANCE;

AUTISTIC DISORDER; EYE MOVEMENTS; FIXATION, OCULAR; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTERPERSONAL RELATIONS; MAGNETIC RESONANCE IMAGING; NONVERBAL COMMUNICATION; PATTERN RECOGNITION, VISUAL; PHENOTYPE; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; SOCIAL BEHAVIOR; VISUAL PERCEPTION;

EID: 34249995411     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.133587     Document Type: Review

References (42)

1. Abell F, Happe F & Frith U (2000). Do triangles play tricks?Attribution of mental states to animated shapes in normal and abnormal development. Cognitive Dev 15, 1-16.
2. Adolphs R, Gosselin F, Buchanan TW, Tranel D, Schyns P & Damasio AR (2005). A mechanism for impaired fear recognition after amygdala damage. Nature 433, 68-72.
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR Fourth Edition. American Psychiatric Publishing (2000).
4. Baird G, Simonoff E, Pickles A, Chandler S, Loucas T, Meldrum D & Charman T (2006). Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: The Special Needs and Autism Project (SNAP). Lancet 368, 210-215.
5. Baron-Cohen S, Leslie AM & Frith U (1985). Does the autistic child have a 'theory of mind'? Cognition 21, 37-46.
6. Boraston Z, Blakemore SJ, Chilvers R & Skuse D (2007). Impaired sadness recognition is linked to social interaction deficit in autism. Neuropsychologia 45, 1501-1510.
7. Castelli F, Frith C, Happe F & Frith U (2002). Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain 125, 1839-1849.
8. Clarke AH, Ditterich J, Druen K, Schonfeld U & Steineke C (2002). Using high frame rate CMOS sensors for three-dimensional eye tracking. Behav Res Methods Instrum Comput 34, 549-560.
9. Corden B, Chilvers R & Skuse D (2007). Avoidance of emotionally arousing stimuli predicts social-perceptual impairment in Aspergers syndrome. Neuropsychologia (in press).
10. Dalton KM, Nacewicz BM, Alexander AL & Davidson RJ (2006). Gaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism. Biol Psychiatry 61, 512-520.
11. Dalton KM, Nacewicz BM, Johnstone T, Schaefer HS, Gernsbacher MA, Goldsmith HH, Alexander AL & Davidson RJ (2005). Gaze fixation and the neural circuitry of face processing in autism. Nature Neurosci 8, 519-526.
12. Fombonne E (1999). The epidemiology of autism: A review. Psychol Med 29, 769-786.
13. Gosselin F & Schyns PG (2001). Bubbles: A technique to reveal the use of information in recognition tasks. Vision Res 41, 2261-2271.
14. Gramatikov BI, Zalloutm OH, Wu YK, Hunter DG & Guyton DL (2007). Directional eye fixation sensor using birefringence-based foveal detection. Appl Optics 46, 1809-1818.
15. Grossman JB, Klin A, Carter AS & Volkmar FR (2000). Verbal bias in recognition of facial emotions in children with Asperger syndrome. J Child Psychol Psychiatry 41, 369-379.
16. Jemel B, Mottron L & Dawson M (2006). Impaired face processing in autism: Fact or artefact?J Autism Dev Disord 36, 91-106.
17. Joseph RM & Tager-Flusberg H (2004). The relationship of theory of mind and executive functions to symptom type and severity in children with autism. Dev Psychopathol 16, 137-155.
18. Kanner L (1943). Autistic disturbances of affective contact. Nervous Child 2, 217-250. 1943
19. Kemner C & van Engeland H (2003). Autism and visual fixation. Am J Psychiatry 160, 1358-1359.
20. Klin A, Jones W, Schultz R & Volkmar F (2003). The enactive mind, or from actions to cognition: Lessons from autism. Philos Trans R Soc Lond B Biol Sci 358, 345-360.
