GABAergic mechanisms in absence epilepsy: A computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats

European Journal of Neuroscience

Volumn 25, Issue 9, 2007, Pages 2783-2790

  Bouwman, Brigitte M ^a   Suffczynski, Piotr ^b,c   Lopes Da Silva, Fernando H ^d   Maris, Eric ^a,e   Van Rijn, Clementina M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b Dutch Epilepsy Clinics Foundation   (Netherlands)

^c UNIVERSITY OF WARSAW   (Poland)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Cortex; Hazard rate; SWD properties; Thalamus

Indexed keywords

4 AMINOBUTYRIC ACID; VIGABATRIN;

ABSENCE; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SIMULATION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; EPILEPTIC DISCHARGE; GABAERGIC SYSTEM; HAZARD; IN VIVO STUDY; MALE; MATHEMATICAL MODEL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE; THALAMUS NUCLEUS; WISTAR ALBINO GLAXO RAT;

ACTION POTENTIALS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTICONVULSANTS; BRAIN; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; EPILEPSY, ABSENCE; GAMMA-AMINOBUTYRIC ACID; MALE; NEURAL INHIBITION; NEURAL PATHWAYS; NEURONS; RATS; SYNAPTIC TRANSMISSION; THALAMUS; VIGABATRIN;

EID: 34249989696     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05533.x     Document Type: Article

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