21. Klin A, Jones W, Schultz R, Volkmar F & Cohen D (2002a). Defining and quantifying the social phenotype in autism. Am J Psychiatry 159, 895-908.
22. Klin A, Jones W, Schultz R, Volkmar F & Cohen D (2002b). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Arch Gen Psychiatry 59, 809-816.
23. Klin A, Schultz R & Cohen D (2000). Theory of mind in action: developmental perspectives on social neuroscience. In Understanding Other Minds: Perspectives from Developmental Neuroscience, ed. Baron-Cohen S, Tager-Flusberg H & Cohen D, 2nd edn, pp. 357-388. Oxford University Press, Oxford.
24. Langdell T (1978). Recognition of faces: An approach to the study of autism. J Child Psychol Psychiatry 19, 255-268.
25. Luria SM & Strauss MS (1978). Comparison of eye movements over faces in photographic positives and negatives. Perception 7, 349-358.
26. Merin N, Young GS, Ozonoff S & Rogers SJ (2006). Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at risk for autism from comparison infants. J Autism Dev Disord 37, 108-121.
27. Norton D & Stark L (1971). Eye movements and visual perception. Sci Am 224, 35-43.
28. Pelphrey KA, Sasson NJ, Reznick JS, Paul G, Goldman BD & Piven J (2002). Visual scanning of faces in autism. J Autism Dev Disord 32, 249-261.
29. Pickles A, Bolton P, Macdonald H, Bailey A, Le Couteur A, Sim CH & Rutter M (1995). Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: A twin and family history study of autism. Am J Human Genet 57, 717-726.
30. Piven J (2001). The broad autism phenotype: A complementary strategy for molecular genetic studies of autism. Am J Med Genet 105, 34-35.
31. Ponnet KS, Roeyers H, Buysse A, De Clercq A & Van der Heyden E (2004). Advanced mind-reading in adults with Asperger syndrome. Autism 8, 249-266.
32. Schultz RT (2005). Developmental deficits in social perception in autism: The role of the amygdala and fusiform face area. Int J Dev Neurosci 23, 125-141.
33. Schultz RT, Gauthier I, Klin A, Fulbright RK, Anderson AW, Volkmar F, Skudlarski P, Lacadie C, Cohen DJ & Gore JC (2000). Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome. Arch Gen Psychiatry 57, 331-340.
34. Schultz RT, Grelotti DJ, Klin A, Kleinman J, Van der Gaag C, Marois R & Skudlarski P (2003). The role of the fusiform face area in social cognition: Implications for the pathobiology of autism. Philos Trans R Soc Lond B Biol Sci 358, 415-427.
35. Spezio ML, Adolphs R, Hurley RS & Piven J (2007). Abnormal use of facial information in high-functioning autism. J Autism Dev Disord (in press).
36. Sumi S, Taniai H, Miyachi T & Tanemura M (2006). Sibling risk of pervasive developmental disorder estimated by means of an epidemiologic survey in Nagoya, Japan. J Human Genet 51, 518-522.
37. van der Geest JN, Kemner C, Camfferman G, Verbaten MN & van Engeland H (2002a). Looking at images with human figures: Comparison between autistic and normal children. J Autism Dev Disord 32, 69-75.
38. van der Geest JN, Kemner C, Verbaten MN & van Engeland H (2002b). Gaze behavior of children with pervasive developmental disorder toward human faces: A fixation time study. J Child Psychol Psychiatry 43, 669-678.
39. Volkmar FR, Lord C, Bailey A, Schultz RT & Klin A (2004). Autism and pervasive developmental disorders. J Child Psychol Psychiatry 45, 135-170.
40. Walker-Smith GJ, Gale AG & Findlay JM (1977). Eye movement strategies involved in face perception. Perception 6, 313-326.
41. Wing L & Gould J (1979). Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. J Autism Dev Disord 9, 11-29.
42. Yin RK (1969). Looking at upside-down faces. J Exp Psychol 81, 141-145.